Projects funded by the NCN

Pessimism as cognitive biomarker of depression in animal model

Call: OPUS 7 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Molecular markers of stress resilience in animal model of depression

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii PAN

The molecular basis of stress-induced anxiety and affective disorders

Call: OPUS 2 , Panel: NZ2

Principal investigator: dr Michał Korostyński

Instytut Farmakologii PAN

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

Call: OPUS 25 , Panel: NZ4

Principal investigator: prof. Krzysztof Tokarski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

Call: OPUS 22 , Panel: HS6

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of the immune checkpoints in the pathomechanism of depressive disorders.

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Marta Kubera

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Katarzyna Głombik

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

Call: OPUS 19 , Panel: NZ5

Principal investigator: dr hab. Bernadeta Szewczyk

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Targeting senescent brain cells to improve cognitive function in animal models of ageing and depression

Call: OPUS 18 , Panel: NZ4

Principal investigator: prof. Ewa Sikora

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Small Changes - Huge Impact: The role of S-palmitoylation and S-nitrosylation interplay in the mice model of depression

Call: SONATA BIS 7 , Panel: NZ4

Principal investigator: dr hab. Jakub Włodarczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

Call: PRELUDIUM 13 , Panel: NZ5

Principal investigator: dr Anna Rafało-Ulińska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The effects of thyroid hormones in the brain in an animal model of depression

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Justyna Brodowicz

Instytut Farmakologii Polskiej Akademii Nauk

Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Molecular characteristics of stress-resilient phenotype using mice models.

Call: OPUS 12 , Panel: NZ4

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like beha...

Call: PRELUDIUM 12 , Panel: NZ4

Principal investigator: dr Patrycja Pańczyszyn-Trzewik

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

Effect of co-treatment with fluoxetine and zinc in a chronic restraint stress (CRS) animal model of depression

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Paulina Misztak

Uniwersytet Jagielloński - Collegium Medicum

Synthesis and pharmacological characterization of structurally diverse chemical analogues of compound PO-10 as multiple ...

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Zagórska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Molecular mechanisms of lithium action in depression and mania: animal model and clinical study in bipolar disorder

Call: OPUS 11 , Panel: NZ5

Principal investigator: prof. Joanna Twarowska-Hauser

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Dariusz Żurawek

Instytut Farmakologii PAN

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Trojan

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk