Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the brain metabolism in the context of therapy

2020/39/D/NZ7/01610

Keywords:

brain depression an animal model of depression epigenetic changes metabolism neuroendocrinology physical exercises leki przeciwdepresyjne

Descriptors:

  • NZ4_11: Metabolism
  • NZ7_3: Physical culture and health promotion
  • NZ4_8: Neuroendocrinology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Elżbieta Głombik 

Number of co-investigators in the project: 4

Call: SONATA 16 - announced on 2020-09-15

Amount awarded: 1 440 820 PLN

Project start date (Y-m-d): 2021-08-05

Project end date (Y-m-d): 2024-08-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Contribution of changes in the orexin system and energy sensors in the brain in depressive disorder - a study in an animal model.
    Authors:
    Katarzyna Głombik , Magdalena Kukla-Bartoszek, Katarzyna Curzytek , Agnieszka Basta-Kaim , Bogusława Budziszewska
    Academic press:
    Pharmacological Reports (rok: 2024, tom: 76, strony: 51-71), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s43440-023-00559-0 - link to the publication
  2. The Effects of Prenatal Dexamethasone Exposure on Brain Metabolic Homeostasis in Adulthood: Implications for Depression
    Authors:
    Katarzyna Głombik , Magdalena Kukla-Bartoszek , Katarzyna Curzytek , Jan Detka , Agnieszka Basta-Kaim , Bogusława Budziszewska
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: -, strony: -), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24021156 - link to the publication
  3. Hormonal Regulation of Oxidative Phosphorylation in the Brain in Health and Disease
    Authors:
    Katarzyna Głombik, Jan Detka, Bogusława Budziszewska
    Academic press:
    Cells (rok: 2021, tom: -, strony: -), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10112937 - link to the publication
  4. Hormonal Regulation of Oxidative Phosphorylation in the Brain in Health and Disease
    Authors:
    Katarzyna Głombik, Jan Detka, Bogusława Budziszewska
    Academic press:
    Cells (rok: 2021, tom: -, strony: -), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10112937 - link to the publication
  5. The Effects of Prenatal Dexamethasone Exposure on Brain Metabolic Homeostasis in Adulthood: Implications for Depression
    Authors:
    Katarzyna Głombik , Magdalena Kukla-Bartoszek , Katarzyna Curzytek , Jan Detka , Agnieszka Basta-Kaim , Bogusława Budziszewska
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: -, strony: -), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24021156 - link to the publication

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