Projects funded by the NCN

Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

Call: OPUS 25 , Panel: NZ4

Principal investigator: prof. Krzysztof Tokarski

Instytut Farmakologii PAN

Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

Call: OPUS 22 , Panel: HS6

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

The role of the immune checkpoints in the pathomechanism of depressive disorders.

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii PAN

Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Targeting senescent brain cells to improve cognitive function in animal models of ageing and depression

Call: OPUS 18 , Panel: NZ4

Principal investigator: prof. Ewa Zofia Sikora

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Small Changes - Huge Impact: The role of S-palmitoylation and S-nitrosylation interplay in the mice model of depression

Call: SONATA BIS 7 , Panel: NZ4

Principal investigator: dr hab. Jakub Mateusz Włodarczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

The effects of thyroid hormones in the brain in an animal model of depression

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii PAN

Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Justyna Józefa Brodowicz

Instytut Farmakologii PAN

Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Effect of co-treatment with fluoxetine and zinc in a chronic restraint stress (CRS) animal model of depression

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Paulina Misztak

Uniwersytet Jagielloński- Collegium Medicum

Synthesis and pharmacological characterization of structurally diverse chemical analogues of compound PO-10 as multiple ...

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Zagórska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Molecular mechanisms of lithium action in depression and mania: animal model and clinical study in bipolar disorder

Call: OPUS 11 , Panel: NZ5

Principal investigator: prof. Joanna Wiktoria Twarowska-Hauser

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Dariusz Marek Żurawek

Instytut Farmakologii PAN

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii PAN

Pessimism as cognitive biomarker of depression in animal model

Call: OPUS 7 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Molecular markers of stress resilience in animal model of depression

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii PAN

The molecular basis of stress-induced anxiety and affective disorders

Call: OPUS 2 , Panel: NZ2

Principal investigator: dr Michał Korostyński

Instytut Farmakologii PAN