Projects funded by the NCN

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86 projects found matching your search criteria :

  1. Hypoxia influence on human muscle stem cells genetically modified with proangiogenic factors: VEGF/FGF and PlGF.

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Agnieszka Joanna Zimna

    Instytut Genetyki Człowieka PAN

  2. Molecular basis of large rearrangements formation in the genes predisposing to the occurrence of intestinal polyposis

    Call: PRELUDIUM 5 , Panel: NZ5

    Principal investigator: Paweł Marcin Boruń

    Instytut Genetyki Człowieka PAN

  3. Global PUMILIO regulation of mRNAs and the role of MAELSTROM, a nuage component and a cancer testis marker, in human sem...

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: prof. Jadwiga Jaruzelska

    Instytut Genetyki Człowieka PAN

  4. Next-generation sequencing of miRNA transcriptome and functional in vitro study: towards unravelling pathomechanisms and...

    Call: OPUS 8 , Panel: NZ2

    Principal investigator: prof. Michał Witt

    Instytut Genetyki Człowieka PAN

  5. Genome-wide mutation screen of the regulome in laryngeal squamous cell carcinoma

    Call: OPUS 12 , Panel: NZ2

    Principal investigator: prof. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  6. Identification of novel oncogenic/tumor suppressive miRNA-mRNA interactions in pathogenesis of pediatric T-cell acute ly...

    Call: PRELUDIUM 13 , Panel: NZ2

    Principal investigator: Monika Drobna-Śledzińska

    Instytut Genetyki Człowieka PAN

  7. Genome-wide assessment of chromatin accessibility and sequence variants in non-coding regulatory elements in the pathoge...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: prof. Marzena Gajęcka

    Instytut Genetyki Człowieka PAN

  8. It takes two to tango_ a decryption of Marfan cardiomyopathy using human iPSC- derived cardiac cells and engineered hear...

    Call: OPUS 24 (LAP) , Panel: NZ3

    Principal investigator: dr hab. Natalia Rozwadowska

    Instytut Genetyki Człowieka PAN

  9. Analysis of the influence of selected compounds on the translational readthrough of premature termination codons in gene...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: prof. Ewa Maria Ziętkiewicz

    Instytut Genetyki Człowieka PAN

  10. Methylation and gene expression induced by interferon and ribavirin (TP53, BCL-2, PRKR, MxA and OAS) and the genotype, v...

    Call: OPUS 1 , Panel: NZ6

    Principal investigator: prof. Jacek Wysocki

    Instytut Genetyki Człowieka PAN

  11. Verification of the hypothesis of oxidative stress, apoptosis and immune factor as the mechanisms responsible for the po...

    Call: OPUS 10 , Panel: NZ5

    Principal investigator: dr hab. Monika Frączek

    Instytut Genetyki Człowieka PAN

  12. Role of miR-299-5p in pathogenesis of laryngeal squamous cell carcinoma.

    Call: PRELUDIUM 11 , Panel: NZ5

    Principal investigator: Joanna Janiszewska

    Instytut Genetyki Człowieka PAN

  13. The FAM13A silencing effect on lung cancer cells

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Iwona Ziółkowska-Suchanek

    Instytut Genetyki Człowieka PAN

  14. Unraveling altered 'eye-conic' cell dynamics and cell-cell interactions in keratoconus via bridged single-cell RNA seque...

    Call: PRELUDIUM 24 , Panel: NZ2

    Principal investigator: Alicja Wysocka

    Instytut Genetyki Człowieka PAN

  15. Complex cytogenetic and molecular analysis of sperm cells from chromosome translocation carriers (CT) with reproductive ...

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: prof. Maciej Krzysztof Kurpisz

    Instytut Genetyki Człowieka PAN

  16. Searching of sequence variants in mitochondrial genome, correlating with keratoconus phenotype in individuals from Polis...

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: dr Dorota Małgorzata Nowak

    Instytut Genetyki Człowieka PAN

  17. Human spermatogenesis in vitro model for study, diagnosis and treatment of male infertility

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: dr Natalia Rozwadowska

    Instytut Genetyki Człowieka PAN

  18. Novel causative genetic variants in azoospermia: whole genome analysis and functional in vitro studies

    Call: SONATA 13 , Panel: NZ5

    Principal investigator: dr Agnieszka Maria Malcher

    Instytut Genetyki Człowieka PAN

  19. In search for new genes involved in primary ciliary dyskinesia pathogenesis: functional screening of candidate genes usi...

    Call: PRELUDIUM 15 , Panel: NZ5

    Principal investigator: Alicja Małgorzata Rabiasz

    Instytut Genetyki Człowieka PAN

  20. NANOS1 RNP-interactome: structure and dynamics during specification/early stages of human germ cell development - signif...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: prof. Jadwiga Maria Jaruzelska

    Instytut Genetyki Człowieka PAN

  21. Czynniki genetyczne w dziecięcej ostrej białaczce limfoblastycznej z prekursorów limfocytów T (T-ALL): ocena wartości pr...

    Call: ETIUDA 5 , Panel: NZ5

    Principal investigator: Bronisława Maria Szarzyńska-Zawadzka

    Instytut Genetyki Człowieka PAN

  22. BCOR alterations and the activation of CXCL12 oncogenic pathway in classical Hodgkin lymphoma

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: prof. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  23. cfDNA methylome analysis in Hodgkin lymphoma patients

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Kinga Katarzyna Bednarek

    Instytut Genetyki Człowieka PAN

  24. Amino acid substitutions as the molecular basis for primary ciliary dyskinesia (PCD)

    Call: OPUS 25 , Panel: NZ2

    Principal investigator: prof. Ewa Maria Ziętkiewicz

    Instytut Genetyki Człowieka PAN

  25. Spatial visual transcriptomics approach of male and female gonad - validation of the role of candidate infertility genes...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr hab. Marta Anna Olszewska

    Instytut Genetyki Człowieka PAN

  26. Effect of heterozygous mutations and radiaton on expression of DNA repair genes- MRE11, RAD50 and NBN in the cells of ac...

    Call: OPUS 1 , Panel: NZ5

    Principal investigator: prof. Jerzy Stanisław Nowak

    Instytut Genetyki Człowieka PAN

  27. Sperm proteomic approach as the way to delineate a leading course of asthenozoospermia

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: prof. Maciej Kurpisz

    Instytut Genetyki Człowieka PAN

  28. Mutations of cis-regulatory elements as potential mechanism leading to chromatin inaccessibility and gene silencing in c...

    Call: PRELUDIUM 19 , Panel: NZ2

    Principal investigator: Adam Ustaszewski

    Instytut Genetyki Człowieka PAN

  29. Identification of genes responsible for the development of Sezary Syndrome by whole genome and transcriptome sequencing

    Call: HARMONIA 4 , Panel: NZ2

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka PAN

  30. Whole exome sequencing in Polish population of patients - search for the genetic basis of primary ciliary dyskinesia, PC...

    Call: OPUS 7 , Panel: NZ2

    Principal investigator: prof. Ewa Maria Ziętkiewicz

    Instytut Genetyki Człowieka PAN

  31. Functional analysis of novel oncomiR candidates in classical Hodgkin lymphoma

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: prof. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  32. Identification of mTOR pathway deregulation mechanisms alternative to mutations in T-cell acute lymphoblastic leukemia (...

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Natalia Maćkowska-Maślak

    Instytut Genetyki Człowieka PAN

  33. Methylome of corneal layers and topographic regions in keratoconus studied using Whole Genome Sequencing

    Call: PRELUDIUM 21 , Panel: NZ5

    Principal investigator: dr Katarzyna Jaśkiewicz-Rajewicz

    Instytut Genetyki Człowieka PAN

  34. Pharmacogenetics of thiopurine drugs in patients with inflammatory bowel disease - application of the newest methods of ...

    Call: SONATA 12 , Panel: NZ2

    Principal investigator: dr Marzena Skrzypczak-Zielińska

    Instytut Genetyki Człowieka PAN

  35. Identification and functional characterization of long non-coding RNAs involved in the ATM-dependent response to DNA dam...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

    Instytut Genetyki Człowieka PAN

  36. IREB2 and FAM13A as a chronic obstructive pulmonary disease and lung cancer susceptibility genes: genetic-association an...

    Call: SONATA 1 , Panel: NZ5

    Principal investigator: dr Iwona Maria Ziółkowska-Suchanek

    Instytut Genetyki Człowieka PAN

  37. FIBROdrive - just a passenger or the driver? Investigating the mechanism of the cardiac fibroblast influence on heart ti...

    Call: SONATA 14 , Panel: NZ3

    Principal investigator: dr Tomasz Jan Kolanowski

    Instytut Genetyki Człowieka PAN

  38. The survey of genes regulated by RBM protein family member - a component of splicing machinery in human spermatogenesis

    Call: PRELUDIUM BIS 1 , Panel: NZ5

    Principal investigator: dr hab. Natalia Rozwadowska

    Instytut Genetyki Człowieka PAN

  39. The role of DNA methylation in etiology of high myopia in Polish children

    Call: PRELUDIUM 18 , Panel: NZ5

    Principal investigator: dr Joanna Świerkowska-Janc

    Instytut Genetyki Człowieka PAN

  40. The expression analysis of genes and proteins potentially involved in lymph node metastasis formation in laryngeal cance...

    Call: OPUS 9 , Panel: NZ5

    Principal investigator: prof. Krzysztof Szyfter

    Instytut Genetyki Człowieka PAN

  41. Analysis of genetic factors associated with response to glucocorticoid in patient with inflammatory bowel disease

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: Marcin Gabryel

    Instytut Genetyki Człowieka PAN

  42. Role of LTR-driven circTNFRSF11A in the pathogenesis of classic Hodgkin lymphoma (cHL)

    Call: PRELUDIUM 23 , Panel: NZ2

    Principal investigator: Greta Nella Sawicz

    Instytut Genetyki Człowieka PAN

  43. The role of oral vitamin C supplementation in the epigenetic regulation of male fertility - finding the missing puzzles

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr hab. Monika Frączek

    Instytut Genetyki Człowieka PAN

  44. Establishing of a pyrosequencing pipeline for DNA methylation analysis.

    Call: SONATA 1 , Panel: NZ2

    Principal investigator: dr hab. Maciej Witold Giefing

    Instytut Genetyki Człowieka PAN

  45. Posttranscriptional control of putative cell cycle regulators SIAH1, SPINDLIN3 and TSC22D1 by PUMILIO2 protein in the hu...

    Call: OPUS 1 , Panel: NZ2

    Principal investigator: dr Barbara Ginter-Matuszewska

    Instytut Genetyki Człowieka PAN

  46. Genetically corrected autologous myogenic cells, associated with nanocapsules as the next generation formula for treatme...

    Call: OPUS 13 , Panel: NZ5

    Principal investigator: prof. Maciej Krzysztof Kurpisz

    Instytut Genetyki Człowieka PAN

  47. Elucidating the function of the transmembrane protein TMEM244 and its role in the development of lymphoid malignancies

    Call: OPUS 14 , Panel: NZ5

    Principal investigator: prof. Grzegorz Krzysztof Przybylski

    Instytut Genetyki Człowieka PAN

  48. BCL11b - Potential Therapeutic Target in T cell Neoplasms

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka PAN

  49. Cytoprotective role of antioxidants towards cells of myogenic origin in in vitro and in situ conditions

    Call: OPUS 7 , Panel: NZ3

    Principal investigator: prof. Maciej Krzysztof Kurpisz

    Instytut Genetyki Człowieka PAN

  50. A study of a potential role of NANOS proteins in orchestrating 3'UTR-mediated translational regulation of functionally r...

    Call: OPUS 8 , Panel: NZ1

    Principal investigator: dr Kamila Kusz-Zamelczyk

    Instytut Genetyki Człowieka PAN

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