Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effect of heterozygous mutations and radiaton on expression of DNA repair genes- MRE11, RAD50 and NBN in the cells of acute leukemias in children.

2011/01/B/NZ5/04322

Keywords:

MRE11 RAD50 NBN real time PCR gene expression radiation

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ1_1: Molecular biology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jerzy Nowak 

Number of co-investigators in the project: 2

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 383 500 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2014-05-31

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do elektroforezy (3 000 PLN)
  2. Zamrażarka (2 000 PLN)
  3. Automatyczne pipety (8 000 PLN)
  4. Lodówka (2 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations
    Authors:
    Jerzy Nowak, Bogna Świątek-Kościelna, Ewelina Maria Kałużna, Jolanta Rembowska, Agnieszka Dzikiewicz-Krawczyk, Mariola Zawada, Danuta Januszkiewicz-Lewandowska
    Academic press:
    Archives of Medical Science (rok: 2017, tom: 13, strony: 283-292), Wydawca: Termedia Publishing House
    Status:
    Published
    DOI:
    10.5114/aoms.2017.65452 - link to the publication