Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The expression analysis of genes and proteins potentially involved in lymph node metastasis formation in laryngeal cancer

2015/17/B/NZ5/00645

Keywords:

laryngeal cancer lymph node metastasis gene expression protein expression poor prognosis

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ5_9: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Krzysztof Szyfter 

Number of co-investigators in the project: 5

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 527 680 PLN

Project start date (Y-m-d): 2016-02-26

Project end date (Y-m-d): 2022-02-25

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Notebook.
  2. Aparat do PCR w czasie rzeczywistym (145 000 PLN)
  3. Urządzenie do analizy białek techniką Western blot.
  4. Aparatura do szybkiego transferu białek w technice Western blot.

Information in the final report

  • Publication in academic press/journals (2)
  1. Genetic signature and profiling of head and neck cancer: where do we stand?
    Authors:
    Paczkowska J, Szyfter K, Giefing M, Wierzbicka M.
    Academic press:
    Current Opinion in Otolaryngology & Head and Neck Surgery (rok: 2017, tom: Vol. 25 (2), strony: 154-158), Wydawca: Wolters Kluwer Health
    Status:
    Published
    DOI:
    10.1097/MOO.0000000000000348 - link to the publication
  2. Combined deletion and DNA methylation result in silencing of FAM107A gene in laryngeal tumors.
    Authors:
    Kiwerska K, Szaumkessel M, Paczkowska J, Bodnar M, Byzia E, Kowal E, Kostrzewska-Poczekaj M, Janiszewska J, Bednarek K, Jarmuż-Szymczak M, Kalinowicz E, Wierzbicka M, Grenman R, Szyfter K, Marszałek A, Giefing M.
    Academic press:
    Scientific Reports (rok: 2017, tom: 7, strony: 5386), Wydawca: Macmillan Publishers Limited, part of Nature Springer
    Status:
    Published
    DOI:
    10.1038/s41598-017-05857-1. - link to the publication