Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Global PUMILIO regulation of mRNAs and the role of MAELSTROM, a nuage component and a cancer testis marker, in human seminoma

2013/09/B/NZ1/01878

Keywords:

nuage MAELSTROM testis germ cell tumor PUMILIO

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_11: Other related subjects

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Genetyki Człowieka PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jadwiga Jaruzelska 

Number of co-investigators in the project: 4

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 1 440 162 PLN

Project start date (Y-m-d): 2014-03-14

Project end date (Y-m-d): 2018-09-13

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. wstrząsarka do mieszania roztworów (1 232 PLN)
  2. cytometr przepływowy (325 000 PLN)
  3. wirówka z jednym rotorem horyzontalnym 1.5-2.0ml oraz drugim na probówki 15 i 50ml (14 290 PLN)
  4. wysokonapięciowy zasilasz do do elektroforezy białek oraz wkład do transferu białek.
  5. Inkubator do podgrzewania mediów używanych do hodowli komórkowych (7 326 PLN)
  6. mikroskop odwrócony z zieloną fluorescencją (48 294 PLN)
  7. pH-metr (2 200 PLN)
  8. aparat do elektroforezy.
  9. notebook z oprogramowaniem.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Kinesin KIF18A is a novel PUM-regulated target promoting mitotic progression and survival of a human male germ cell line
    Authors:
    Maciej Jerzy Smialek1, Bogna Kuczynska, Erkut Ilaslan, Damian Mikolaj Janecki, Marcin Piotr Sajek, Kamila Kusz-Zamelczyk and Jadwiga Jaruzelska
    Academic press:
    Journal of Cell Science (rok: 2020, tom: 133, strony: 45299), Wydawca: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/jcs.240986 - link to the publication
  2. SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma
    Authors:
    Damian Mikolaj Janecki, Marcin Sajek, Maciej Jerzy Smialek, Maciej Kotecki, Barbara Ginter-Matuszewska, Bogna Kuczynska, Anna Spik, Tomasz Kolanowski, Riko Kitazawa, Maciej Kurpisz, and Jadwiga Jaruzelska
    Academic press:
    Oncotarget (rok: 2018, tom: 9, strony: 32466-32477), Wydawca: Impact Journals
    Status:
    Published
    DOI:
    10.18632/oncotarget.25977 - link to the publication
  3. Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model
    Authors:
    Maciej Jerzy Smialek, Erkut Ilaslan, Marcin Sajek, Aleksandra Swiercz, Damian Mikolaj Janecki, Kamila Kusz-Zamelczyk, Tomasz Wozniak, Maciej Kotecki, Luiza Handschuh, Marek Figlerowicz and Jadwiga Jaruzelska
    Academic press:
    Cells (rok: 2020, tom: 16, strony: 45314), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9040984 - link to the publication
  1. Bioinformatic construction of PUM1 and PUM2 RNA-regulons in TCam-2 cell line
    Authors:
    Maciej J. Smialek, Marcin Sajek, Aleksandra Swiercz, Erkut Ilaslan, Damian M. Janecki, Maciej Kotecki, Kamila Kusz-Zamelczyk, Tomasz Wozniak, Luiza Handschuh, Marek Figlerowicz and Jadwiga Jaruzelska
    Conference:
    BIO3rd PtBioch 2018 Gdańsk (rok: 2018, ), Wydawca: Polskie Towarzystwo Biochemiczne i Komitet Biochemii i Biofizyki PAN
    Data:
    konferencja 18-21 wrzesień
    Status:
    Published