Search results

151. Strategies to improve the efficacy of NK cells in targeting aggressive B-cell lymphomas

Principal investigator: dr Małgorzata Bobrowicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: WEAVE-UNISONO, Panel: NZ6

152. The role of free fatty acid receptors in pathophysiology of the functional gastrointestinal tract disorders: new therapi…

Principal investigator: dr hab. Maciej Stanisław Sałaga

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM BIS 5, Panel: NZ7

153. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design…

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 22, Panel: NZ7

154. Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo…

Principal investigator: dr Alicja Małgorzata Braczko

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ5

155. Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

Principal investigator: dr hab. Angelika Muchowicz

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 25, Panel: NZ6

156. Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for …

Principal investigator: dr hab. Monika Bzowska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

Call: OPUS 25, Panel: NZ6

157. Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun…

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM BIS 4, Panel: NZ6

158. Gaining control on XBP1s signaling as a starting point for novel cancer therapies

Principal investigator: prof. Rafał Artur Bartoszewski

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 24, Panel: NZ7

159. Design and implementation of effective cOmbination of Phages and Antibiotics for improved TheRApy protocols against KLEb…

Principal investigator: prof. Zuzanna - Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: JPIAMR ACTION Call 2022, Panel: NZ6

160. Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

Principal investigator: Dawid Dariusz Dorna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM 21, Panel: NZ7

161. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies…

Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

Instytut Chemii Bioorganicznej PAN

Call: OPUS 23, Panel: NZ7

162. Anti-inflammatory effect of senotherapeutic agents on gingival fibroblasts as a potential therapy for periodontitis

Principal investigator: Alicja Danuta Płonczyńska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 21, Panel: NZ5

163. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi…

Principal investigator: prof. Krzysztof Tomasz Kamiński

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 23, Panel: NZ7

164. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st…

Principal investigator: dr Bartłomiej Pochwat

Instytut Farmakologii PAN

Call: SONATA 17, Panel: NZ7

165. Targeting UDP-glucose and P2Y14 receptor interaction for therapeutic modulation of inflammatory lung diseases

Principal investigator: dr Tadeusz Piotr Karcz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

166. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a…

Principal investigator: dr hab. Dorota Justyna Łażewska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 22, Panel: NZ7

167. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

Principal investigator: dr hab. Anna Wardowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 22, Panel: NZ7

168. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami…

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

169. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Call: SONATA 17, Panel: NZ5

170. The role of intestinal CYP2E1 in pathophysiology of the gastrointestinal tract disorders: new therapies for leaky gut sy…

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

Call: PRELUDIUM BIS 3, Panel: NZ7

171. Investigation of the MLK4 biology in breast cancer and search for new therapeutic strategies using innovative PROTAC com…

Principal investigator: dr Anna Agnieszka Marusiak

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: SONATA BIS 11, Panel: NZ5

172. RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized…

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM 20, Panel: NZ7

173. Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor…

Principal investigator: prof. Barbara Malinowska

Uniwersytet Medyczny w Białymstoku

Call: OPUS 21, Panel: NZ7

174. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent…

Principal investigator: Olga Ciupak

Politechnika Gdańska, Wydział Chemiczny

Call: PRELUDIUM 20, Panel: NZ7

175. New 3-methoxypropanamide derivatives in search of effective substances for the treatment of neurological diseases - epil…

Principal investigator: Marcin Konrad Jakubiec

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 20, Panel: NZ7

176. Normalization of energy metabolism as a way to develop innovative antithrombotic therapies

Principal investigator: dr Patrycja Kaczara

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: OPUS 21, Panel: NZ7

177. Addressing the brain glioma temozolomide therapy limitations

Principal investigator: dr hab. Joanna Małgorzata Lewandowska-Łańcucka

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 21, Panel: NZ7

178. Mechanisms involved in heme acquisition - potential targets for therapies directed towards reduction of Porphyromonas gi…

Principal investigator: dr Michał Sylwester Śmiga

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 21, Panel: NZ6

179. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search…

Principal investigator: prof. Marcin Roman Kołaczkowski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 21, Panel: NZ7

180. Supporting a therapy of non-healing wounds with witch hazel bark

Principal investigator: Karolina Anna Pawłowska

Warszawski Uniwersytet Medyczny

Call: PRELUDIUM 20, Panel: NZ7

181. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha…

Principal investigator: dr Dawid Marcin Panek

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 21, Panel: NZ7

182. Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera…

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: WEAVE-UNISONO, Panel: NZ7

183. MicroRNAome maturation control and its application in selective targeting of cancer stem cells

Principal investigator: dr Jakub Godlewski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 20, Panel: NZ5

184. Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modi…

Principal investigator: prof. Tomasz Jacek Sarnowski

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: NZ5

185. Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

Principal investigator: dr hab. Magdalena Hanna Winiarska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM BIS 2, Panel: NZ6

186. Targeting deregulated expression of anti-apoptotic proteins belonging to the Bcl-2 family in macrophages as a potential …

Principal investigator: dr Maja Anna Sochalska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA 16, Panel: NZ5

187. New therapies of opioid use disorder

Principal investigator: dr Wojciech Barnaba Solecki

Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

Call: OPUS 20, Panel: NZ7

188. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br…

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii PAN

Call: SONATA 16, Panel: NZ7

189. Long noncoding RNA - new aim of anti-influenza therapy

Principal investigator: dr Marta Soszyńska-Jóźwiak

Instytut Chemii Bioorganicznej PAN

Call: SONATA 16, Panel: NZ6

190. Immunogenicity of plant-produced chimeric Virus-Like Particles formed byHBcAg displaying HBsAg epitopes for potential th…

Principal investigator: dr Benita Ortega Berlanga

Instytut Genetyki Roślin PAN

Call: POLS, Panel: NZ7

191. Understanding of human insulin maturation for cell and gene therapy in diabetes

Principal investigator: dr hab. Małgorzata Borowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 19, Panel: NZ3

192. Atopic Dermatitis - searching for new strategic points of treatment, by evaluating clinical and prognostic significance …

Principal investigator: Anna Maria Zaryczańska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: PRELUDIUM 19, Panel: NZ5

193. Immune response induced by injection-oral co-immunisation with plant-derived HBV antigens polarising the response to Th1…

Principal investigator: prof. Tomasz Jan Pniewski

Instytut Genetyki Roślin PAN

Call: OPUS 19, Panel: NZ6

194. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

195. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

Principal investigator: Marek Andrzej Jamrozik

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

196. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc…

Principal investigator: Alicja Aleksandra Gawalska

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

197. Application of small compounds in the epigenetic therapy of malignant brain gliomas

Principal investigator: prof. Mirosława Zofia Naskręt-Barciszewska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 19, Panel: NZ5

198. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system…

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: SONATINA 4, Panel: NZ7

199. Investigation on PD-L1 biology for precise shaping of anticancer adoptive therapies

Principal investigator: dr Agnieszka Graczyk-Jarzynka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 15, Panel: NZ6

200. The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

Principal investigator: prof. Agnieszka Piekiełko-Witkowska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Szkoła Nauk Medycznych

Call: OPUS 18, Panel: NZ5

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