Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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MicroRNAome maturation control and its application in selective targeting of cancer stem cells

2020/39/B/NZ5/02893

Keywords:

non-coding RNA circular RNA microRNA cancer stem cells cell differentiation

Descriptors:

  • NZ5_003:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jakub Godlewski 

Number of co-investigators in the project: 4

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 2 987 254 PLN

Project start date (Y-m-d): 2021-08-24

Project end date (Y-m-d): 2025-08-23

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response
    Authors:
    Arpita Balakrishnan, Gabriela Winiarek, Olga Hołówka , Jakub Godlewski, Agnieszka Bronisz
    Academic press:
    Frontiers in Immunology (rok: 2025, tom: 16, strony: 1540431), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2025.1540431 - link to the publication
  2. The Mechanism of the Neuroprotective Effect of Kynurenic Acid in the Experimental Model of Neonatal Hypoxix-Ischemia: The Link to Oxidative Stress
    Authors:
    Ewelina Bratek-Gerej, Apolonia Ziembowicz, Jakub Godlewski, Elzbieta Salinska
    Academic press:
    Antioxidants (rok: 2021, tom: 10(11), strony: 1775), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox10111775 - link to the publication
  3. Hyperbaric oxygen therapy for the treatment of hypoxic/ischemic injury upon perinatal asphyxia—are we there yet?
    Authors:
    Damian Mielecki, Jakub Godlewski, Elzbieta Salinska
    Academic press:
    Frontiers in Neurology (rok: 2024, tom: 15, strony: 1386695), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fneur.2024.1386695 - link to the publication
  4. MiR-128-3p - a gray eminence of the human central nervous system.
    Authors:
    Klaudia Kiel , Sylwia Katarzyna Król , Agnieszka Bronisz , Jakub Godlewski
    Academic press:
    Mol Ther Nucleic Acids. (rok: 2024, tom: 35(1), strony: 102141), Wydawca: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.omtn.2024.102141 - link to the publication
  5. Circular RNAs—New Kids on the Block in Cancer Pathophysiology and Management
    Authors:
    Adrian Szczepaniak, Agnieszka Bronisz, and Jakub Godlewski
    Academic press:
    Cells (rok: 2023, tom: 12(4), strony: 552), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12040552 - link to the publication