Search results

451. Drug repurposing to target p53 protein family for improved therapy in the relapsed TP53 and EGFR mutated lung cancer

Principal investigator: dr hab. Alicja Elżbieta Chrzanowska

Warszawski Uniwersytet Medyczny

Call: OPUS 20, Panel: NZ7

452. Cleavable molecular nanocarrier:antimetabolite conjugates of antimicrobial activity

Principal investigator: prof. Sławomir Piotr Milewski

Politechnika Gdańska, Wydział Chemiczny

Call: OPUS 20, Panel: ST4

453. Polymersomes specifically releasing cGAMP and doxorubicin in tumor hypoxic regions as a new anti-cancer therapeutic stra…

Principal investigator: dr hab. Ryszard Smolarczyk

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: OPUS 20, Panel: NZ5

454. Pulse electroporation as an innovative method in the process of the so-called root milking", use in the adaptation of me…

Principal investigator: dr Sylwester Ślusarczyk

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: SONATA 16, Panel: NZ9

455. The mechanisms of mitochondrial damage-dependent neuroinflammation in experimental models of Parkinson's disease. The ro…

Principal investigator: prof. Agata Adamczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 20 (LAP), Panel: NZ4

456. Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity.

Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

Instytut Biologii Medycznej PAN

Call: OPUS 20, Panel: NZ7

457. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

Principal investigator: prof. Małgorzata Kucińska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA 16, Panel: NZ7

458. New therapies of opioid use disorder

Principal investigator: dr Wojciech Barnaba Solecki

Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

Call: OPUS 20, Panel: NZ7

459. Systems of polyphenols with prebiotic carriers as combinations with unknown potential of biological activity

Principal investigator: prof. Judyta Agnieszka Cielecka-Piontek

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM BIS 2, Panel: NZ7

460. Recording and modulation of high frequency neurophysiological activities underlying encoding and recall of human memory.

Principal investigator: dr Michał Tomasz Kucewicz

Politechnika Gdańska

Call: OPUS 20 (LAP), Panel: NZ4

461. Inter-strain chimeric mice to study the role of the placenta in the pathogenesis of neurodevelopmental disorders

Principal investigator: dr Silvestre Sampino

Instytut Genetyki i Hodowli Zwierząt PAN

Call: OPUS 20, Panel: NZ4

462. Real-time imaging of dopamine release and neuronal populations dynamics in the motor cortex of awake mice – decoding of …

Principal investigator: dr Przemysław Eligiusz Cieślak

Uniwersytet Jagielloński, Wydział Biologii

Call: SONATA 16, Panel: NZ4

463. Mucoadhesive delivery systems of polyphenols as an effective way to increase their health-promoting properties

Principal investigator: dr hab. Magdalena Paczkowska-Walendowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: SONATA 16, Panel: NZ7

464. Interactions of plant extracts traditionally used in skin diseases with a human skin microbiota

Principal investigator: prof. Sebastian Granica

Warszawski Uniwersytet Medyczny

Call: PRELUDIUM BIS 2, Panel: NZ7

465. The influence of natural plant extracts obtained by supercritical extraction on the replication inhibition of the most i…

Principal investigator: prof. Grzegorz Jan Woźniakowski

Uniwersytet Mikołaja Kopernika

Call: OPUS 20, Panel: NZ7

466. Development of an in vitro model for the evaluation of phototoxicity of drugs with different affinity to melanin using a…

Principal investigator: dr hab. Jakub Rok

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

Call: SONATA 16, Panel: NZ7

467. New approach for neuronal regeneration and survival following ischemic stroke - gene therapy based on MEF2A repression u…

Principal investigator: dr Malwina Anna Lisek

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Call: SONATA 16, Panel: NZ4

468. Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi…

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

Call: SONATA 16, Panel: NZ7

469. Understanding the regulation of GDF11 signaling in the context of the gastrointestinal diseases

Principal investigator: dr hab. Marta - Zielińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM BIS 2, Panel: NZ7

470. Coming together - neural dynamics of transition from out-group reserve to in-group fellowship

Principal investigator: dr Alicja Puścian

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA 16, Panel: NZ4

471. Neuronal basis of spatial choice.

Principal investigator: dr hab. Katarzyna Anna Radwańska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: MAESTRO 12, Panel: NZ4

472. Identifying unique adaptive responses of red pulp macrophages to iron deficiency

Principal investigator: dr Katarzyna Maria Mleczko-Sanecka

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA BIS 10, Panel: NZ4

473. The role of MOTS-c peptide in the regulation of adrenal cortex physiological function

Principal investigator: prof. Marcin Michał Ruciński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: SONATA BIS 10, Panel: NZ4

474. Electroporation-based manipulation of drug resistance in cancer using novel nanosecondasymmetrical pulse sequences

Principal investigator: dr hab. Julita Kulbacka

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

Call: DAINA 2, Panel: NZ7

475. Strategies to increase the performance of skeletal muscles and brown adipose tissue to combat obesity and related diseas…

Principal investigator: dr hab. Grzegorz Piotr Sumara

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA BIS 10, Panel: NZ4

476. Application of metabolomics to study the mechanisms of statin treatment side effecs manifested by muscle pain.

Principal investigator: dr Ewa Paszkowska

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 19, Panel: NZ4

477. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl…

Principal investigator: dr Przemysław Patryk Zaręba

Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

Call: PRELUDIUM 19, Panel: NZ7

478. A tissue engineering platform for precision cancer medicine and chemosensitivity testing in head and neck squamous cell …

Principal investigator: prof. Matthias Nees

Uniwersytet Medyczny w Lublinie

Call: OPUS 19, Panel: NZ4

479. Modulation of the injured nerve microenvironment to support axon regeneration and spinal cord motoneuron survival - mole…

Principal investigator: dr hab. Małgorzata Zofia Zawadzka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 19, Panel: NZ4

480. Microenvironment dependent disruption of tumor capillaries using diamond nanoparticles in treatment of highly vasculariz…

Principal investigator: dr hab. Mateusz Krzysztof Wierzbicki

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: OPUS 19, Panel: NZ7

481. Molecular and ultrastructural changes in neuromuscular junction after complete spinal cord transection and spinal BDNF o…

Principal investigator: Anna Ida Głowacka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 19, Panel: NZ4

482. Astrocytes-regulated oligomerization state of fructose bisphosphatase 2 (FBP2) in neurons as a basic factor regulating m…

Principal investigator: prof. Dariusz Stanisław Rakus

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 19, Panel: NZ4

483. Drug metabolizing enzymes (DMEs) in liver pathology, proteomic characteristics, transcriptional and epigenetic regulatio…

Principal investigator: prof. Marek Droździk

Pomorski Uniwersytet Medyczny w Szczecinie

Call: OPUS 19, Panel: NZ7

484. Ionotropic gelation and chemical crosslinking as tools to obtain matrix capsules with mesalazine

Principal investigator: dr Piotr Gadziński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM 19, Panel: NZ7

485. Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

Principal investigator: dr Olga Iga Wronikowska-Denysiuk

Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

Call: PRELUDIUM 19, Panel: NZ7

486. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

Principal investigator: prof. Krystyna Czesława Gołembiowska

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

487. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the …

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

Call: OPUS 19, Panel: NZ7

488. Schisandra henryi C.B. Clarke - increasing the production of secondary metabolites by biotechnological methods, and eval…

Principal investigator: Karolina Anna Jafernik

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

489. Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Principal investigator: Agnieszka Agata Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: PRELUDIUM 19, Panel: NZ5

490. In vivo and ex vivo tracking the cocaine's mechanism of action in the medial part of the central amygdala

Principal investigator: Łukasz Damian Bijoch

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 19, Panel: NZ4

491. The effect of methylated resveratrol analogue 3,4,4',5-tetramethoxystilbene (DMU-212) on secretion profile and different…

Principal investigator: Małgorzata Józkowiak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: PRELUDIUM 19, Panel: NZ7

492. Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic…

Principal investigator: dr hab. Janusz Marcin Dąbrowski

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 19, Panel: NZ7

493. The role of the metastatic liver niche in the uveal melanomaradioresistance

Principal investigator: dr hab. Martyna Elas

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 19, Panel: NZ4

494. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

495. Exploring the mechanisms of therapy-facilitated metastasis and CAAX proteins-processing enzymes in liver cancer

Principal investigator: dr Jarosław Marek Cisowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 19, Panel: NZ4

496. Assessment of the ability of application of folic acid and/or transferrin as alinkers between conjugates of quantum dots…

Principal investigator: Joanna Pilch

Politechnika Gdańska

Call: PRELUDIUM 19, Panel: NZ7

497. The role of the physical exercise and skeletal muscle-adipose tissue crosstalk in the development of experimental Barret…

Principal investigator: prof. Tomasz Michał Brzozowski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 19, Panel: NZ4

498. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

Principal investigator: Marek Andrzej Jamrozik

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

499. Validation of a new mouse model for autism spectrum disorder research

Principal investigator: dr hab. Marta Barbara Wiśniewska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 19, Panel: NZ4

500. Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: POLS, Panel: NZ4

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