Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Microenvironment dependent disruption of tumor capillaries using diamond nanoparticles in treatment of highly vascularized tumors

2020/37/B/NZ7/03532

Keywords:

microenvironment tumor vascularization angiogenesis diamond nanoparticles

Descriptors:

  • NZ7_015:
  • NZ7_016:
  • NZ7_014:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mateusz Krzysztof Wierzbicki 

Number of co-investigators in the project: 7

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 1 584 720 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2026-01-31

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Effects of Metallic and Carbon-Based Nanomaterials on Human Pancreatic Cancer Cell Lines AsPC-1 and BxPC-3
    Authors:
    Wójcik, B.; Sawosz, E.; Szczepaniak, J.; Strojny, B.; Sosnowska, M.; Daniluk, K.; Zielińska-Górska, M.; Bałaban, J.; Chwalibog, A.; Wierzbicki, M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22,, strony: 12100), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212100 - link to the publication
  2. Dependence of diamond nanoparticle cytotoxicity on physicochemical parameters: comparative studies of glioblastoma, breast cancer, and hepatocellular carcinoma cell lines
    Authors:
    Barbara Wójcik, Katarzyna Zawadzka, Sławomir Jaworski, Marta Kutwin, Malwina Sosnowska, Agnieszka Ostrowska, Marta Grodzik, Artur Małolepszy, Marta Mazurkiewicz-Pawlicka, Mateusz Wierzbicki
    Academic press:
    Nanotoxicology (rok: 2023, tom: 17, strony: 310-337), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/17435390.2023.2218925 - link to the publication
  3. Effects of Metallic and Carbon-Based Nanomaterials on Human Pancreatic Cancer Cell Lines AsPC-1 and BxPC-3
    Authors:
    Wójcik, B.; Sawosz, E.; Szczepaniak, J.; Strojny, B.; Sosnowska, M.; Daniluk, K.; Zielińska-Górska, M.; Bałaban, J.; Chwalibog, A.; Wierzbicki, M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22,, strony: 12100), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212100 - link to the publication
  4. Effects of Metallic and Carbon-Based Nanomaterials on Human Pancreatic Cancer Cell Lines AsPC-1 and BxPC-3
    Authors:
    Wójcik, B.; Sawosz, E.; Szczepaniak, J.; Strojny, B.; Sosnowska, M.; Daniluk, K.; Zielińska-Górska, M.; Bałaban, J.; Chwalibog, A.; Wierzbicki, M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22,, strony: 12100), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212100 - link to the publication
  5. Differences in the cell type-specific toxicity of diamond nanoparticles to endothelial cells depending on the exposure of the cells to nanoparticles
    Authors:
    Mateusz Wierzbicki, Katarzyna Zawadzka, Barbara Wójcik, Sławomir Jaworski, Barbara Strojny, Agnieszka Ostrowska, Artur Małolepszy, Marta Mazurkiewicz-Pawlicka, Ewa Sawosz
    Academic press:
    International Journal of Nanomedicine (rok: 2023, tom: 18, strony: 2821—2838), Wydawca: Dovpress
    Status:
    Published
    DOI:
    10.2147/IJN.S411424 - link to the publication
  6. Differences in the cell type-specific toxicity of diamond nanoparticles to endothelial cells depending on the exposure of the cells to nanoparticles
    Authors:
    Mateusz Wierzbicki, Katarzyna Zawadzka, Barbara Wójcik, Sławomir Jaworski, Barbara Strojny, Agnieszka Ostrowska, Artur Małolepszy, Marta Mazurkiewicz-Pawlicka, Ewa Sawosz
    Academic press:
    International Journal of Nanomedicine (rok: 2023, tom: 18, strony: 2821—2838), Wydawca: Dovpress
    Status:
    Published
    DOI:
    10.2147/IJN.S411424 - link to the publication
  7. Cell Line-Dependent Adhesion and Inhibition of Proliferation on Carbon-Based Nanofilms
    Authors:
    Barbara Wójcik, Katarzyna Zawadzka, Ewa Sawosz, Malwina Sosnowska, Agnieszka Ostrowska, Mateusz Wierzbicki
    Academic press:
    Nanotechnology, Science and Applications (rok: 2023, tom: 16, strony: 41-47), Wydawca: Dovepress
    Status:
    Published
    DOI:
    10.2147/nsa.s439185 - link to the publication
  8. Dependence of diamond nanoparticle cytotoxicity on physicochemical parameters: comparative studies of glioblastoma, breast cancer, and hepatocellular carcinoma cell lines
    Authors:
    Barbara Wójcik, Katarzyna Zawadzka, Sławomir Jaworski, Marta Kutwin, Malwina Sosnowska, Agnieszka Ostrowska, Marta Grodzik, Artur Małolepszy, Marta Mazurkiewicz-Pawlicka, Mateusz Wierzbicki
    Academic press:
    Nanotoxicology (rok: 2023, tom: nd, strony: nd), Wydawca: Taylor & Francis
    Status:
    Accepted for publication

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