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1. Evaluation of the efficiency of Spindle Assembly Checkpoint during mouse oocyte meiosis

Principal investigator: dr hab. Zbigniew Piotr Polański

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

Call: OPUS 1, Panel: NZ3

2. Strategy to overcome the "ionic checkpoint" and improve the antitumor immunotherapy.

Principal investigator: dr Beata Pyrzyńska

Warszawski Uniwersytet Medyczny

Call: OPUS 29, Panel: NZ7

3. Multiparameter analysis of co-inhibitory and co-stimulatory immune checkpoints and their role in the induction of immuno…

Principal investigator: dr Dorota Suszczyk

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 22, Panel: NZ6

4. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit…

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Call: SONATA 18, Panel: NZ7

5. Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

Principal investigator: dr Katarzyna Magiera-Mularz

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 22, Panel: NZ7

6. The role of the immune checkpoints in the pathomechanism of depressive disorders.

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

Call: OPUS 22, Panel: NZ6

7. The immune checkpoints in non-small cell lung cancer - research on genetic and epigenetic mechanism regulating mRNA and …

Principal investigator: dr hab. Monika Jasek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: OPUS 17, Panel: NZ5

8. Structural and functional analysis of immune checkpoints

Principal investigator: prof. Grzegorz Dubin

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: OPUS 13, Panel: NZ1

9. The role of arginase-1 in antitumor efficacy of cancer immunotherapy using checkpoint inhibitors

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: OPUS 12, Panel: NZ6

10. Dual cell cycle blockade and immune checkpoint inhibition as a potential strategy of sequential anticancer therapy

Principal investigator: Alicja Stanisława Słota

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ7

11. Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors…

Principal investigator: dr Radosław Dariusz Kitel

Uniwersytet Jagielloński

Call: SONATA 20, Panel: ST5

12. Heterogeneity immunocompetent cells during chimeric antigen receptor T cell (CAR-T) CD19 immunotherapy.

Principal investigator: Aleksandra Maria Oszer

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 22, Panel: NZ6

13. Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu…

Principal investigator: prof. Maria Anna Kowalska

Instytut Biologii Medycznej PAN

Call: OPUS 24, Panel: NZ5

14. Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne…

Principal investigator: Katarzyna Joanna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Call: PRELUDIUM 21, Panel: NZ1

15. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

Principal investigator: dr hab. Anna Wardowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 22, Panel: NZ7

16. Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro…

Principal investigator: dr Łukasz Dariusz Skalniak

Uniwersytet Jagielloński, Wydział Chemii

Call: SONATA BIS 11, Panel: NZ7

17. Novel factors involved in cell cycle control after DNA damage.

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 21, Panel: NZ1

18. The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

Principal investigator: Magdalena Maria Żarnik

Uniwersytet Jagielloński, Wydział Chemii

Call: PRELUDIUM 20, Panel: ST4

19. The clinical significance of immunosuppression in ovarian cancer microenvironments

Principal investigator: dr Anna Maria Pawłowska-Łachut

Uniwersytet Medyczny w Lublinie

Call: PRELUDIUM 20, Panel: NZ6

20. Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t…

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 20, Panel: NZ4

21. Development of a three-dimensional in vitro model for studying the mechanisms of immunostimulatory activity of PD-1/PD-L…

Principal investigator: Justyna Natalia Kocik-Król

Uniwersytet Jagielloński, Wydział Chemii

Call: PRELUDIUM 18, Panel: NZ5

22. Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

Principal investigator: dr Marta Marcelina Spodzieja

Uniwersytet Gdański, Wydział Chemii

Call: SONATA 13, Panel: ST5

23. Guardian of a cell cycle: role of HO-1 in HSC proliferation

Principal investigator: Monika Żukowska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 13, Panel: NZ1

24. Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 12, Panel: NZ6

25. Genotoxicity of antitumor compound 3-bromopyruvate in the yeast Saccharomyces cerevisiae.

Principal investigator: dr Magdalena Cal

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 9, Panel: NZ2

26. Identification of Saccharomyces cerevisiae genes maintaining cell diploidy and genome stability

Principal investigator: dr hab. Adrianna Martyna Skoneczna

Instytut Biochemii i Biofizyki PAN

Call: OPUS 2, Panel: NZ2

27. MAP kinase signaling pathway in response to replication stress and DNA damage in root meristem cells of Vicia faba

Principal investigator: Konrad Szczepan Winnicki

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska; Katedra Cytofizjologii

Call: PRELUDIUM 1, Panel: NZ3

28. Genotoxicity of arsenic in the yeast Saccharomyces cerevisiae

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: PRELUDIUM 1, Panel: NZ2

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