The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists
2021/41/N/ST4/03485
Keywords
Descriptors
- ST4_008: Chemia organiczna
- ST4_009: Chemia biologiczna
- ST4_003: Struktura i architektura molekularna
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Uniwersytet Jagielloński, Wydział Chemii
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 20 – announced on 2021-03-15
- Amount awarded
- 139 710 PLN
- Project start date
- 2022-02-03
- Project end date
- 2024-02-02
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Exploring the Surface of the Ectodomain of the PD-L1 Immune Checkpoint with Small-Molecule Fragments
- Authors:
- Radoslaw Kitel, Ismael Rodríguez, Xabier del Corte, Jack Atmaj, Magdalena Żarnik, Ewa Surmiak, Damian Muszak, Katarzyna Magiera-Mularz, Grzegorz M. Popowicz, Tad A. Holak, and Bogdan Musielak*
- Academic press:
- ACS Chemical Biology (year: 2022, volume: 17, pages: 2655-2663), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/acschembio.2c00583 – link to the publication