Structural and functional analysis of immune checkpoints
2017/25/B/NZ1/00827
Keywords
Descriptors
- NZ1_1: Biologia molekularna
- NZ1_4: Biologia strukturalna
- NZ3_1: Biologia komórki
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 13 – announced on 2017-03-15
- Amount awarded
- 1 923 600 PLN
- Project start date
- 2018-01-26
- Project end date
- 2022-09-25
- Project duration
- 56 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Dysk zewnętrzny 2 szt..
- Inkubator do hodowli komórek. Cost: 35 000 PLN
Information in the final report
Publication in academic press/journals (4)
-
Macrocyclic Peptide Inhibitor of PD‐1/PD‐L1 Immune Checkpoint
- Authors:
- Magiera‐Mularz, K., Kuska, K., Skalniak, L., Grudnik, P., Musielak, B., Plewka, J., Kocik, J., Stec, M., Weglarczyk, K., Sala, D., Wladyka, B., Siedlar, M., Holak, T.A., Dubin, G.
- Academic press:
- Advanced Therapeutics (year: 2021, volume: 4:(2), pages: 2000195 (1-6)), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1002/adtp.202000195 – link to the publication
-
Imaging of Clear Cell Renal Carcinoma with Immune Checkpoint Targeting Aptamer-Based Probe
- Authors:
- Malicki, S., Pucelik, B., Zyla, E., Benedyk-Machaczka, M., Galan, W., Golda A., Sochaj-Gregorczyk, A., Kaminska, M., Encarnacao, J.C., Chruscicka, B., Marti, H.-P., Chen, T.J., Magiera-Mularz, K., Zieba, B., Holak, T.A., Dabrowski, J.M., Czarna, A., Koziel, J., Mydel, P., Dubin, G.
- Academic press:
- Pharmaceuticals (year: 2022, volume: 15, pages: 687), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ph15060697 – link to the publication
-
Ultrasensitive electrochemical determination of the cancer biomarker protein sPD-L1 based on a BMS-8-modified gold electrode
- Authors:
- Niedziałkowski, P., Bojko, M., Ryl, J., Wcisło, A., Spodzieja, M., Magiera-Mularz, K., Guzik, K., Dubin, G., Holak, T., Ossowski, T., Rodziewicz-Motowidło, S.
- Academic press:
- Bioelectrochemistry (year: 2021, volume: 139, pages: 107742), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.bioelechem.2021.107742 – link to the publication
-
Structural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis
- Authors:
- Zyla, E., Musielak, B., Holak, T.A., Dubin, G.
- Academic press:
- Molecules (year: 2021, volume: 26, pages: 4848), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules26164848 – link to the publication