Projects funded by the NCN

Exploring the mechanisms of therapy-facilitated metastasis and CAAX proteins-processing enzymes in liver cancer

Call: OPUS 19 , Panel: NZ4

Principal investigator: dr Jarosław Marek Cisowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Validation of a new mouse model for autism spectrum disorder research

Call: OPUS 19 , Panel: NZ4

Principal investigator: dr hab. Marta Barbara Wiśniewska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Mechanism of regulation glycosaminoglycan levels by resveratrol in a mouse model of a neuronopathic disease from the muc...

Call: PRELUDIUM 18 , Panel: NZ2

Principal investigator: Estera Elmira Rintz

Uniwersytet Gdański, Wydział Biologii

Evaluation of the activity of MDM2-p53 antagonist RG7388 in mouse cancer models, alone and in combination with anti-PD-1...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Aneta Sylwia Nieznańska

Uniwersytet Jagielloński, Wydział Chemii

Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Justyna Beata Barut

Instytut Farmakologii PAN

Effect of Embryonic Diapause on mitochondrial mutations inheritance in the mouse model of obesity.

Call: PRELUDIUM 18 , Panel: NZ3

Principal investigator: Łukasz Józef Gąsior

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

The role of utrophin in cardiomyopathy in Duchenne muscular dystrophy

Call: PRELUDIUM 17 , Panel: NZ3

Principal investigator: dr Kalina Andrysiak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Research of a new small-molecule 1,2,4-triazine derivative (MM-129) - assessment of anti-neoplastic activity and safety ...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Dariusz Alfred Pawlak

Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Evaluation of tumour metabolomic response to imatinib in a study of mouse xenograft models with gastrointestinal stromal...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Szymon Macioszek

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

The impact of gut microbiota from extremely obese humans on the progression of metabolic syndrome in mouse models

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Jerzy Zygmunt Ostrowski

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Ultrastructure of hair cells of the organ of Corti and the effects of minocycline on responses to acustic stimulation in...

Call: OPUS 14 , Panel: NZ4

Principal investigator: dr hab. Magdalena Kinga Dziembowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

The role of RAGE, receptor for advanced glycation end-products, in the progressive spinal motor neuron degeneration in f...

Call: OPUS 13 , Panel: NZ4

Principal investigator: prof. Joanna Alicja Wojtkiewicz

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Lekarski

Anti-aging properties of 4-N-furfyrylocytosine in age-differentiated eukaryotic cells, budding yeast and mouse model of ...

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Eliza Sylwia Wyszko

Instytut Chemii Bioorganicznej PAN

Modulation of mutant huntingtin level by genistein in the mouse model of Huntington's disease and its effects on psychom...

Call: PRELUDIUM 13 , Panel: NZ2

Principal investigator: Karolina Pierzynowska

Uniwersytet Gdański, Wydział Biologii

Mesenchymal stem cells as potential immunosuppression in skeletal muscle cell therapy - studies in a mouse model

Call: PRELUDIUM 12 , Panel: NZ6

Principal investigator: dr Barbara Anna Świerczek

Uniwersytet Warszawski, Wydział Biologii

Changes in protein composition and electrophysiological characteristics of glutamatergic synapse in a mouse model of acu...

Call: PRELUDIUM 10 , Panel: NZ5

Principal investigator: Mariusz Paweł Popek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The influence of a new hybryd compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide on hippocampal neuroprotect...

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Marta Andres-Mach

Instytut Medycyny Wsi im. Witolda Chodźki

The role of kidneys and haem oxygenase 1 (HO-1) in iron metabolism and haem detoxification during neonatal hyperbilirubi...

Call: PRELUDIUM 10 , Panel: NZ4

Principal investigator: Aleksandra Janina Bednarz

Uniwersytet Jagielloński, Wydział Biologii

Blastomere Biopsy and the onset of Metabolic Syndrome: a risk assessment trial in the mouse model

Call: SONATA 10 , Panel: NZ4

Principal investigator: dr Federica Zacchini

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Role of synaptic plasticity impairments in the development of asocial phenotype in mouse models of autism

Call: SONATA BIS 5 , Panel: NZ4

Principal investigator: dr Ksenia Zuzanna Meyza

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The potential influence of retinoic acid on endothelial function through change in adipocytes phenotype and adipokines p...

Call: PRELUDIUM 9 , Panel: NZ5

Principal investigator: dr Małgorzata Barbara Kalisz

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Searching for novel genes essential for human oligo- and azoospermia - mouse 'knockout' model

Call: OPUS 9 , Panel: NZ2

Principal investigator: prof. Maciej Krzysztof Kurpisz

Instytut Genetyki Człowieka PAN