Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Neuroprotective properties of biphalin in a mouse model of mild traumatic brain injury

2011/03/N/NZ4/02021

Keywords:

mild traumatic brain injury,neuroprotection,biphalin

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_9: Systems neurobiology
  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Leśniak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 175 990 PLN

Project start date (Y-m-d): 2012-09-03

Project end date (Y-m-d): 2015-09-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Tuba z pleksiglasu do unieruchamiania myszy (1 000 PLN)
  2. aparatura do wywoływania mTBI (1 488 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Biphalin protects against cognitive deficits in a mouse model of mild traumatic brain injury (mTBI).
    Authors:
    Mariusz Sacharczuk, Anna Lesniak, Chaim G. Pick, Misicka-Kesik A, Andrzej W. Lipkowski
    Academic press:
    Neuropharmacology (rok: 2016, tom: 101, strony: 506-518), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.014 - link to the publication
  2. Naloxone exacerbates memory impairments and depressive-like behavior after mild traumatic brain injury (mTBI) in mice with upregulated opioid system activity
    Authors:
    Anna Lesniak, Pawel Leszczynski, Magdalena Bujalska-Zadrozny, Chaim G. Pick, Mariusz Sacharczuk
    Academic press:
    Behavioural Brain Research (rok: 2017, tom: 30, strony: 209-216), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbr.2017.03.015 - link to the publication
  1. Neuroprotective effects of biphalin in a mouse model of mild traumatic brain injury (mTBI)
    Authors:
    Anna Lesniak, Mariusz Sacharczuk,Chaim G. Pick, Andrzej W. Lipkowski
    Conference:
    45 th meeting of the International Narcotics Research Conference (rok: 2014, ), Wydawca: brak
    Data:
    konferencja 13-18.07
    Status:
    Published
    DOI:
    link to the publication
  2. Biphalin protects against cognitive deficits in a mouse model of mild traumatic brain injury (mTBI)
    Authors:
    Anna Lesniak, Mariusz Sacharczuk, Chaim G. Pick, Andrzej W. Lipkowski
    Conference:
    20th International Symposium on Regulatory Peptides (REGPEP2014) (rok: 2014, ), Wydawca: Journal of Molecular Neuroscience
    Data:
    konferencja 7-10.09
    Status:
    Published
    DOI:
    link to the publication

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