Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of swim training on life span, oxidative energy and oxidative stress metabolism in a mouse model of amyotrophic lateral sclerosis (ALS)

2013/09/B/NZ7/02538

Keywords:

mitochondria cholesterol oxidative stress mitochondria-associated membranes (MAMs) signaling pathways

Descriptors:

  • NZ7_3: Physical culture and health promotion

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Oddziałem Pielęgniarstwa i Instytutem Medycyny Morskiej i Tropikalnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Wiesław Ziółkowski 

Number of co-investigators in the project: 7

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 1 046 100 PLN

Project start date (Y-m-d): 2014-03-21

Project end date (Y-m-d): 2017-03-20

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Ultrawirówka preparatywna (400 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Swim training modulates mouse skeletal muscle energy metabolism and ameliorates reduction in grip strength in a mouse model of amyotrophic lateral sclerosis
    Authors:
    Damian Józef Flis, Katarzyna Patrycja Dzik, Jan Jacek Kaczor, Karol Ciemiński, Małgorzata Hałoń-Gołąbek, Jędrzej Antosiewicz, Mariusz Roman Więckowski, Wiesław Ziółkowski
    Academic press:
    Int. J. Mol. Sci. (rok: 2019, tom: 20, strony: 233), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20020233 - link to the publication
  2. Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver
    Authors:
    Flis, D.J., Olek, R.A., Kaczor, J.J., Rodziewicz, E., Halon, M., Antosiewicz, J., Wozniak, M., Gabbianelli, R., Ziolkowski, W.
    Academic press:
    Oxid. Med. Cell. Longev. (rok: 2016, tom: 2016:3620929, strony: 2016:3620929), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2016/3620929 - link to the publication
  3. Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure
    Authors:
    Jedrzej Szymanski, Justyna Janikiewicz, Bernadeta Michalska, Paulina Patalas-Krawczyk, Mariasole Perrone,Wiesław Ziółkowski, Jerzy Duszynski, Paolo Pinton, Agnieszka Dobrzyn and Mariusz R. Wieckowski
    Academic press:
    Int. J. Mol. Sci. (rok: 2017, tom: 18, strony: 45315), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms18071576 - link to the publication
  4. Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice
    Authors:
    Damian Józef Flis, Katarzyna Patrycja Dzik, Jan Jacek Kaczor, Małgorzata Hałoń-Gołąbek, Jędrzej Antosiewicz, Mariusz Roman Więckowski, Wiesław Ziółkowski
    Academic press:
    Oxid. Med.Cell.Longev. (rok: 2018, tom: 2018, strony: 45303), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2018/5940748 - link to the publication

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