Projects funded by the NCN

Western diet as a potent risk factor of Alzheimer's disease progression: influence of a long-term Western diet feeding o...

Call: PRELUDIUM 15 , Panel: NZ7

Principal investigator: Angelika Więckowska-Gacek

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Role of Pon1 in Alzheimer Disease.

Call: OPUS 15 , Panel: NZ4

Principal investigator: prof. Hieronim Jakubowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Bioinżynierii

Defining the mechanism of GSK3 dependent regulation of mTOR kinase activity in neurons in physiology and pathology.

Call: PRELUDIUM 1 , Panel: NZ3

Principal investigator: Małgorzata Urbańska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Structures of oligomers of amyloid beta peptides: Multiscale molecular simulations.

Call: PRELUDIUM 14 , Panel: NZ1

Principal investigator: Dinh Quoc Huy Pham

Instytut Fizyki Polskiej Akademii Nauk

HCN channel functions in EEG synchronization and memory formation in a rat model of AD

Call: SONATA 13 , Panel: NZ4

Principal investigator: dr Paulina Kaźmierska-Grębowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: dr Agnieszka Jankowska

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Interaction of membrane-active peptides with model cell membrane and their role in a drug delivery system. Electrochemic...

Call: OPUS 12 , Panel: ST4

Principal investigator: dr Piotr Pięta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

New perspective in Alzheimer's disease therapy - multifunctional histamine H3 receptor ligands?

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Dorota Łażewska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Mechanism of substrate recognition and binding by gamma-secretase on the example of the amyloid precursor protein

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Łukasz Nierzwicki

Politechnika Gdańska, Wydział Chemiczny

Biased inverse agonists of 5-HT6 receptor and dual 5-HT6/MAO-B inhibitors - in search for new therapeutic approaches for...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Paweł Zajdel

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Synthesis and biological evaluation of novel, drug-like multifunctional ligands, as potential anti-Alzheimer's agents ta...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Dawid Panek

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Annamaria Lubelska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Barbara Malawska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Role of prion protein in amyloidogenesis and neurotoxicity of Tau protein

Call: OPUS 11 , Panel: NZ4

Principal investigator: dr hab. Krzysztof Nieznański

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Inhibitors, protein aggregation and carbon nanotube

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Mai Li

INSTYTUT FIZYKI PAN

Interactions of amyloid beta peptides with metal ions and lipid membranes: Insights from lattice and all-atom simulation...

Call: OPUS 10 , Panel: ST4

Principal investigator: prof. Mai Li

Instytut Fizyki Polskiej Akademii Nauk

Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Structure and function of Glod4 protein

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: Olga Utyro

Instytut Chemii Bioorganicznej PAN