Projects funded by the NCN

Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

Call: OPUS 10 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Estimation of antitumor activity of chemoimmunotherapy with nanoconjugates of methotrexate and vaccines based on dendrit...

Call: PRELUDIUM 10 , Panel: NZ6

Principal investigator: Agnieszka Szczygieł

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Effects of maternal high-fat or high-sugar diet on the impaired NMDA receptor composition and regulation in offspring in...

Call: SONATA 10 , Panel: NZ7

Principal investigator: dr hab. Lucyna Pomierny-Chamioło

Uniwersytet Jagielloński, Collegium Medicum, Wydział Farmaceutyczny

Search for the functionally selective 5-HT1A receptor agonists as new pharmacological tools in the development of treatm...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Marcin Kołaczkowski

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Effect of gene polymorphisms of vitamin D receptor (VDR) and the calcium receptor (CASR) in the AD.

Call: OPUS 1 , Panel: NZ7

Principal investigator: dr Łukasz Łaczmański

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski Kształcenia Podyplomowego

Molecular mechanism of interactions between GPCRs and G protein.

Call: PRELUDIUM 10 , Panel: NZ2

Principal investigator: Stefan Mordalski

Instytut Farmakologii Polskiej Akademii Nauk

Do silent synapses regulate alcohol relapse?

Call: OPUS 10 , Panel: NZ4

Principal investigator: dr hab. Katarzyna Radwańska

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

Mechanism of epigenetic-driven inactivation of tumor suppressor SIGIRR

Call: OPUS 10 , Panel: NZ6

Principal investigator: dr Katarzyna Bulek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

5-HT6 receptor ligands as addition to antipsychotic therapy in schizophrenia - an impact on body weight, metabolic param...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Anna Wesołowska

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

NMDA receptor independent, acetylcholine induced bursting activity of midbrain dopaminergic neurons - in vivo electrophy...

Call: PRELUDIUM 10 , Panel: NZ4

Principal investigator: Magdalena Walczak

Uniwersytet Jagielloński, Wydział Biologii

Endocytosis of AXL receptor and its role in AXL-mediated signaling.

Call: SONATA 10 , Panel: NZ3

Principal investigator: dr Daria Zdżalik-Bielecka

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

How estrogens and EDCs affect immune response? The role of membrane and nuclear estrogen receptors and aromatase in the ...

Call: OPUS 10 , Panel: NZ6

Principal investigator: prof. Magdalena Chadzińska

Uniwersytet Jagielloński, Wydział Biologii

Synthesis and Struktural Characterization of Small-Molecule Probes for the Programmed Death 1/ Programmed Death Ligand 1...

Call: PRELUDIUM 10 , Panel: ST5

Principal investigator: Katarzyna Guzik

Uniwersytet Jagielloński, Wydział Chemii

Molecular mechanisms of nucleic acids receptors signalling regulation by Pellino 3 protein during viral infection.

Call: SONATA BIS 5 , Panel: NZ3

Principal investigator: dr hab. Jakub Siednienko

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Interdisciplinary studies into molecular mechanisms of conformational transitions underlying GABAA receptor activation

Call: MAESTRO 7 , Panel: NZ1

Principal investigator: prof. Jerzy Mozrzymas

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

The role of Fas/FasL receptors in pathogenesis of inflammation of the nervous system induced by HSV-1 and 2 infection

Call: HARMONIA 7 , Panel: NZ6

Principal investigator: dr hab. Małgorzata Krzyżowska

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Surface carbohydrate-dependent phages select for resistant bacterial population that become more susceptible to host cle...

Call: HARMONIA 7 , Panel: NZ6

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

A virtual screening protocol based on automatically generated structure-based pharmacophore models.

Call: HARMONIA 7 , Panel: NZ2

Principal investigator: Stefan Mordalski

Instytut Farmakologii PAN

Estrogen signaling in male gonad from birth to aging. Study of the molecular mechanisms of cellular processes in mammali...

Call: SONATA BIS 5 , Panel: NZ4

Principal investigator: dr hab. Małgorzata Kotula-Balak

Uniwersytet Jagielloński, Wydział Biologii

Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Call: HARMONIA 7 , Panel: NZ7

Principal investigator: Sabina Podlewska

Instytut Farmakologii PAN

The Repository of the Polish 19th Century Translations of Shakespeare's Plays: the Resources, Translation Strategies and...

Call: OPUS 9 , Panel: HS2

Principal investigator: dr hab. Anna Cetera-Włodarczyk

Uniwersytet Warszawski, Wydział Neofilologii

Role of Pregnane-X-receptor (PXR) in the pathogenesis of primary sclerosing cholangitis (PSC)

Call: OPUS 1 , Panel: NZ5

Principal investigator: prof. Piotr Milkiewicz

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Irena Nalepa

Instytut Farmakologii PAN

Influence of autoimmune thyroid disease on the course of myasthenia gravis.

Call: OPUS 1 , Panel: NZ5

Principal investigator: dr hab. Anna Kostera-Pruszczyk

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Synthesis and binding studies of new podands based on 1,8-diaminocarbazole moiety

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: Krzysztof Bąk

Uniwersytet Warszawski, Wydział Chemii

Extracellular nucleotide gradients as regulators of glioma cell motility

Call: OPUS 9 , Panel: NZ3

Principal investigator: dr hab. Paweł Pomorski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

The expression of gene and protein of androgen receptor in testis, pituitary and adrenal gland of turkeys (Meleagris gal...

Call: PRELUDIUM 1 , Panel: NZ9

Principal investigator: Jacek Kieżun

UNIWERSYTET WARMIŃSKO-MAZURSKI W OLSZTYNIE, Wydział Biologii

Metabolic profiling of HIF stabilizers, PPAR agonists and SARMs by means of UPLC-MS/MS.

Call: PRELUDIUM 9 , Panel: ST4

Principal investigator: Katarzyna Kowalczyk

Uniwersytet Warszawski, Wydział Chemii

Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Anna Janecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Synthesis of new glutamate receptors antagonists and extensive investigation of their effect on tumor cells in the prese...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Maria Bretner

Politechnika Warszawska, Wydział Chemiczny

Coactivators and corepressors of progesterone receptors as a regulators of progesterone influence on the trissues in the...

Call: OPUS 9 , Panel: NZ4

Principal investigator: dr Robert Rękawiecki

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Crosstalk between vitamin D receptor (VDR) and retinoic acid receptors (RARs) in hematopoiesis.

Call: OPUS 9 , Panel: NZ4

Principal investigator: prof. Ewa Marcinkowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

Call: OPUS 9 , Panel: NZ4

Principal investigator: dr Magdalena Zaniewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

A Critical Edition of the Philosophical Anthology by Biernat of Lublin from MS 1717 of the Polish Academy of Sciences Li...

Call: OPUS 1 , Panel: HS2

Principal investigator: dr hab. Włodzimierz Olszaniec

Uniwersytet Warszawski, Wydział Polonistyki

Reframed Image: Reception of Prints in the Kingdom of Poland from the End of the Fifteenth to the Beginning of the Seven...

Call: OPUS 9 , Panel: HS2

Principal investigator: dr hab. Grażyna Jurkowlaniec

Uniwersytet Warszawski, Wydział Historyczny

The involvement of peroxisome proliferator-activated receptors (PPARs) in the regulation of cytokines synthesis in porci...

Call: OPUS 9 , Panel: NZ9

Principal investigator: prof. Iwona Bogacka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

The role of chemerin in the control of hypothalamic-pituitary-ovarian axis during the oestrous cycle and early pregnancy

Call: OPUS 9 , Panel: NZ9

Principal investigator: prof. Tadeusz Kamiński

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

RIG-I-like receptors and human cytomegalovirus infection in the placenta: too much of good things?

Call: PRELUDIUM 9 , Panel: NZ6

Principal investigator: Agnieszka Jabłońska

Instytut Biologii Medycznej Polskiej Akademii Nauk

Porphyromonas gingivalis protein and its homologs from other periodontopathogens - a novel group of bacterial virulence ...

Call: OPUS 9 , Panel: NZ6

Principal investigator: prof. Teresa Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig...

Call: SONATA 1 , Panel: NZ2

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN