Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

2015/19/B/NZ7/00255

Keywords:

GPR39 zinc receptor CREB BDNF NMDA neurodegeneration Alzheimer Disease.

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Młyniec 

Number of co-investigators in the project: 8

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 570 000 PLN

Project start date (Y-m-d): 2016-06-28

Project end date (Y-m-d): 2021-06-27

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Laptop.
  2. Trans Turbo Blot (aparat do transferu białek).
  3. Waga laboratoryjna (6 100 PLN)
  4. System QUANTSTUDIO REAL-TIME PCR.
  5. Wytrząsarka (2 091 PLN)
  6. Zamrażarka (40 000 PLN)
  7. Czytnik do mikropłytek i pasków z wyswietlaczem LCD i klawiaturą sterujaca oraz interfejsem do PC (50 000 PLN)
  8. Platforma to labiryntu Morris'a dla myszy i szczurów (10 000 PLN)
  9. Regał do klatek (3 szt.) (18 000 PLN)
  10. Wirówka z chłodzeniem (30 000 PLN)
  11. Aparat fotograficzny (2 999 PLN)
  12. Klatki ze stali nierdzewnej (60 szt.) (18 000 PLN)
  13. Roller laboratoryjny (2 000 PLN)
  14. Tablet.
  15. Termocykler (50 000 PLN)
  16. Komputer (2 szt.) (14 000 PLN)
  17. Termomikser (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Zinc in the Monoaminergic Theory of Depression: Its Relationship to Neural Plasticity
    Authors:
    Urszula Doboszewska, Piotr Wlaź, Gabriel Nowak, Maria Radziwoń-Zaleska, Ranji Cui, Katarzyna Młyniec
    Academic press:
    Neural Plasticity (rok: 2017, tom: 2017, strony: 3682752), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2017/3682752 - link to the publication
  2. Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the GPR39 in Dementia
    Authors:
    Michał Rychlik, Katarzyna Młyniec
    Academic press:
    Current Neuropharmacology (rok: 2020, tom: 18, strony: 45335), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1570159X17666190704153807 - link to the publication
  3. The Zinc-sensing Receptor (GPR39) Modulates Declarative Memory and Age-related Hippocampal Gene Expression in Male Mice
    Authors:
    Michal Rychlik, Gabriela Starowicz, Joanna Starnowska-Sokol, Katarzyna Mlyniec
    Academic press:
    Neuroscience (rok: 2022, tom: 503, strony: 45307), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.2174/1570159X17666190704153807 - link to the publication

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