Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Metabolic profiling of HIF stabilizers, PPAR agonists and SARMs by means of UPLC-MS/MS.

2015/17/N/ST4/03923

Keywords:

metabolic profiling HIF stabilizers PPAR agonists SARM toxicology

Descriptors:

  • NZ4_11: Metabolism
  • ST4_6: Instrumental methods in chemistry
  • ST4_3: Molecular architecture and structure

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Kowalczyk 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 148 400 PLN

Project start date (Y-m-d): 2016-02-19

Project end date (Y-m-d): 2020-02-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Blok grzewczy (2 szt.) (11 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. In vitro metabolic studies of novel selective androgen receptor modulators and their use for doping control analysis
    Authors:
    K. Kowalczyk, J.C. Torres-Elguera, A. Jarek, A. Konopka, D. Kwiatkowska, E. Bulska
    Academic press:
    Drug Testing and Analysis , Wydawca: John Wiley & Sons Ltd
    Status:
    Accepted for publication
    DOI:
    10.1002/DTA.3151 - link to the publication
  1. In vitro metabolism studies on four emerging selective androgen receptor modulators and implementation of the results into LC-MS/MS-based doping control analysis
    Authors:
    Kowalczyk K, Torres Elguera JC, Konopka A, Kwiatkowska D, Bulska E
    Conference:
    XX Euroanalysis2019 (rok: 2019, ), Wydawca: Turkish Chemical Society
    Data:
    konferencja 1-5 września 2019 r.
    Status:
    Published
  2. In vitro metabolic studies of emerging selective androgen receptor modulators (PF-0620414, TFM-4-AS-1, BMS 564929 and GSK 2881078) and implementation of the results into LC-MS/MS-based doping control analysis
    Authors:
    Kowalczyk K , Torres Elguera JC , Konopka A , Jarek A , Stanczyk D , Wicka M , Kwiatkowska D , Bulska E
    Conference:
    38th Cologne Workshop on Dope Analysis (rok: 2020, ), Wydawca: Sportverlag Strauß
    Data:
    konferencja 9-14 February 2020
    Status:
    Published

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