Projects funded by the NCN

Selective recognition of toxic heteroaromatic amines and N-nitrosamines in protein providing food products

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Włodzimierz Kutner

Instytut Chemii Fizycznej PAN

Study of SNAP-25 protein expression, NMR metabolomic analysis and behavioral characteristics in animal models of infanti...

Call: OPUS 8 , Panel: NZ4

Principal investigator: prof. Jerzy Łazarewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Transcriptomic analysis of tumor cells treated with the synergistic combination of substences activating p53 protein- se...

Call: SONATA 8 , Panel: NZ5

Principal investigator: dr Agnieszka Gdowicz-Kłosok

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Global analysis of protein expression regulated by pregnancy-associated microRNAs in the porcine endometrial cells in vi...

Call: PRELUDIUM 1 , Panel: NZ2

Principal investigator: dr Kamil Krawczyński

Instytut Rozrodu Zwierząt i Badań Żywności, Polska Akademia Nauk

Functional analysis of SLC35A transporter family - substrate specificity and ability to interact with other proteins in ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Mariusz Olczak

Uniwersytet Wrocławski, Wydział Biotechnologii

Experimental analysis of a role played by the positive selection in yeast protein evolution.

Call: OPUS 7 , Panel: NZ8

Principal investigator: dr Katarzyna Tomala

Uniwersytet Jagielloński, Wydział Biologii

Functional analysis of HSPB8 i model organisms (Danio rerio, Drosophila melanogaster): getting insights into HSPB8-linke...

Call: SONATA 7 , Panel: NZ4

Principal investigator: dr Magda Dubińska-Magiera

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Proteomic analysis of changes in brain and liver mitochondria in apoE-knockout mice – influence of metformin – an AMP-ac...

Call: PRELUDIUM 1 , Panel: NZ2

Principal investigator: dr Maciej Suski

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

Modeling realistic tear film structure including tear protein and analyzing its role in stability and biophysical proper...

Call: PRELUDIUM 6 , Panel: ST7

Principal investigator: Alicja Wizert

Politechnika Wrocławska, Wydział Podstawowych Problemów Techniki

Identification and functional analysis of genes encoding putative factors involved in chloroplast to nucleus retrograde ...

Call: OPUS 6 , Panel: NZ3

Principal investigator: prof. Stanisław Karpiński

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Ogrodnictwa, Biotechnologii i Architektury Krajobrazu

A development of a method of micro-scale synthesis of peptides labelled with stable isotopes for quantitative proteomics

Call: PRELUDIUM 6 , Panel: ST4

Principal investigator: Maciej Modzel

Uniwersytet Wrocławski, Wydział Chemii

Limb girdle muscular dystrophies (LGMD): mutations, proteins and biochemical pathways

Call: OPUS 5 , Panel: NZ4

Principal investigator: prof. Maria Rędowicz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Simulation of conformational changes related to the interdomain communication in the eukaryotic GlcN-6-P synthase by mea...

Call: PRELUDIUM 5 , Panel: NZ2

Principal investigator: Aleksandra Miszkiel

Politechnika Gdańska, Wydział Chemiczny

Structural analysis of substrate binding region of Hsp40 protein

Call: PRELUDIUM 5 , Panel: NZ2

Principal investigator: Maciej Baranowski

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Analysis of participation of two TNFSF15 protein isoforms (VEGI and TL1A) in pathomechanisms of colorectal cancer.

Call: SONATA 5 , Panel: NZ5

Principal investigator: dr Tomasz Ślebioda

Gdański Uniwersytet Medyczny, Wydział Lekarski

Virtual High Throughput Screening (vHTS) derivation of a cross-immunity model for the Influenza-A Virus Infections.

Call: OPUS 5 , Panel: NZ2

Principal investigator: dr hab. Dariusz Plewczyński

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Control system of bioprosthetic hand based on advanced analysis of biosignals and feedback from the prosthesis sensors

Call: OPUS 1 , Panel: ST6

Principal investigator: prof. Marek Kurzyński

Politechnika Wrocławska, Wydział Elektroniki

Bioinformatic analysis of GmrSD, a Type IV Modification-Dependent Restriction Systems

Call: PRELUDIUM 4 , Panel: NZ2

Principal investigator: Magdalena Machnicka

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Genetic and biological diversity of the Polish isolates of Potato virus Y infecting tomato plants and selection pressure...

Call: PRELUDIUM 4 , Panel: NZ9

Principal investigator: Julia Minicka

Instytut Ochrony Roślin - Państwowy Instytut Badawczy

Analysis of interactions of Galleria mellonella anionic and cationic defense peptides, the representatives of four disti...

Call: OPUS 3 , Panel: NZ1

Principal investigator: dr hab. Małgorzata Cytryńska

Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base...

Call: SONATA 3 , Panel: NZ5

Principal investigator: dr Paweł Domagała

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Analysis of the participation of TL1A protein and its receptor, DR3, in the pathomechanism of inflammatory bowel disease...

Call: OPUS 1 , Panel: NZ5

Principal investigator: prof. Zbigniew Kmieć

Gdański Uniwersytet Medyczny, Wydział Lekarski

Analysis of the expression profile of subunits of the TOB/SAM complex during the life cycle of the slime mold Dictyostel...

Call: PRELUDIUM 3 , Panel: NZ3

Principal investigator: Monika Mazur

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

Call: OPUS 3 , Panel: NZ3

Principal investigator: dr Agnieszka Ludwików

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Haplotypes and serum protein level of Brain-Derived Neurotrophic Factor (BDNF) analysis and their association with cogni...

Call: OPUS 1 , Panel: HS6

Principal investigator: prof. Aleksander Araszkiewicz

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera, Wydział Lekarski

Analysis of the plasma proteome in chronic kidney disease in the context of progressive cardiovascular disease.

Call: OPUS 3 , Panel: NZ2

Principal investigator: dr Magdalena Łuczak

Instytut Chemii Bioorganicznej PAN

Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Exposing unseen passages - towards identification of functional transient tunnels in protein structures

Call: PRELUDIUM BIS 5 , Panel: NZ2

Principal investigator: dr hab. Jan Brezovský

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Theoretical prediction, chemical synthesis and biological analysis of a novel class of HSPA5 inhibitors

Call: OPUS 25 , Panel: ST4

Principal investigator: prof. Arkadiusz Chworoś

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

New applications of non-conventional nonempirical methodologies for the analysis of catalytic and inhibitory properties ...

Call: OPUS 25 , Panel: ST4

Principal investigator: dr Edyta Dyguda-Kazimierowicz

Politechnika Wrocławska

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Filipek

Uniwersytet Warszawski, Wydział Chemii

Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Functional analysis of monocyte chemoattractant protein-induced protein (MCPIP) in human neuroblastoma cells

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Hanna Rokita

Uniwersytet Jagielloński Wydział Biochemii Biofizyki i Biotechnologii

Bunyaviral strategies to reorganize and exploit cellular translation

Call: SONATA BIS 12 , Panel: NZ1

Principal investigator: dr Piotr Gerlach

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Subsistence strategies and their transformations in the Late and Final Neolithic of East-Central Europe (SubTrans)

Call: OPUS 22 , Panel: HS3

Principal investigator: dr Łukasz Pospieszny

Instytut Archeologii i Etnologii Polskiej Akademii Nauk

Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

Multifaced analysis of FGF12 dimerization.

Call: PRELUDIUM 20 , Panel: NZ3

Principal investigator: Martyna Sochacka

Uniwersytet Wrocławski, Wydział Biotechnologii

Methods for the similarity analysis of low complexity regions in proteins

Call: PRELUDIUM 20 , Panel: ST6

Principal investigator: Patryk Jarnot

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Transcription factors as tools of massive operation in engineering of industrial traits in yeast

Call: OPUS 21 , Panel: NZ9

Principal investigator: dr hab. Ewelina Celińska

Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

Ancestral traits and genomic innovations in early diverging fungi - implications for mucormycosis

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr hab. Anna Muszewska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Rational engineering of E. coli penicillin G acylase for quorum quenching-based bacterial control as an effective strate...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: Bartłomiej Surpeta

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Integrative methods for modeling protein-protein complexes and multimolecular assemblies

Call: SHENG 2 , Panel: NZ2

Principal investigator: dr hab. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Self-learning systems in the design of compounds modulating GPCR receptors activation.

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Development of tools for the rational design of peptide therapeutics

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Sebastian Kmiecik

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Analysis of the molecular mechanism of phosphorylated α-synuclein and ubiquitinated protein accumulation caused by dopam...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: dr Hiroaki Taniguchi

Instytut Genetyki i Biotechnologii Zwierząt Polskiej Akademii Nauk

Why cells become smaller to survive? Analysis of tobacco BY2 cells adapted to osmotic and salt stress in the search of k...

Call: OPUS 20 , Panel: NZ9

Principal investigator: dr Agnieszka Szuba

Instytut Dendrologii Polskiej Akademii Nauk

Cooperation between the extracytoplasmic protein quality control system and the Sec translocon in the process of protein...

Call: OPUS 20 , Panel: NZ2

Principal investigator: prof. Joanna Skórko-Glonek

Uniwersytet Gdański, Wydział Biologii

Protein inference and quantification: a regularization approach

Call: PRELUDIUM 19 , Panel: ST6

Principal investigator: Mateusz Staniak

Uniwersytet Wrocławski