Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Selective recognition of toxic heteroaromatic amines and N-nitrosamines in protein providing food products

2014/15/B/NZ7/01011

Keywords:

Food toxic compound food safety toxin chemical sensing chemical sensor toxic heteroaromatic amine toxic N-nitrosoamine molecularly imprinted polymer conducting polymer thiophene polymer supramolecular complex electropolymerization molecular modeling flow-injection analysis.

Descriptors:

  • NZ7_15:
  • ST4_5:
  • ST5_4:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Włodzimierz Kutner 

Number of co-investigators in the project: 5

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 998 446 PLN

Project start date (Y-m-d): 2015-07-13

Project end date (Y-m-d): 2019-01-12

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Suszarka próżniowa (12 533 PLN)
  2. Zestaw mikroskopowy do mikroelektrodowych badań molekularnie wdrukowanych polimerów (120 000 PLN)
  3. Pompa próżniowa membranowa (8 703 PLN)
  4. Potencjostat/galwanostat z modułem pomiarów elektrochemicznej spektroskopii impedncyjnej (EIS) i niskich prądów do badań z zastosowaniem mikroelektrod oraz układ do naboru i przetwarzania danych z dedykowanym oprogramowaniem. (13 227 PLN)
  5. Komputer typu laptop (8 000 PLN)

Information in the final report

  • Publication in academic press/journals (33)
  • Book publications / chapters in book publications (3)
  1. Electrochemical determination of fumonisin B1 using a chemosensor with a recognition unit comprising molecularly imprinted polymer nanoparticles
    Authors:
    Munawar, H., Garcia-Cruz, A., Majewska, M., Karim, K., Kutner, W., and Piletsky, S. A.
    Academic press:
    Sens. Actuators, B (rok: 2020, tom: 321, strony: 128552), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2020.128552 - link to the publication
  2. Nanostructured molecularly imprinted polymers for protein chemosensing
    Authors:
    Dabrowski, M., Lach, P., Cieplak, M., Kutner, W.
    Academic press:
    Biosens. Bioelectron (rok: 2018, tom: 100, strony: 251-258), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.045 - link to the publication
  3. Gate Effect" in p‑Synephrine Electrochemical Sensing with a Molecularly Imprinted Polymer and Redox Probes
    Authors:
    Patrycja Lach, Maciej Cieplak, Marta Majewska, Krzysztof Noworyta, Piyush Sindhu Sharma, and Wlodzimierz Kutner
    Academic press:
    Analytical Chemistry (rok: 2019, tom: 91, strony: 7546-7553), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.analchem.8b05512 - link to the publication
  4. An electropolymerized molecularly imprinted polymer for selective carnosine sensing with impedimetric capacity
    Authors:
    Wojnarowicz, A., Sharma, P. S., Sosnowska, M., Lisowski, W., Huynh, T-P., D'Souza, F., Kutner, W.
    Academic press:
    J. Mater. Chem. B. (rok: 2016, tom: 4, strony: 1156-1165), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c5tb02260f - link to the publication
  5. Molecularly imprinted polymers for separating and sensing of macromolecular compounds and microorganisms
    Authors:
    Iskierko, Z., Sharma, P. S., Bartold, K., Pietrzyk-Le, A., Noworyta, K., Kutner, W.
    Academic press:
    Biotechnol. Adv. (rok: 2016, tom: 34, strony: 30-46), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biotechadv.2015.12.002 - link to the publication
  6. Electrochemical determination of fumonisin B1 using a chemosensor with a recognition unit comprising molecularly imprinted polymer nanoparticles
    Authors:
    Munawar, H., Garcia-Cruz, A., Majewska, M., Karim, K., Kutner, W., and Piletsky, S. A.
    Academic press:
    Sens. Actuators, B (rok: 2020, tom: 321, strony: 128552), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2020.128552 - link to the publication
  7. Synthesis and application of a "plastic antibody" in electrochemical microfluidic platform for oxytocin determination
    Authors:
    Sharma, P. S., Iskierko, Z., Noworyta, K., Cieplak, M., Borowicz, P., Lisowski, W., D'Souza F., and Kutner, W.
    Academic press:
    Biosens. Bioelectron. (rok: 2018, tom: 100, strony: 251-258), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2017.09.009 - link to the publication
  8. Promoting bioanalytical concepts in genetics: A TATA box molecularly imprinted polymer as a small isolated fragment of the DNA damage repairing system
    Authors:
    Bartold, K., Pietrzyk-Le, A., Lisowski, W., Golebiewska, K., Siklitskaya, A., Borowicz, P., Shao, S., D'Souza, F., and Kutner, W.
    Academic press:
    Mater. Sci. Eng., C (rok: 2019, tom: 100, strony: 45667), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.02.038 - link to the publication
  9. Potentiometric chemosensor for neopterin, a cancer biomarker, using an electrochemically synthesized molecularly imprinted polymer as the recognition unit
    Authors:
    Sharma, P. S., Wojnarowicz, A., Sosnowska, M., Benincori, T., Noworyta, K., D'Souza, F., Kutner, W.
    Academic press:
    Biosens. Bioelectron. (rok: 2016, tom: 77, strony: 565-572), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.013 - link to the publication
  10. Direct determination of small RNAs using a biotinylated polythiophene modified impedimetric genosensor
    Authors:
    Voccia, D., Sosnowska M., Bettazzi, F., Roscigno, G., Condorelli, G., Fratini, E., De Franciscis, V., Chitta, R., D'Souza, F., Kutner, W., Palchetti, I.
    Academic press:
    J. Mater. Chem. C (rok: 2017, tom: 5, strony: 969-977), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6tc03812c - link to the publication
  11. Molecularly Imprinted Polymer Chemosensor for Selective Determination of an N-Nitroso-L-proline Food Toxin
    Authors:
    Patrycja Lach, Piyush Sindhu Sharma, Karolina Golebiewska, Maciej Cieplak, Francis D'Souza, Wlodzimierz Kutner
    Academic press:
    Chemistry - A European Journal (rok: 2017, tom: 23, strony: 1942 – 1949), Wydawca: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/chem.201604799 - link to the publication
  12. Molecularly Imprinted Polymer Chemosensor for Selective Determination of an N-Nitroso-L-proline Food Toxin
    Authors:
    Patrycja Lach, Piyush Sindhu Sharma, Karolina Golebiewska, Maciej Cieplak, Francis D'Souza, Wlodzimierz Kutner
    Academic press:
    Chemistry - A European Journal (rok: 2017, tom: 23, strony: 1942 – 1949), Wydawca: Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/chem.201604799 - link to the publication
  13. Programmed transfer of sequence information into molecularly imprinted polymer (MIP) for hexa(2,2'-bithien-5-yl) DNA analog formation towards single nucleotide polymorphism (SNP) detection
    Authors:
    Bartold, K., Pietrzyk-Le, A., Huynh T.-P., Iskierko, Z., Sosnowska, M., Noworyta, K., Lisowski, W., Sannicolò, F., Mussini, P. R., Cauteruccio, S., Licandro, E., D'Souza, F., and Kutner, W.
    Academic press:
    ACS Appl. Mater. Interfaces (rok: 2017, tom: 9, strony: 3948-3958), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acsami.6b14340 - link to the publication
  14. Artificial Biosensors: How Can Molecular Imprinting Mimic Biorecognition?
    Authors:
    Maciej Cieplak, Włodzimierz Kutner
    Academic press:
    Trends in Biotechnology (rok: 2016, tom: 34, strony: 922-941), Wydawca: A Cell Press
    Status:
    Published
    DOI:
    10.1016/j.tibtech.2016.05.011 - link to the publication
  15. Electrochemical sensor for selective tyramine determination, amplified by a molecularly imprinted polymer film
    Authors:
    Viknasvarri Ayerdurai, Maciej Cieplak, Krzysztof R. Noworyta, Marianna Gajda, Agnieszka Ziminska, Marta Sosnowska, Joanna Piechowska, Pawel Borowicz, Wojciech Lisowski, Shuai Shao, Francis D'Souza, Wlodzimierz Kutner
    Academic press:
    Electrochemical sensor for selective tyramine determination, amplified by a molecularly imprinted polymer film (rok: 2021, tom: 138, strony: 107695), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2020.107695 - link to the publication
  16. Molecularly imprinted polymers for separating and sensing of macromolecular compounds and microorganisms
    Authors:
    Iskierko, Z., Sharma, P. S., Bartold, K., Pietrzyk-Le, A., Noworyta, K., Kutner, W.
    Academic press:
    Biotechnol. Adv. (rok: 2016, tom: 34, strony: 30-46), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biotechadv.2015.12.002 - link to the publication
  17. Promoting bioanalytical concepts in genetics: A TATA box molecularly imprinted polymer as a small isolated fragment of the DNA damage repairing system
    Authors:
    Bartold, K., Pietrzyk-Le, A., Lisowski, W., Golebiewska, K., Siklitskaya, A., Borowicz, P., Shao, S., D'Souza, F., and Kutner, W.
    Academic press:
    Mater. Sci. Eng., C (rok: 2019, tom: 100, strony: 45667), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.02.038 - link to the publication
  18. Synthesis and application of a "plastic antibody" in electrochemical microfluidic platform for oxytocin determination
    Authors:
    Sharma, P. S., Iskierko, Z., Noworyta, K., Cieplak, M., Borowicz, P., Lisowski, W., D'Souza F., and Kutner, W.
    Academic press:
    Biosens. Bioelectron. (rok: 2018, tom: 100, strony: 251-258), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2017.09.009 - link to the publication
  19. Direct determination of small RNAs using a biotinylated polythiophene modified impedimetric genosensor
    Authors:
    Voccia, D., Sosnowska M., Bettazzi, F., Roscigno, G., Condorelli, G., Fratini, E., De Franciscis, V., Chitta, R., D'Souza, F., Kutner, W., Palchetti, I.
    Academic press:
    J. Mater. Chem. C (rok: 2017, tom: 5, strony: 969-977), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6tc03812c - link to the publication
  20. Gate effect" in molecularly imprinted polymers: the current state of understanding
    Authors:
    Piyush Sindhu Sharma, Alvaro Garcia-Cruz, Maciej Cieplak, Krzysztof Noworyta, and Wlodzimierz Kutner
    Academic press:
    Current Opinion in Electrochemistry (rok: 2019, tom: 16, strony: 50-56), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.coelec.2019.04.020 - link to the publication
  21. Chemosensor for selective determination of 2,4,6-trinitrophenol using a custom designed imprinted polymer recognition unit cross-linked to a fluorophore transducer
    Authors:
    Huynh, T.-P., Wojnarowicz, A., Majka, A., Woznicki, P., Borowicz, P., D'Souza, F., and Kutner, W.
    Academic press:
    ACS Sensors (rok: 2016, tom: 1, strony: 636-639), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acssensors.6b00055 - link to the publication
  22. Molecularly imprinted polymer based extended-gate field-effect transistor chemosensor for phenylalanine enantioselective sensing
    Authors:
    Iskierko, Z., Checinska, A., Sharma, P. S., Golebiewska, K., Noworyta, K., Borowicz, P., Fronc, K., Bandi, V, D'Souza, F., and Kutner, W.
    Academic press:
    J. Mater. Chem. C (rok: 2017, tom: 5, strony: 969-977), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6tc03812c - link to the publication
  23. Programmed transfer of sequence information into molecularly imprinted polymer (MIP) for hexa(2,2'-bithien-5-yl) DNA analog formation towards single nucleotide polymorphism (SNP) detection
    Authors:
    Bartold, K., Pietrzyk-Le, A., Huynh T.-P., Iskierko, Z., Sosnowska, M., Noworyta, K., Lisowski, W., Sannicolò, F., Mussini, P. R., Cauteruccio, S., Licandro, E., D'Souza, F., and Kutner, W.
    Academic press:
    ACS Appl. Mater. Interfaces (rok: 2017, tom: 9, strony: 3948-3958), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acsami.6b14340 - link to the publication
  24. Early diagnosis of fungal infections using piezomicrogravimetric and electric chemosensors based on polymers molecularly imprinted with D-arabitol
    Authors:
    Dabrowski, M., Sharma, P. S., Iskierko, Z., Noworyta, K., Cieplak, M., Lisowski, W., Oborska, S., Kuhn, A., and Kutner, W.
    Academic press:
    Biosens. Bioelectron. (rok: 2016, tom: 79, strony: 627–635), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2015.12.088 - link to the publication
  25. Oligonucleotide Determination via Peptide Nucleic Acid Macromolecular Imprinting in an Electropolymerized CG-Rich Artificial Oligomer Analogue
    Authors:
    Katarzyna Bartold, Agnieszka Pietrzyk-Le, Karolina Golebiewska, Wojciech Lisowski, Silvia Cauteruccio, Emanuela Licandro, Francis D'Souza, and Wlodzimierz Kutner
    Academic press:
    ACS Applied Materials & Interfaces (rok: 2018, tom: 10, strony: 27562−27569), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acsami.8b09296 - link to the publication
  26. Oligonucleotide Determination via Peptide Nucleic Acid Macromolecular Imprinting in an Electropolymerized CG-Rich Artificial Oligomer Analogue
    Authors:
    Katarzyna Bartold, Agnieszka Pietrzyk-Le, Karolina Golebiewska, Wojciech Lisowski, Silvia Cauteruccio, Emanuela Licandro, Francis D'Souza, and Wlodzimierz Kutner
    Academic press:
    ACS Applied Materials & Interfaces (rok: 2018, tom: 10, strony: 27562−27569), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acsami.8b09296 - link to the publication
  27. Electrochemical sensor for selective tyramine determination, amplified by a molecularly imprinted polymer film
    Authors:
    Viknasvarri Ayerdurai, Maciej Cieplak, Krzysztof R. Noworyta, Marianna Gajda, Agnieszka Ziminska, Marta Sosnowska, Joanna Piechowska, Pawel Borowicz, Wojciech Lisowski, Shuai Shao, Francis D'Souza, Wlodzimierz Kutner
    Academic press:
    Electrochemical sensor for selective tyramine determination, amplified by a molecularly imprinted polymer film (rok: 2021, tom: 138, strony: 107695), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2020.107695 - link to the publication
  28. Potentiometric chemosensor for neopterin, a cancer biomarker, using an electrochemically synthesized molecularly imprinted polymer as the recognition unit
    Authors:
    Sharma, P. S., Wojnarowicz, A., Sosnowska, M., Benincori, T., Noworyta, K., D'Souza, F., Kutner, W.
    Academic press:
    Biosens. Bioelectron. (rok: 2016, tom: 77, strony: 565-572), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.013 - link to the publication
  29. Gate Effect" in p‑Synephrine Electrochemical Sensing with a Molecularly Imprinted Polymer and Redox Probes
    Authors:
    Patrycja Lach, Maciej Cieplak, Marta Majewska, Krzysztof Noworyta, Piyush Sindhu Sharma, and Wlodzimierz Kutner
    Academic press:
    Analytical Chemistry (rok: 2019, tom: 91, strony: 7546-7553), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.analchem.8b05512 - link to the publication
  30. Molecularly imprinted polymer based extended-gate field-effect transistor chemosensor for phenylalanine enantioselective sensing
    Authors:
    Iskierko, Z., Checinska, A., Sharma, P. S., Golebiewska, K., Noworyta, K., Borowicz, P., Fronc, K., Bandi, V, D'Souza, F., and Kutner, W.
    Academic press:
    J. Mater. Chem. C (rok: 2017, tom: 5, strony: 969-977), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c6tc03812c - link to the publication
  31. Gate effect" in molecularly imprinted polymers: the current state of understanding
    Authors:
    Piyush Sindhu Sharma, Alvaro Garcia-Cruz, Maciej Cieplak, Krzysztof Noworyta, and Wlodzimierz Kutner
    Academic press:
    Current Opinion in Electrochemistry (rok: 2019, tom: 16, strony: 50-56), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.coelec.2019.04.020 - link to the publication
  32. An electropolymerized molecularly imprinted polymer for selective carnosine sensing with impedimetric capacity
    Authors:
    Wojnarowicz, A., Sharma, P. S., Sosnowska, M., Lisowski, W., Huynh, T-P., D'Souza, F., Kutner, W.
    Academic press:
    J. Mater. Chem. B. (rok: 2016, tom: 4, strony: 1156-1165), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c5tb02260f - link to the publication
  33. Chemosensor for selective determination of 2,4,6-trinitrophenol using a custom designed imprinted polymer recognition unit cross-linked to a fluorophore transducer
    Authors:
    Huynh, T.-P., Wojnarowicz, A., Majka, A., Woznicki, P., Borowicz, P., D'Souza, F., and Kutner, W.
    Academic press:
    ACS Sensors (rok: 2016, tom: 1, strony: 636-639), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acssensors.6b00055 - link to the publication
  1. Macromolecular imprinting for improved health security
    Authors:
    Sharma, P. S., Iskierko, Z., D'Souza, F., Kutner W.
    Book:
    Biosensors for Security and Bioterrorism Applications (rok: 2016, tom: -, strony: 141-160), Wydawca: Springer International Publishing AG
    Status:
    Published
    DOI:
    link to the publication
  2. Protein Determination Using Molecularly Imprinted Polymer (MIP) Chemosensors
    Authors:
    Maciej Cieplak, Włodzimierz Kutner
    Book:
    Polymer Chemistry Series No. 28 Molecularly Imprinted Polymers for Analytical Chemistry Applications (rok: 2018, tom: 28, strony: 282-329), Wydawca: The Royal Society of Chemistry
    Status:
    Published
  3. Macromolecular imprinting for improved health security
    Authors:
    Sharma, P. S., Iskierko, Z., D'Souza, F., Kutner W.
    Book:
    Biosensors for Security and Bioterrorism Applications (rok: 2016, tom: -, strony: 141-160), Wydawca: Springer International Publishing AG
    Status:
    Published
    DOI:
    link to the publication

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