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DEVELOPMENT AND ANALYSIS OF SMALL COMPOUNDS AS CANDIDATE INHIBITORS OF PLANT GROUP A PROTEIN PHOSPHATASES TYPE 2C

2016/22/E/NZ3/00345

Keywords:

protein phosphatases type 2C small chemical compounds protein phosphatase type 2C inhibitors crystalography

Descriptors:

  • NZ3_7: Signal transduction
  • ST4_4: Theoretical and computational chemistry
  • NZ1_9: Biotechnology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Ludwików 

Number of co-investigators in the project: 6

Call: SONATA BIS 6 - announced on 2016-06-15

Amount awarded: 2 108 000 PLN

Project start date (Y-m-d): 2017-04-26

Project end date (Y-m-d): 2024-04-25

Project duration:: 60 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (4)
  1. Identification of Novel miRNAs and Their Target Genes in the Response to Abscisic Acid in Arabidopsis
    Authors:
    Syed Muhammad Muntazir Mehdi, Sivakumar Krishnamoorthy, Michal Wojciech Szczesniak, Agnieszka Ludwików
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 7153), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/ijms22137153 - link to the publication
  2. Identification of novel inhibitors of a plant group A protein phosphatase type 2C using a combined in silico and biochemical approach
    Authors:
    Maciej Janicki, Małgorzata Marczak, Agata Cieśla and Agnieszka Ludwików*
    Academic press:
    Frontiers in Plant Science (rok: 2020, tom: 11, strony: 526460), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fpls.2020.526460 - link to the publication
  1. Macrocycles as protein-protein interactions specific potential inhibitors for Arabidopsis group A protein phosphatases type 2C
    Authors:
    Syed Muhammad Muntazir Mehdi
    Conference:
    2nd World Congress and Expo on Biotechnology and Bioengineering (rok: 2018, ), Wydawca: BioCore
    Data:
    konferencja June 25-27, 2018, Dubai, UAE
    Status:
    Published
  2. Virtual screening and bioassay of specific potential inhibitors for Arabidopsis group A protein phosphatases type 2 C
    Authors:
    Janicki M., Ludwików A
    Conference:
    Botaniktagung 2017 (rok: 2017, ), Wydawca: Kiel University
    Data:
    konferencja 17-21.09.2017
    Status:
    Published
  3. SMALL OLIGOPEPTIDES AS SPECIFIC POTENTIAL INHIBITORS FOR ARABIDOPSIS GROUP A PROTEIN PHOSPHATASES TYPE 2C
    Authors:
    Maciej Janicki, Sivakumar Krishnamoorthy, Agnieszka Ludwików
    Conference:
    Proceedings of Researchfora International Conference (rok: 2018, ), Wydawca: IRAJ
    Data:
    konferencja Chennai, India, 23rd--24th August 2018
    Status:
    Published
  4. Virtual screening and bioassay of specific potential inhibitors for Arabidopsis group A protein phosphatases type 2C
    Authors:
    Maciej Janicki, Małgorzata Marczak and Agnieszka Ludwików
    Conference:
    18th European Congress On Biotechnology (rok: 2018, ), Wydawca: Elsevier
    Data:
    konferencja 1 - 4 July 2018, Geneva, Switzerland
    Status:
    Published

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