Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Transcription factors as tools of massive operation in engineering of industrial traits in yeast

2021/41/B/NZ9/00086

Keywords:

transcription factors (sing. TF pl. TFs) heterologous protein production environmental stresses stress factors systematic functional analysis Yarrowia lipolytica yeast high-throughput techniques modular cloning Golden Gate genome editing CRISPR-Cas9

Descriptors:

  • NZ9_13: Other related subjects
  • NZ1_9: Biotechnology

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewelina Celińska 

Number of co-investigators in the project: 3

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 1 374 000 PLN

Project start date (Y-m-d): 2021-12-27

Project end date (Y-m-d): 2025-12-26

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. "Fight-flight-or-freeze" - how Yarrowia lipolytica responds to stress at molecular level?
    Authors:
    Celińska Ewelina
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2022, tom: 106, strony: 3369–3395), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-022-11934-x - link to the publication
  2. Molecular background of HAC1-driven improvement in the secretion of recombinant protein in Yarrowia lipolytica based on comparative transcriptomics
    Authors:
    Paulina Korpys-Woźniak, Ewelina Celińska⁎
    Academic press:
    Biotechnology Reports (rok: 2023, tom: 38, strony: e00801), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.btre.2023.e00801 - link to the publication
  3. Transcription factors enhancing synthesis of recombinant proteins and resistance to stress in Yarrowia lipolytica
    Authors:
    Maria Gorczyca, Jean‑Marc Nicaud, Ewelina Celińska*
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2023, tom: 107, strony: 4853–4871), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-023-12607-z - link to the publication
  4. "Fight-flight-or-freeze" - how Yarrowia lipolytica responds to stress at molecular level?
    Authors:
    Celińska Ewelina
    Academic press:
    Applied Microbiology and Biotechnology (rok: 2022, tom: 106, strony: 3369–3395), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00253-022-11934-x - link to the publication

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