Projects funded by the NCN

Information on the principal investigator and host institution

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Solving the elaborated architecture of the D. radiodurans S-layer: structural analysis of its type IV-like piliation system

2018/30/M/NZ1/00284

Keywords:

Deinococcus radiodurans S-layer type IV-like piliation system single particle analysis membrane protein

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_2: Biochemistry
  • NZ1_3: Biophysics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Dario Piano 

Number of co-investigators in the project: 4

Call: HARMONIA 10 - announced on 2018-06-15

Amount awarded: 281 400 PLN

Project start date (Y-m-d): 2019-05-16

Project end date (Y-m-d): 2020-11-15

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Structural analysis of the architecture and in situ localization of the main S-layer complex in Deinococcus radiodurans
    Authors:
    Domenica Farci; Sami Kereïche; Sushil Pangeni; Patrycja Haniewicz; Igor V Bodrenko; Matteo Ceccarelli; Mathias Winterhalter; Dario Piano
    Academic press:
    Structure (rok: 2021, tom: 29, strony: 45298), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.str.2021.06.014 - link to the publication
  2. Structural insights into the main S-layer unit of Deinococcus radiodurans reveal a massive protein complex with porin-like features
    Authors:
    Domenica Farci, Mehmet Alphan Aksoyoglu, Stefano Francesco Farci, Jayesh Arun Bafna, Igor Bodrenko, Matteo Ceccarelli, Joanna Kirkpatrick, Mathias Winterhalter, Sami Kereïche, Dario Piano
    Academic press:
    Journal of Biological Chemistry (rok: 2020, tom: 295, strony: 4224-4236), Wydawca: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1074/jbc.RA119.012174 - link to the publication
  3. The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions.
    Authors:
    Domenica Farci, Patrycja Haniewicz, Daniele de Sanctis, Luca Iesu, Sami Kereïche, Mathias Winterhalter, Dario Piano.
    Academic press:
    Journal of Biological Chemistry (rok: 2022, tom: 298, strony: 45299), Wydawca: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1016/j.jbc.2022.102031 - link to the publication

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