Projects funded by the NCN

Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

Call: PRELUDIUM 12 , Panel: NZ5

Principal investigator: Justyna Józefa Brodowicz

Instytut Farmakologii PAN

The search for epigenetic differences in patterns of response to environmental stress in isolated and open populations o...

Call: PRELUDIUM 12 , Panel: NZ8

Principal investigator: Przemysław Piotr Tomczyk

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

Call: OPUS 12 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Executive functions training as a moderator of outcome of gestalt psychotherapy for depressive persons: a randomized con...

Call: PRELUDIUM 12 , Panel: HS6

Principal investigator: Jarosław Wasielewski

Szkoła Wyższa Psychologii Społecznej w Warszawie, Wydział Psychologii

Molecular characteristics of stress-resilient phenotype using mice models.

Call: OPUS 12 , Panel: NZ4

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii PAN

Patophysiology of depression: molecular regulation of melatonin homeostasis

Call: OPUS 12 , Panel: NZ5

Principal investigator: dr hab. Monika Paulina Dmitrzak-Węglarz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like beha...

Call: PRELUDIUM 12 , Panel: NZ4

Principal investigator: dr Patrycja Anna Pańczyszyn-Trzewik

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

The role of halogen bonding in interaction of ligands with SERT.

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Jakub Staroń

Instytut Farmakologii PAN

Modulation of amygdala neural network activity by the 5-HT7 receptor

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Krzysztof Tokarski

Instytut Farmakologii PAN

Effect of modulation of the GPR39 zinc receptor on glutamatergic and gabaergic transmission in the context of antidepres...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Gabriela Joanna Starowicz

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

The importance of interaction between NMDA and AMPA receptors and scaffolding proteins in the excitatory synaptic in the...

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr hab. Magdalena Jolanta Sowa-Kućma

Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

Effect of co-treatment with fluoxetine and zinc in a chronic restraint stress (CRS) animal model of depression

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Paulina Misztak

Uniwersytet Jagielloński- Collegium Medicum

The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Annamaria Teresa Lubelska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Synthesis and pharmacological characterization of structurally diverse chemical analogues of compound PO-10 as multiple ...

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Zagórska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Molecular mechanisms of lithium action in depression and mania: animal model and clinical study in bipolar disorder

Call: OPUS 11 , Panel: NZ5

Principal investigator: prof. Joanna Wiktoria Twarowska-Hauser

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal...

Call: PRELUDIUM 11 , Panel: NZ4

Principal investigator: Joanna Ewa Sowa

Instytut Farmakologii PAN

The effect of gratitude on psychological well-being and affect of women with breast cancer and women with depression.

Call: PRELUDIUM 11 , Panel: HS6

Principal investigator: Joanna Tomczyk

Szkoła Wyższa Psychologii Społecznej w Warszawie, Wydział Psychologii

The role of selected signaling pathways in zinc deficiency

Call: OPUS 10 , Panel: NZ4

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

Call: PRELUDIUM 9 , Panel: NZ4

Principal investigator: Dariusz Marek Żurawek

Instytut Farmakologii PAN

Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Magnetic Resonance Spectroscopy Evaluation of Brain Metabolites Following Microbiotic Diet

Call: OPUS 9 , Panel: NZ4

Principal investigator: prof. Grzegorz Jan Stanisz

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

Call: OPUS 9 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii PAN

Fundamental understanding of melting point depression in nanomultilayer systems

Call: OPUS 9 , Panel: ST8

Principal investigator: prof. Małgorzata Anna Lewandowska

Politechnika Warszawska, Wydział Inżynierii Materiałowej

Neurocognitive dysfunction in chronic hepatitis C: Effect of extrahepatic replication and immune activation

Call: OPUS 8 , Panel: NZ6

Principal investigator: prof. Tomasz Laskus

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Relationship between inbreeding and fitness in dioecious plants: the case study of Taxus baccata

Call: OPUS 8 , Panel: NZ9

Principal investigator: dr hab. Igor Chybicki

Uniwersytet Kazimierza Wielkiego, Wydział Nauk Przyrodniczych

Synthesis and pharmacological evaluation of novel benzizoxazolepropylpyrolidine derivatives as multifunctional ligands w...

Call: SONATA 8 , Panel: NZ7

Principal investigator: dr Monika Emilia Marcinkowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Is it worth turning depressed mood into the joke? The effect of humor on emotion regulation in vulnerability to depressi...

Call: SONATA 8 , Panel: HS6

Principal investigator: dr Anna Magdalena Braniecka

Szkoła Wyższa Psychologii Społecznej w Warszawie, Wydział Psychologii

The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

Call: OPUS 7 , Panel: NZ7

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii PAN

Pessimism as cognitive biomarker of depression in animal model

Call: OPUS 7 , Panel: NZ4

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Mitochondrial DNA damage and repair in depression

Call: PRELUDIUM 7 , Panel: NZ7

Principal investigator: Piotr Lech Czarny

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

Call: SONATA 7 , Panel: NZ7

Principal investigator: dr Katarzyna Małgorzata Stachowicz

Instytut Farmakologii PAN

Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

Call: OPUS 7 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

A longitudinal study of relationship status and the mental and physical health of young adults in Poland and in the Unit...

Call: OPUS 7 , Panel: HS6

Principal investigator: dr Katarzyna Adamczyk

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Nauk Społecznych

Improved method of memory bias measurement and training

Call: SONATA 5 , Panel: HS6

Principal investigator: dr Borysław Witold Paulewicz

Szkoła Wyższa Psychologii Społecznej w Warszawie, Wydział Zamiejscowy w Katowicach

Synthesis and biological evaluation of pyrrolidine-2,5-dione derivatives as potential antidepressant agents.

Call: OPUS 5 , Panel: NZ7

Principal investigator: dr Andrzej Józef Chodkowski

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

Call: OPUS 5 , Panel: NZ7

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

Call: SONATA 5 , Panel: NZ7

Principal investigator: dr Magdalena Jolanta Sowa-Kućma

Instytut Farmakologii PAN

Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

Call: HARMONIA 4 , Panel: NZ7

Principal investigator: dr Bernadeta Szewczyk

Instytut Farmakologii PAN

The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

Call: PRELUDIUM 4 , Panel: NZ7

Principal investigator: Jan Stanisław Detka

Instytut Farmakologii PAN

Genes encoding for iodothyronine deiodinase, mRNA and protein levels in the complex mechanisms of the risk of recurrent ...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr Elżbieta Gałecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Molecular markers of stress resilience in animal model of depression

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Marta Dziedzicka-Wasylewska

Instytut Farmakologii PAN

Origin and evolution of closed depression of the loess area of the Lublin Uppland and their importance in reconstruction...

Call: OPUS 4 , Panel: ST10

Principal investigator: dr Renata Agnieszka Kołodyńska-Gawrysiak

Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Nauk o Ziemi i Gospodarki Przestrzennej

On the mechanism of NMDA receptor changes in the treatment of depression.

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Maria Teresa Radziwoń-Zaleska

Warszawski Uniwersytet Medyczny, Wydział Lekarski

The role of dominant controlling functions over stimulation in cognitive performance in anxiety and depression.

Call: SONATA BIS 2 , Panel: HS6

Principal investigator: dr hab. Małgorzata Fajkowska

Instytut Psychologii PAN

Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d...

Call: OPUS 3 , Panel: NZ7

Principal investigator: prof. Małgorzata Maria Filip

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Evaluation of the role of subpopulations of T lymphocytes (Treg: CD4+CD25+, CD4+CD25- i Teff: Th2) in depression using p...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr Sylwia Kędracka-Krok

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Evaluation of pharmacological activity of new, nonselective gamma-aminobutyric acid (GABA) transport inhibitors in some ...

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr hab. Kinga Sałat

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny