Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

35 projects found matching your search criteria :

  1. New nucleotide analogs containing triazole within oligophosphate bridge as mimics of the 5' end of mRNA - synthesis, pro...

    Call: PRELUDIUM 9 , Panel: ST5

    Principal investigator: Sylwia Ciechanowicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  2. Chemical syntesis and evaluation of biochemical properties of 7-methyloguanosine 5'-diphosphate analogs as inhibitors of...

    Call: PRELUDIUM 1 , Panel: NZ1

    Principal investigator: Marcin Ziemniak

    Uniwersytet Warszawski, Wydział Fizyki

  3. Studies on the synthesis of newly discovered cyclic N6-threonylcarbamoyladenosine (ct6A) and its analogues and on the in...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: Michał Matuszewski

    Politechnika Łódzka, Wydział Chemiczny

  4. Biosynthesis of seleno-modified nucleosides in the anticodon loop of transfer ribonucleic acids. Evaluation of the enzym...

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Barbara Nawrot

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  5. Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

    Call: OPUS 6 , Panel: ST5

    Principal investigator: dr hab. Marzena Jankowska-Anyszka

    Uniwersytet Warszawski, Wydział Chemii

  6. Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

    Call: SONATA BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  7. New methods for mRNA 5' end labeling and examples of their application in studies on RNA metabolism and searching for in...

    Call: OPUS 5 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  8. Transformation of 5'-O-monothiophosphate nucleoside to 5'-O-monophosphate in the cell - possible metabolism of phosphoro...

    Call: OPUS 5 , Panel: ST5

    Principal investigator: dr Agnieszka Krakowiak

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  9. Synthesis and study of spectroscopic and bilogical properties of nucleosides modyfied by new stilbene derivatives

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Przemysław Szczeciński

    Politechnika Warszawska, Wydział Chemiczny

  10. Pronucloetides - a pathway to cellular DNA sensitization to ionizing radiation

    Call: PRELUDIUM 4 , Panel: ST5

    Principal investigator: Magdalena Zdrowowicz

    Uniwersytet Gdański, Wydział Chemii

  11. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Marcin Chmielewski

    Instytut Chemii Bioorganicznej PAN

  12. New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological ac...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  13. Influence of nucleotide sequence on the yield of radio- and photodamage to double stranded DNA fragments labelled with t...

    Call: OPUS 3 , Panel: ST5

    Principal investigator: prof. Janusz Rak

    Uniwersytet Gdański, Wydział Chemii

  14. Adenosine 5'-phosphoramidate as a novel signaling molecule; Study of enzymatic synthesis of this nucleotide and analysis...

    Call: OPUS 3 , Panel: NZ1

    Principal investigator: prof. Andrzej Guranowski

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa i Bioinżynierii

  15. New reagents and methods in synthesis of modified nucleotides and their application for preparation biochemical tools an...

    Call: SONATA BIS 1 , Panel: ST5

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  16. Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

    Call: SONATA 1 , Panel: ST5

    Principal investigator: dr Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  17. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Guga

    Centrum Badań Molekularnych i Makromolekularnych PAN

  18. Feel the chemistry if you're close enough - proximity-induced SuFEx ligation for mRNA biology and medicine

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  19. Modified (oligo)nucleotides for photo-controlled manipulation of mRNA

    Call: SONATA 18 , Panel: ST4

    Principal investigator: dr Marcin Warmiński

    Uniwersytet Warszawski, Wydział Fizyki

  20. Synthesis and structural/biophysical studies of model mRNA/mt-tRNA oligomers to evaluate the role of modified nucleoside...

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr hab. Grażyna Leszczyńska

    Politechnika Łódzka

  21. mRNA 5' end methylation status: towards deeper understanding of biological role and identification of synthetic mimics

    Call: OPUS 17 , Panel: ST4

    Principal investigator: dr hab. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  22. Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: dr Justyna Gołębiewska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  23. Synthesis and characterization of new molecular probes for monitoring activity of enzymes associated with RNA decapping ...

    Call: OPUS 16 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  24. Why Nature introduced selenium to wobble nucleosides in transfer RNA?

    Call: OPUS 15 , Panel: ST5

    Principal investigator: prof. Barbara Nawrot

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  25. Functional glycol nucleic acid (fun-GNA) nucleosides, nucleotides and oligos: synthesis and properties

    Call: OPUS 15 , Panel: ST5

    Principal investigator: prof. Konrad Kowalski

    Uniwersytet Łódzki, Wydział Chemii

  26. The role of extracellular ATP fraction in induction of epithelial-mesenchymal transition - studies using analogs of nucl...

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Róża Pawłowska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  27. Synthesis of trimethyl cap analogs modified with molecular rotors and their application in nuclear transport studies

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Błażej Wojtczak

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  28. Synthesis and structural studies of oligonucleotides with tRNA anticodon stem-loop sequences containing newly discovered...

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Elżbieta Sochacka

    Politechnika Łódzka, Wydział Chemiczny

  29. N-Oxide phosphobetaines in new synthetic strategies for P-modified phosphates and polyphospates of natural biomolecules ...

    Call: PRELUDIUM 12 , Panel: ST5

    Principal investigator: Magdalena Materna

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  30. Chemically modified mRNA for studies on cellular processes and therapeutic applications

    Call: OPUS 11 , Panel: ST5

    Principal investigator: prof. Jacek Jemielity

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  31. Fluorescent biosensors based on quantum dots and purines/pyrimidines - synthesis, characterization and potential applica...

    Call: PRELUDIUM 11 , Panel: ST5

    Principal investigator: Łucja Rodzik-Czałka

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  32. Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

    Call: SONATA 11 , Panel: ST5

    Principal investigator: dr Karolina Piecyk

    Uniwersytet Warszawski, Wydział Chemii

  33. Aryl nucleoside phosphoroamidates - a new generation of anti-HIV pronucleotides.

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Jacek Stawiński

    Instytut Chemii Bioorganicznej PAN

  34. Purine salvage pathway enzymes as a target for pathogenic organisma lacking de novo purine synthesis -cas study of Helic...

    Call: HARMONIA 7 , Panel: NZ1

    Principal investigator: prof. Maria Bzowska

    Uniwersytet Warszawski, Wydział Fizyki

  35. Synthesis and evaluation of a novel toolkit for biology and biotechnology based on adenine nucleotides analogs

    Call: SONATA BIS 5 , Panel: ST5

    Principal investigator: dr hab. Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki