Projects funded by the NCN

New platinum and rhodium complexes with bulky N-heterocyclic carbene ligands - synthesis, structure and catalytic activi...

Call: SONATA 12 , Panel: ST5

Principal investigator: dr Patrycja Żak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

The role of E3 ligase complexes in integration of protein homeostasis and aging.

Call: OPUS 12 , Panel: NZ3

Principal investigator: dr Wojciech Pokrzywa

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Novel multi-target directed ligands combining cholinesterase inhibition and 5-HT6 antagonism - design, synthesis and pha...

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Anna Więckowska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Modeling of structure of gamma-aminobutyric acid transporters as an essential biological and therapeutic target

Call: SONATA 12 , Panel: NZ7

Principal investigator: dr hab. Marek Bajda

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Toward new family of polynuclear zinc clusters supported by 8-hydroksyquinoline derivatves and related photoactive ligan...

Call: OPUS 1 , Panel: ST5

Principal investigator: dr Iwona Justyniak

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Quantum nanomagnets based on metal complexes with unusual geometries and using new unusual ligands

Call: SONATA BIS 6 , Panel: ST5

Principal investigator: dr Dawid Pinkowicz

Uniwersytet Jagielloński, Wydział Chemii

The role of halogen bonding in interaction of ligands with SERT.

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Jakub Staroń

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Application of approximate non-empirical model based on long-range terms of interaction energy for assessment of inhibit...

Call: PRELUDIUM 11 , Panel: ST4

Principal investigator: Wiktoria Jedwabny (z d. Giedroyć-Piasecka)

Politechnika Wrocławska, Wydział Chemiczny

The optically pure aziridine rings as highly effective units to transfer of chirality to racemic or prochiral reagents. ...

Call: OPUS 11 , Panel: ST5

Principal investigator: dr hab. Michał Rachwalski

Uniwersytet Łódzki, Wydział Chemii

Development of method based on fluorescence polarization for high affinity ligand searching toward m7G nucleotide bindin...

Call: PRELUDIUM 11 , Panel: ST4

Principal investigator: Anna Wojtczak

Uniwersytet Warszawski, Wydział Fizyki

Synthesis and biological evaluation of novel, drug-like multifunctional ligands, as potential anti-Alzheimer's agents ta...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Dawid Panek

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Rational design of molecular nanomagnets: synthesis, characterization, theoretical description and computational modelin...

Call: OPUS 11 , Panel: ST4

Principal investigator: prof. Czesław Rudowicz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Imine Cage-like Silsesquioxane as New Multifunctional Ligands in Supramolecular Chemistry.

Call: PRELUDIUM 11 , Panel: ST5

Principal investigator: dr Mateusz Janeta

Uniwersytet Wrocławski, Wydział Chemii

The determination of ADME-Tox in vitro for potential CNS-drug candidates acting as potent and selective ligands of serot...

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Annamaria Lubelska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Synthesis and pharmacological characterization of structurally diverse chemical analogues of compound PO-10 as multiple ...

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Zagórska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi...

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Małgorzata Filip

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Multifunctional inhibitors of beta-secretase with anti-aggregating properties of neurotoxic peptides - beta-amyloid and ...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Barbara Malawska

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

The effect of peroxisome proliferator activated receptor (PPAR) gamma ligands on cytokines synthesis in the porcine myom...

Call: PRELUDIUM 11 , Panel: NZ9

Principal investigator: dr Aleksandra Kurzyńska

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Investigating the ubiquitylation network of Irc20 and Tfb3 ubiquitin ligases needed upon DNA damage

Call: SONATA 11 , Panel: NZ1

Principal investigator: dr Ewa Błaszczak

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Rekonstrukcja ścieżek dyfuzji liganda z białka

Call: ETIUDA 4 , Panel: ST3

Principal investigator: Jakub Rydzewski

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Karolina Podkowa

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

The hydrophobic solvation of halogenated compounds. Thermodynamic study on contribution of halogen bonding in intermolec...

Call: OPUS 10 , Panel: ST4

Principal investigator: prof. Jarosław Poznański

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Synthesis and physicochemical properties of H- and Π-shaped mesogens - ligands for modification of gold nanoparticles su...

Call: PRELUDIUM 1 , Panel: ST5

Principal investigator: dr Milena Kołpaczyńska

Uniwersytet Warszawski, Wydział Chemii

Memetic algorithms for the excited ligand diffusion in condensed biological matter

Call: PRELUDIUM 10 , Panel: ST3

Principal investigator: Jakub Rydzewski

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Synthesis of new metathesis catalysts with modified N-heterocyclic carbene ligands

Call: PRELUDIUM 1 , Panel: ST5

Principal investigator: Agnieszka Hryniewicka

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

Synthesis of new palladium and ruthenium complexes bearing monoaminocarbene ligands and investigation of their catalytic...

Call: PRELUDIUM 10 , Panel: ST5

Principal investigator: Jan Lorkowski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

5-HT6 receptor ligands as addition to antipsychotic therapy in schizophrenia - an impact on body weight, metabolic param...

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Anna Wesołowska

Uniwersytet Jagielloński Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

Call: OPUS 10 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Synthesis and Struktural Characterization of Small-Molecule Probes for the Programmed Death 1/ Programmed Death Ligand 1...

Call: PRELUDIUM 10 , Panel: ST5

Principal investigator: Katarzyna Guzik

Uniwersytet Jagielloński, Wydział Chemii

Expression and engineering of a novel laccase from Fusarium oxysporum and its potential in brown coal biosolubilisation

Call: PRELUDIUM 10 , Panel: NZ9

Principal investigator: Natalia Kwiatos

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Reversible modification of enzyme activity and substrate specificity by engineering of the ligand exchange pathways

Call: HARMONIA 7 , Panel: NZ1

Principal investigator: dr Artur Góra

Politechnika Śląska, Centrum Biotechnologii

Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Call: HARMONIA 7 , Panel: NZ7

Principal investigator: Sabina Podlewska

Instytut Farmakologii PAN

New olefin metathesis catalysts containig a nitro group on the N-heterocyclic ligand

Call: PRELUDIUM 9 , Panel: ST5

Principal investigator: dr Marta Malinowska

Uniwersytet w Białymstoku, Wydział Biologiczno-Chemiczny

Traizine 5-HT6 receptor ligands - new perspective for therapy of current civilization CNS-diseases

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr hab. Jadwiga Handzlik

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

Quaternary pyridinium salts- new ligands in te complexation process of metal ions in a biphasic system

Call: PRELUDIUM 9 , Panel: ST8

Principal investigator: Aleksandra Wojciechowska

Politechnika Poznańska, Wydział Technologii Chemicznej

Understanding the mechanism of ubiquitin-mediated proteolysis of the MAPKKK18 kinase

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: Małgorzata Tajdel-Zielińska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig...

Call: SONATA 1 , Panel: NZ2

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN