Projects funded by the NCN


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320 projects found matching your search criteria :

  1. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  2. The role of glycosylation of structural proteins in the life cycle of SARS-CoV-2 coronavirus.

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: dr hab. Ewelina Król

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  3. Effect of SSR 504734, a selective glycine transporter type 1 inhibitor, on seizure activity and therapeutic efficacy of ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Piotr Wlaź

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  4. The study of adsorption mechanisms of N-benzenamino(boronphenyl)methylphosphonic acids on different metal surfaces

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: dr Natalia Piergies

    Uniwersytet Jagielloński, Wydział Chemii

  5. An influence of lipoproteins on fibrinolysis and pleiotropic effect of proprotein convertase subtilisin/kexin type 9 (PC...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Magdalena Kopytek

    Krakowski Szpital Specjalistyczny im. Jana Pawła II

  6. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  7. Synthetic epidermal growth factor receptor inhibitor conjugated with nobel metal nanoparticles as a potential drug for t...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Shaoshan Mai

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  8. The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Magdalena Żarnik

    Uniwersytet Jagielloński, Wydział Chemii

  9. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Dawid Panek

    Uniwersytet Jagielloński, Collegium Medicum

  10. Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera...

    Call: WEAVE-UNISONO , Panel: NZ7

    Principal investigator: prof. Stefan Karol Chłopicki

    Uniwersytet Jagielloński

  11. Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

    Call: OPUS 20 , Panel: NZ4

    Principal investigator: prof. Bożena Kamińska-Kaczmarek

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  12. Cell-to-cell transmission of SARS-CoV2 virus

    Call: PRELUDIUM BIS 2 , Panel: NZ6

    Principal investigator: prof. Krystyna Bieńkowska-Szewczyk

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  13. Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Adam Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  14. Comparison of the mechanism of action of valproic acid and levetiracetam as histone deacetylase inhibitors in ovarian ca...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Patrycja Kwiecińska

    Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

  15. Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the c...

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Artur Góra

    Politechnika Śląska, Centrum Biotechnologii

  16. Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Anna Mrozek-Wilczkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  17. Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Tomasz Wróbel

    Uniwersytet Medyczny w Lublinie

  18. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  19. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  20. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Ewa Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

  21. Changes in lipid metabolism of resistant to BRAF/MEK inhibitors human melanoma cells associated with the presence of adi...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Aleksandra Simiczyjew

    Uniwersytet Wrocławski, Wydział Biotechnologii

  22. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  23. Modulation of ATP production using glycolysis inhibitors in cancer cells monitored by novel biosensing systems based on ...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Katarzyna Ratajczak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  24. Role of cereal leaf beetle – associated bacteria in the adaptation of their insect host to the insecticides and protease...

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: Beata Wielkopolan

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  25. Exploring the allosteric regulation of the SARS CoV-2 hydrolases using methyl-TROSY NMR spectroscopy - in search of nove...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wiktor Koźmiński

    Uniwersytet Warszawski, Wydział Chemii

  26. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  27. Structure optimization of the PD-1/PD-L1 inhibitors based on the terphenyl scaffold

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: dr Damian Muszak

    Uniwersytet Jagielloński, Wydział Chemii

  28. Epigenetic regulation of expression of genes involved in extracellular matrix remodeling and angiogenesis during develop...

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: dr Radosław Maksym

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  29. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Marek Jamrozik

    Uniwersytet Jagielloński, Collegium Medicum

  30. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  31. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  32. Inhalable polymeric delivery systems of antibiotics and quorum sensing inhibitors for the treatment of respiratory infec...

    Call: OPUS 18 , Panel: ST5

    Principal investigator: prof. Elżbieta Pamuła

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

  33. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Karaś

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  34. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Burchacka

    Politechnika Wrocławska

  35. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  36. Development of a three-dimensional in vitro model for studying the mechanisms of immunostimulatory activity of PD-1/PD-L...

    Call: PRELUDIUM 18 , Panel: NZ5

    Principal investigator: Justyna Kocik

    Uniwersytet Jagielloński, Wydział Chemii

  37. Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Karolina Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  38. A new approach of vision restoration based on modified Rabies virus tracing technique

    Call: SONATA BIS 9 , Panel: NZ5

    Principal investigator: dr Andrzej Foik

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  39. Restoration of beta-cell function via inhibition of diabetic kinome.

    Call: SONATA BIS 9 , Panel: NZ1

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński

  40. Crystallography of DNA repair enzymes as a tool to study substrate specifity and a mechanism of inhibition

    Call: HARMONIA 1 , Panel: NZ1

    Principal investigator: prof. Barbara Tudek

    Instytut Biochemii i Biofizyki PAN

  41. The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

    Call: SONATA BIS 9 , Panel: NZ6

    Principal investigator: dr Alina Minias

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  42. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Aneta Rogalska

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  43. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  44. Effect of therapy with selective serotonin reuptake inhibitors and physical exercise on blood brain barrier permeability...

    Call: PRELUDIUM 17 , Panel: NZ5

    Principal investigator: Marta Małkiewicz

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Oddziałem Pielęgniarstwa i Instytutem Medycyny Morskiej i Tropikalnej

  45. Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

    Call: PRELUDIUM 17 , Panel: NZ5

    Principal investigator: Brygida Marczyk

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  46. The role of inflammatory and anti-inflammatory cytokines in the process of epileptogenesis and their interaction with in...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr Piotr Maciejak

    Instytut Psychiatrii i Neurologii

  47. Effects of proteasome inhibition on mitochondrial homeostasis.

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Agnieszka Chacińska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  48. Radiolabelled peptidomimetic inhibitors of the VEGF/NRP-1 complex for imaging of pathological angiogenesis associated wi...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Aleksandra Misicka-Kęsik

    Uniwersytet Warszawski

  49. Połączone działanie agonistów receptorów adenozynowych i antagonistów receptora P2Y12 zwiększa hamowanie funkcji płytek ...

    Call: ETIUDA 7 , Panel: NZ3

    Principal investigator: Nina Wolska

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  50. Development of new and more efficient treatment against mesothelioma utilizing oncolytic adenovirus armed with ICOS liga...

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny