Projects funded by the NCN


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Optical and time-resolved spectroscopy for hypothesis veryfication of the conducting by mTS the reductive reaction with THF utilization as a cofactor and for description of the inhibition mechanism of the mTS activity by chosen inhibitors.

2017/25/N/NZ1/01535

Keywords:

thymidylate synthase reaction uncoupling mTHF THF dUMP FdUMP N-4OH-dCMP absorption spectroscopy emission spectroscopy time-resolved spectroscopy

Descriptors:

  • NZ1_3: Biophysics
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Wydział Fizyki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Małgorzata Prokopowicz 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 58 320 PLN

Project start date (Y-m-d): 2018-03-05

Project end date (Y-m-d): 2019-09-04

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.