Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Studies of alkylation mechanism of DNA oligomers using new Top I inhibitors from camptothecin family by physical organic methods and bioassays in terms of application in targeted oncological chemotherapy

2017/27/B/ST4/00190

Keywords:

mechanism of targeted chemotherapy new camptothecin derivatives NMR MS X-Ray CD DNA alkylation bioassays in vitro

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST5_16:
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Narodowy Instytut Leków

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Lech Kozerski 

Number of co-investigators in the project: 6

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 1 066 484 PLN

Project start date (Y-m-d): 2018-10-31

Project end date (Y-m-d): 2023-09-29

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.