Projects funded by the NCN

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196 projects found matching your search criteria :

  1. Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  2. Impact of selective modulators of estrogen and aryl hydrocarbon receptors on hypoxia/ischemia-induced neuronal cell dama...

    Call: PRELUDIUM 1 , Panel: NZ3

    Principal investigator: Joanna Rzemieniec

    Instytut Farmakologii PAN

  3. EFFECTS OF ADENOSINE A2A RECEPTOR LIGANDS ON BEHAVIORAL EFFECTS OF ABUSED DRUG (COCAINE) AND NATURAL REWARD (FOOD) USING...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Karolina Agnieszka Wydra

    Instytut Farmakologii PAN

  4. Plasticity of glutamatergic synapses on dopamine neurons: the mechanism of habit formation.

    Call: HARMONIA 3 , Panel: NZ4

    Principal investigator: dr hab. Jan Manuel Rodriguez-Parkitna

    Instytut Farmakologii PAN

  5. Effects of restraint stress on properties of neurons and synaptic transmission in hypothalamic paraventricular nucleus o...

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: Magdalena Joanna Kusek

    Instytut Farmakologii PAN

  6. Examine the importance of intracellular pathways in the action of opioids in microglial cells in vitro

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  7. Neural mechanisms underlying pathology of motivation.

    Call: SONATA BIS 2 , Panel: NZ3

    Principal investigator: dr Jan Manuel Rodriguez-Parkitna

    Instytut Farmakologii PAN

  8. The effect of enriched environment on the epigenetic mechanism in neurodevelopmental model of schizophrenia.

    Call: PRELUDIUM 4 , Panel: NZ4

    Principal investigator: dr Ewelina Bator

    Instytut Farmakologii PAN

  9. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Karolina Kamińska

    Instytut Farmakologii PAN

  10. Wykorzystanie metod uczenia maszynowego w zadaniach komputerowo wspomaganego projektowania leków.

    Call: ETIUDA 3 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  11. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Maria Nalepa

    Instytut Farmakologii PAN

  12. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  13. Fingerprint Połączeń Podstrukturalnych - nowa metoda reprezentacji związków chemicznych

    Call: ETIUDA 4 , Panel: NZ2

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  14. Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  15. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii PAN

  16. The role of synovial fibroblasts' activity in joint pain in osteoarthritis

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  17. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Justyna Józefa Brodowicz

    Instytut Farmakologii PAN

  18. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  19. The role of endoplasmic reticulum stress in the pathomechanisms of early-life stress-induced dysfunction of the prefrona...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Chocyk

    Instytut Farmakologii PAN

  20. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii PAN

  21. The developmental changes in the endogenous opioid system associated with altered sensitivity to reward during adolescen...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Klaudia Weronika Misiołek

    Instytut Farmakologii PAN

  22. Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  23. Modeling Progression of α-Synucleinopathy in Noradrenergic and Serotonergic Systems – Possible Link with Prodromal Sympt...

    Call: PRELUDIUM 23 , Panel: NZ4

    Principal investigator: Anna Hajam Alwani

    Instytut Farmakologii PAN

  24. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  25. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  26. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Eryka Gawlińska

    Instytut Farmakologii PAN

  27. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii PAN

  28. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  29. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  30. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  31. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  32. Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Katarzyna Anna Chamera

    Instytut Farmakologii PAN

  33. Evaluation of histopathological changes in the rats tissues after acute and chronic administration of the compounds from...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Edyta Dorota Możdżeń

    Instytut Farmakologii PAN

  34. Pessimism as cognitive biomarker of depression in animal model

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  35. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  36. Molecular mechanism of unique action of clozapine in the context of GPCR.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Agata Faron-Górecka

    Instytut Farmakologii PAN

  37. Contribution of nitrergic transmission in the modulation of L-dopa activity in the rat 6-OHDA model of Parkinson's disea...

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Elżbieta Kazimiera Lorenc-Koci

    Instytut Farmakologii PAN

  38. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  39. The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Danuta Jantas

    Instytut Farmakologii PAN

  40. The group III metabotropic glutamate receptors as a target for future antypsychotic drugs

    Call: MAESTRO 3 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii PAN

  41. "Epigenetic mechanisms underlying cocaine seeking and relapse"

    Call: MAESTRO 3 , Panel: NZ3

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  42. PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

    Call: SONATA BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  43. Neurobiology of optimism; Characterisation of the neuroanatomical and neurochemical substrates of cognitive judgement bi...

    Call: SONATA BIS 2 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  44. The research of molecular markers for neuroprotective effect of tetrahydroisoquinolines based on various eksperimental m...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr Agnieszka Wąsik

    Instytut Farmakologii PAN

  45. The effects of positive allosteric modulators of alpha7 nicotinic acetylcholine receptors on complex cognitive processes...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Nikiforuk

    Instytut Farmakologii PAN

  46. The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairmen...

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: dr hab. Mariusz Papp

    Instytut Farmakologii PAN

  47. Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: dr hab. Jadwiga Wardas

    Instytut Farmakologii PAN

  48. The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii PAN

  49. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  50. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

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