Projects funded by the NCN

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196 projects found matching your search criteria :

  1. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Ludwika Haduch

    Instytut Farmakologii PAN

  2. Effects of ketamine optical isomers on motivation and decision-making in rats using deep learning for behavioral analysi...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Natalia Alicja Malikowska-Racia

    Instytut Farmakologii PAN

  3. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii PAN

  4. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii PAN

  5. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii PAN

  6. Investigation of novel functionally selective opioid receptors agonists

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Łucja Elżbieta Szumiec

    Instytut Farmakologii PAN

  7. Effects of prenatal stress on properities of neurons and synaptic transmission in dorsal raphe nucleus of the rat

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Joanna Grażyna Sowa

    Instytut Farmakologii PAN

  8. The effect of chronic treatment with iasenapine and iloperidone on the expression and activity of cytochrome P450 in the...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Przemysław Jan Danek

    Instytut Farmakologii PAN

  9. Effects of a novel nonaddictive opioid on response to stress

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: dr Łucja Elżbieta Szumiec

    Instytut Farmakologii PAN

  10. Impact of endocrine disrupting chemicals - 4,para nonylphenol - on toxic effects mediated by xenobiotic receptors PXR an...

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Ewa Joanna Litwa

    Instytut Farmakologii PAN

  11. Define the role and modulation of immune diabetes changed factors - their importance to the action of analgesics.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Magdalena Małgorzata Żychowska

    Instytut Farmakologii PAN

  12. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii PAN

  13. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  14. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Stanisław Detka

    Instytut Farmakologii PAN

  15. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  16. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  17. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  18. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  19. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  20. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  21. Adaptacyjne podejmowanie decyzji u zwierząt z komórkowo specyficzną inaktywacją receptorów glutaminianu w układzie dopam...

    Call: ETIUDA 4 , Panel: NZ4

    Principal investigator: Przemysław Eligiusz Cieślak

    Instytut Farmakologii PAN

  22. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  23. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii PAN

  24. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  25. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Agata Zygmunt

    Instytut Farmakologii PAN

  26. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  27. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Zofia Kuter

    Instytut Farmakologii PAN

  28. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii PAN

  29. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  30. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Bernadeta Szewczyk

    Instytut Farmakologii PAN

  31. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Katarzyna Elżbieta Głombik

    Instytut Farmakologii PAN

  32. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Józef Wilczkowski

    Instytut Farmakologii PAN

  33. Novel hope for diseased joints: a polymer-based treatment to promoteregenerative strategies for patients with osteoarthr...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marta Kędziora

    Instytut Farmakologii PAN

  34. Biological roles of transcriptional networks activated in the brain by psychotropic drugs

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii PAN

  35. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  36. Reinforcement sensitivity phenotypes as determinants of various motivational styles of alcohol drinking: craving for rew...

    Call: OPUS 28 , Panel: HS6

    Principal investigator: prof. Rafał Ryguła

    Instytut Farmakologii PAN

  37. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Izabela Trojan

    Instytut Farmakologii PAN

  38. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: dr Magdalena Joanna Zaniewska

    Instytut Farmakologii PAN

  39. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Dariusz Marek Żurawek

    Instytut Farmakologii PAN

  40. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi...

    Call: PRELUDIUM 9 , Panel: ST6

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  41. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

  42. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii PAN

  43. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  44. The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Basińska-Ziobroń

    Instytut Farmakologii PAN

  45. Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało...

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Joanna Ewa Sowa

    Instytut Farmakologii PAN

  46. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  47. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  48. Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  49. The role of glucocorticoids in the regulaton of neurodegenerative prosses

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Anna Jadwiga Kurek

    Instytut Farmakologii PAN

  50. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

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