Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Membrane stretch regulation of mitochondrial potassium channel: role in fusion and fission?

2017/26/M/NZ3/00727

Keywords:

mitochondria ion channel mechanosensitive fusion fission apoptosis

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology
  • NZ1_3: Biophysics

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Koprowski 

Number of co-investigators in the project: 5

Call: HARMONIA 9 - announced on 2017-06-14

Amount awarded: 768 000 PLN

Project start date (Y-m-d): 2018-05-08

Project end date (Y-m-d): 2022-05-07

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. The monomers, oligomers, and fibrils of amyloid-β inhibit the activity of mitoBKCa channels by a membrane-mediated mechanism
    Authors:
    Yevheniia Kravenska, Hanna Nieznanska, Krzysztof Nieznanski, Elena Lukyanetz, Adam Szewczyk, Piotr Koprowski
    Academic press:
    BBA Biomembranes (rok: 2020, tom: 1862(9), strony: 183337), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2020.183337 - link to the publication
  1. Membrane - mediated modulation of the activity of mitochondrial calcium-activated potassium channel of large conductance
    Authors:
    Piotr Koprowski, Yevheniia Kravenska, Agnieszka Walewska, Hanna Nieznanska, Krzysztof Nieznanski, Adam Szewczyk
    Conference:
    Targeting Mitochondria, 10th Anniversary (rok: 2019, ), Wydawca: Archives on the World Mitochondria Society
    Data:
    konferencja 43766
    Status:
    Published
  2. Mitochondria shape changes and the inner membrane-located mechanosensor, mitoBK(ca) - a hypothesis"
    Authors:
    Agnieszka Walewska, Piotr Koprowski, Adam Szewczyk
    Conference:
    Quantitative Aspects of Membrane Fusion and Fission, Biophysical Society (USA) Thematic meeting (rok: 2019, ), Wydawca: Biophysical Society
    Data:
    konferencja 43591
    Status:
    Published
  3. Short and long forms of amyloid-β inhibit mitochondrial large-conductance calcium-activated potassium channel
    Authors:
    Kravenska Y., Nieznanska H., Nieznanski K., Szewczyk A., Koprowski P.
    Conference:
    8th Mitochondrion (rok: 2020, ), Wydawca: Instytut Biologii Doświadczalnej
    Data:
    konferencja 0.5.02.2020
    Status:
    Published