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1. Structure-activity relationship of bifunctional peptides, agonists of opioid receptors and antagonists of neurokinin rec…

Principal investigator: Jolanta Dyniewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 2, Panel: ST5

2. Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 2, Panel: NZ1

3. Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological …

Principal investigator: dr Justyna Piekielna-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: SONATA 14, Panel: ST5

4. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Principal investigator: dr Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ4

5. Gene and protein analysis of OPRM1/MOR and OPRK1/KOR opioid receptors expression and neurobiological marker of nerve ter…

Principal investigator: Piotr Kazimierz Kupczyk

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 1, Panel: NZ4

6. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic …

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: OPUS 23, Panel: NZ7

7. The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc…

Principal investigator: dr Marta Zielińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: SONATA 15, Panel: NZ7

8. Investigation of novel functionally selective opioid receptors agonists

Principal investigator: Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Call: ETIUDA 8, Panel: NZ7

9. Kappa opioid receptors integrate neuronal signaling involved in social behavior

Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 18, Panel: NZ7

10. MOLECULAR DETERMINANTS OF SIGNAL PROPAGATION IN THE DELTA AND MU OPIOID RECEPTORS - IN SEARCH FOR ANALGETICS WITH LESS S…

Principal investigator: Tomasz Maciej Stepniewski

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM 14, Panel: NZ2

11. Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept…

Principal investigator: prof. Anna Ewa Janecka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 9, Panel: ST5

12. Role of opioid receptors in arterial hypertension. Examination of hypotensive action of biphalin, a synthetic non-addtic…

Principal investigator: prof. Janusz Bogumił Sadowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 2, Panel: NZ4

13. Rational design and evaluation of functionally biased opioid agonists

Principal investigator: prof. Ryszard Przewłocki

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

14. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

Call: OPUS 15, Panel: NZ7

15. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

16. Neurobiological mechanisms of migraine pain - role of opioid and NOP systems

Principal investigator: dr hab. Katarzyna Małgorzata Targowska-Duda

Uniwersytet Medyczny w Lublinie

Call: SONATA BIS 11, Panel: NZ7

17. Fentanyl opioid designer drugs: from molecular modeling to in vitro studies

Principal investigator: prof. Joanna Sadlej

Narodowy Instytut Leków

Call: OPUS 6, Panel: ST4

18. NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

Principal investigator: Arkadiusz Bogumił Leniak

Instytut Farmakologii PAN

Call: PRELUDIUM 24, Panel: NZ7

19. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Call: SONATA 17, Panel: NZ5

20. Effects of a novel nonaddictive opioid on response to stress

Principal investigator: dr Łucja Elżbieta Szumiec

Instytut Farmakologii PAN

Call: PRELUDIUM 17, Panel: NZ7

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