The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – focusing on different types of cell death and cell-cell interactions

2019/35/D/NZ7/02830

Keywords

Descriptors

  • NZ7_014: Farmacja, farmakoterapia, farmakologia
  • NZ4_004: Patofizjologia ogólna
  • NZ5_003: Patogeneza chorób człowieka

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Marta Zielińska

Number of co-investigators in the project: 3

Call

SONATA 15 – announced on 2019-09-16

Amount awarded
1 556 040 PLN
Project start date
2020-11-30
Project end date
2026-11-29
Project duration
72 months (the same as in the proposal)
Project status
Pending project

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Positive allosteric modulation of µ-opioid receptor – A new possible approach in the pain management?

    Authors:
    Wojciech Król , Weronika Machelak , Marta Zielińska
    Academic press:
    Biochemical Pharmacology (year: 2024, volume: 232, pages: 116686), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bcp.2024.116686 – link to the publication
  2. The role of kappa opioid receptors in immune system – An overview

    Authors:
    Szczepaniak A, Machelak W, Fichna J, Zielińska M
    Academic press:
    European Journal of Pharmacology (year: 2022, volume: 933, pages: 175214), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2022.175214 – link to the publication
  3. Long non-coding RNAs - SNHG6 emerge as potential marker in colorectal cancer

    Authors:
    Michalina Jurkiewicz, Adrian Szczepaniak, Marta Zielińska
    Academic press:
    Biochim Biophys Acta Rev Cancer (year: 2024, volume: 189, pages: 189056), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbcan.2023.189056 – link to the publication

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