Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – focusing on different types of cell death and cell-cell interactions

2019/35/D/NZ7/02830

Keywords:

cell death colitis colitis associated colorectal cancer endogenous opioid peptides inflammatory bowel diseases KOP receptors opioid receptors

Descriptors:

  • NZ7_014:
  • NZ4_004:
  • NZ5_003:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Zielińska 

Number of co-investigators in the project: 3

Call: SONATA 15 - announced on 2019-09-16

Amount awarded: 1 556 040 PLN

Project start date (Y-m-d): 2020-11-30

Project end date (Y-m-d): 2025-11-29

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Positive allosteric modulation of µ-opioid receptor – A new possible approach in the pain management?
    Authors:
    Wojciech Król , Weronika Machelak , Marta Zielińska
    Academic press:
    Biochemical Pharmacology (rok: 2024, tom: 232, strony: 116686), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bcp.2024.116686 - link to the publication
  2. Long non-coding RNAs - SNHG6 emerge as potential marker in colorectal cancer
    Authors:
    Michalina Jurkiewicz, Adrian Szczepaniak, Marta Zielińska
    Academic press:
    Biochim Biophys Acta Rev Cancer (rok: 2024, tom: 189, strony: 189056), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbcan.2023.189056 - link to the publication
  3. The role of kappa opioid receptors in immune system – An overview
    Authors:
    Szczepaniak A, Machelak W, Fichna J, Zielińska M
    Academic press:
    European Journal of Pharmacology (rok: 2022, tom: 933, strony: 175214), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2022.175214 - link to the publication

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