Projects funded by the NCN

Investigation of the mechanism of enhanced liposome delivery to tumors and its application for dual target immunotherapy

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Environmental modulation of CDK4/6 inhibitor efficacy: Impact of mycotoxin alternariol exposure on anti-cancer therapies

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Anna Dominika Walczak-Szeffer

Uniwersytet Medyczny w Łodzi

Neutrophil Dynamics: Unveiling Anti-Tumor and Therapy Efficacy with the TUmor Neutrophil Immunotherapy on Chip (TUNIC) m...

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr Martin Nurmik

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Analysis of the effects of proteotoxic stress on cholesterol homeostasis and its associations with cardiovascular diseas...

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Wiesława Elżbieta Widłak

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Parallel microevolution of metabolic plasticity and chemoresistance of cancer cells: a key to understanding cancer relap...

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Jarosław Piotr Czyż

Uniwersytet Jagielloński

Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Biomaterial enriched with propolis extract as a promising chemopreventive dressing material after melanoma excision

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Marta Trzaskowska

Uniwersytet Medyczny w Lublinie

Cellular effects in the tumor microenvironment and the potential for targeted delivery of molecules associated with the ...

Call: OPUS 27 , Panel: NZ4

Principal investigator: prof. Magdalena Maria Staniszewska

Katolicki Uniwersytet Lubelski Jana Pawła II

N6-methyladenine metabolism - potential relationships with the development of hematological malignancies.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Marta Starczak

Uniwersytet Mikołaja Kopernika

Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

Call: PRELUDIUM 23 , Panel: ST5

Principal investigator: Aleksandra Dorota Helbik-Maciejewska

Uniwersytet Gdański

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Identification of novel microRNA biomarkers in liquid biopsy of patients with neuroendocrine tumors

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Paweł Mateusz Komarnicki

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

(Lipid-FLUX) Single-cell lipidomics by spectroscopy: Quantification of the lipid transport through the development of ne...

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Małgorzata Anna Barańska

Uniwersytet Jagielloński

Innovative Small Molecule Inhibitors Targeting LAG-3 and MHCII Complex for Tumour Immunotherapy

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński

Synthesis of novel hybrid nanomaterials based on fullerene scaffold for photodynamic therapy of cancer

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Dominik Jakub Dreszer

UNIWERSYTET ŚLĄSKI

Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Damian Jacenik

Uniwersytet Łódzki

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Controlling the covalent activity of a PD-L1 inhibitors with light

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Wiktor Jan Uzar

Uniwersytet Jagielloński

EGR1 Protein: A Key Factor in Cellular Homeostasis?

Call: PRELUDIUM 23 , Panel: NZ3

Principal investigator: Marta Leśniczak-Staszak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The two are better than one - biferrocenyl ROS generators as intelligent anticancer agents

Call: OPUS 27 , Panel: ST5

Principal investigator: prof. Konrad Maciej Kowalski

Uniwersytet Łódzki

Interrogation of the antigen presentation dynamics via MHCII in tumor immune evasion through multimodal single-cell sequ...

Call: SONATINA 8 , Panel: NZ2

Principal investigator: dr Natalia Ochocka-Lewicka

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

Call: SONATA 2 , Panel: NZ7

Principal investigator: dr Sebastian Demkowicz

Politechnika Gdańska

CAR(dio)-T(oxicity)- Engineered Heart Tissue model for CAR-T cardiotoxicity evaluation

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Agnieszka Joanna Zimna

Instytut Genetyki Człowieka PAN

Computational methods for understanding tumor immune microenvironment from spatial imaging data

Call: SONATA 19 , Panel: NZ2

Principal investigator: dr Krzysztof Kamil Gogolewski

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Pogoda

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

To be or not to be modified: the role of single m6A sites of long noncoding RNAs in breast cancer

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Elżbieta Wanowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Organometallic (Fe, Ru, Ir, Os) phospho-inducers of drug-resistant cancer cells' ferroptosis

Call: OPUS 26 , Panel: ST4

Principal investigator: dr hab. Urszula Katarzyna Komarnicka

Uniwersytet Wrocławski, Wydział Chemii

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Exploring the influence of genomic features on mutational signatures across tumors

Call: OPUS 26 , Panel: NZ2

Principal investigator: dr Damian Michał Wójtowicz

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Design and characterisation of sealing materials of prosthetic obturator being additionally a cytostatic drug reservoir....

Call: OPUS 26 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Witold Szaflarski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

Call: SONATA BIS 13 , Panel: NZ7

Principal investigator: dr hab. Miłosz Ruszkowski

Instytut Chemii Bioorganicznej PAN

Searching for novel regulators of antitumor immune response

Call: MAESTRO 15 , Panel: NZ6

Principal investigator: dr hab. Magdalena Hanna Winiarska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

XAICancer: Explainable Artificial Intelligence for Cancer Imaging

Call: SONATA BIS 13 , Panel: ST6

Principal investigator: dr Neo Christopher Chung

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Development of novel bifunctional ceramic coatings with osteoinductive and anti-oncogenic properties on metallic implant...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Balbina Karina Makurat-Kasprolewicz

Politechnika Gdańska

Multifunctional emulsion-based transporters for personalised cancer treatment

Call: OPUS 25 , Panel: ST8

Principal investigator: prof. Ewa Dłuska

Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej

Predictive Potential of Circulating MicroRNA Biomarkers in Patients with High Familial or Genetic Risk of Cancer

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Efficiency biomarkers in photodynamic therapy against lung cancer

Call: PRELUDIUM 2 , Panel: NZ4

Principal investigator: dr Martyna Krzykawska-Serda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

The study of the effect of hypoxia on the metabolism of exogenous ferritin and its role in the regulation of free iron i...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: dr Małgorzata Maria Kubiak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Centrum Immunoterapii Komórkowych

The design and development of the peptide inhibitors library targeting Zn(II)-binding site of matrix metalloproteinases ...

Call: PRELUDIUM 22 , Panel: ST5

Principal investigator: Paulina Alicja Potok

Uniwersytet Wrocławski, Wydział Chemii

Molecular profiling of soft tissue sarcomas in tumor and peripheral blood in terms of response to treatment and early de...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Piotr Łukasz Rutkowski

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Are bisphenol S and F safe substitutes for bisphenol A in the face of environmental contamination with estrogenic mycoto...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marta Justyna Kozieł

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr hab. Angelika Muchowicz

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Targeting undruggable proteins involved in tumorigenesis – developing and characterization of advanced nanoplatform for ...

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr hab. Monika Bzowska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Bitechnologii

3D-printed bone implants - Exploring the relationship between the chemical and spatial structure of implants and their s...

Call: OPUS 25 , Panel: ST4

Principal investigator: prof. Edyta Proniewicz

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Odlewnictwa

Spatial Determinants of Immunotherapy Resistance in Cancer

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marta Krawczyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

Call: OPUS 24 , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska