Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The triangle: carotenoids-retinoids-cytochromes plays a key role in development and progress of cancer

2021/43/B/ST4/01547

Keywords:

Raman spectroscopy Raman imaging cancers carotenoids retinoids cytochromes oxidative phosphorylation apoptosis

Descriptors:

  • ST4_002:
  • NZ1_002:
  • NZ1_003:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Łódzka

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Halina Abramczyk 

Number of co-investigators in the project: 9

Call: OPUS 22 - announced on 2021-09-15

Amount awarded: 1 494 317 PLN

Project start date (Y-m-d): 2022-06-07

Project end date (Y-m-d): 2026-06-06

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Effect of COVID-19 mRNA Vaccine on Human Lung Carcinoma Cells In Vitro by Means of Raman Spectroscopy and Imaging
    Authors:
    Halina Abramczyk, Jakub Surmacki
    Academic press:
    ACS Omega (rok: 2023, tom: 8, strony: 42555-42564), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acsomega.3c05287 - link to the publication
  2. Decoding the role of cytochrome c in metabolism of human spermatozoa by Raman imaging
    Authors:
    Halina Abramczyk, Bogna Sobkiewicz, Renata Walczak-Jędrzejowska, Katarzyna Marchlewska, Jakub Surmacki
    Academic press:
    Frontiers in Cell and Developmental Biology (rok: 2022, tom: 10, strony: 45667), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcell.2022.983993 - link to the publication
  3. Control of Mitochondrial Electron Transport Chain Flux and Apoptosis by Retinoic Acid: Raman Imaging In Vitro Human Bronchial and Lung Cancerous Cells
    Authors:
    Halina Abramczyk, Jakub Surmacki
    Academic press:
    Cancers (rok: 2023, tom: 15, strony: 45676), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers15184535 - link to the publication
  4. Raman imaging and chemometric methods in human normal bronchial and cancer lung cells: Raman biomarkers of lipid reprogramming
    Authors:
    Monika Kopeć, Karolina Beton-Mysur, Halina Abramczyk
    Academic press:
    Chemistry and Physics of Lipids (rok: 2023, tom: 257, strony: 45670), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chemphyslip.2023.105339 - link to the publication
  5. Hemoglobin and cytochrome c. reinterpreting the origins of oxygenation and oxidation in erythrocytes and in vivo cancer lung cells
    Authors:
    Halina abramczyk, Jakub Maciej Surmacki, Monika Kopeć, Karolina Jarczewska, Beata Romanowska-Pietrasiak
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 45672), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-41858-z - link to the publication
  6. Confocal Raman imaging reveals the impact of retinoids on human breast cancer via monitoring the redox status of cytochrome c
    Authors:
    Jakub Maciej Surmacki, Halina Abramczyk
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 45668), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-42301-z - link to the publication

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