Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Extracellular vesicles carrying microRNA in experimental immunotherapy for glioblastoma

2021/41/B/NZ6/02436

Keywords:

Cancer immunotherapy extracellular vesicles microRNA

Descriptors:

  • NZ5_007:
  • NZ6_008:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jakub Godlewski 

Number of co-investigators in the project: 4

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 2 485 000 PLN

Project start date (Y-m-d): 2022-01-12

Project end date (Y-m-d): 2027-01-11

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (2)
  1. Environmental Hazards and Glial Brain Tumors: Association or Causation?
    Authors:
    Robert P. Ostrowski, Albert Acewicz,Zhaohui He, Emanuela B. Pucko, Jakub Godlewski
    Academic press:
    International Journal of Molecular Sciences (rok: 2025, tom: 26(15), strony: 7425), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms26157425 - link to the publication
  2. Hyperbaric oxygen therapy for the treatment of hypoxic/ischemic injury upon perinatal asphyxia—are we there yet?
    Authors:
    Damian Mielecki, Jakub Godlewski, Elzbieta Salinska
    Academic press:
    Frontiers in Neurology (rok: 2024, tom: 15, strony: 1386695), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fneur.2024.1386695 - link to the publication
  3. Transcriptional rewiring in cancer driven by POLR2A/RPB1: mechanistic insights, non-coding RNA crosstalk, and therapeutic opportunities
    Authors:
    Adrian Szczepaniak, Katarzyna Jaskuła, Marta Zielińska, Jakub Godlewski
    Academic press:
    Frontiers in Pharmacology (rok: 2025, tom: 16, strony: 1745087), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fphar.2025.1745087 - link to the publication
  4. Transcriptomic analysis of the TRP gene family in human brain physiopathology
    Authors:
    Barbara Olejniczak, Arpita Balakrishnan, Justyna Augustyniak, Elżbieta Salińska, Agnieszka Bronisz, Jakub Godlewski
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2025, tom: 18, strony: 1576941), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnmol.2025.1576941 - link to the publication
  5. Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response
    Authors:
    Arpita Balakrishnan, Gabriela Winiarek, Olga Hołówka , Jakub Godlewski, Agnieszka Bronisz
    Academic press:
    Frontiers in Immunology (rok: 2025, tom: 16, strony: 1540431), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2025.1540431 - link to the publication
  6. Tytuł Harnessing immunotherapy: cancer vaccines as novel therapeutic strategies for brain tumor
    Authors:
    Klaudia Kiel, Raziye Piranlioglu, Jakub Godlewski, Agnieszka Bronisz
    Academic press:
    Frontiers in Immunology (rok: 2025, tom: 16, strony: 1588081), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2025.1588081 - link to the publication
  7. Circular RNAs—New Kids on the Block in Cancer Pathophysiology and Management
    Authors:
    Adrian Szczepaniak, Agnieszka Bronisz, and Jakub Godlewski
    Academic press:
    Cells (rok: 2023, tom: 12(4), strony: 552), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12040552 - link to the publication
  8. MiR-128-3p - a gray eminence of the human central nervous system.
    Authors:
    Klaudia Kiel , Sylwia Katarzyna Król , Agnieszka Bronisz , Jakub Godlewski
    Academic press:
    Molecular Therapy Nucleic Acids (rok: 2024, tom: 35(1), strony: 102141), Wydawca: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.omtn.2024.102141 - link to the publication
  1. Abstract 5680: Circular MALAT1 - the new kid on the block in breast-to-brain metastatic cancer
    Authors:
    Adrian Szczepaniak; Agnieszka Bronisz; Jakub Godlewski
    Conference:
    Cancer Research (rok: 2024, tom: AACR Annual Meeting 2024, strony: 84 (6_Supplement): 5680.), Wydawca: American Association for Cancer Research
    Data:
    konferencja 05-10.04.2024
    Status:
    Published
    DOI:
    10.1158/1538-7445.AM2024-5680 - link to the publication
  2. P12.06.A DESCRIPTIVE AND FUNCTIONAL ASSESSMENT OF MHC I-BOUND PEPTIDES PRESENTED ON EXTRACELLULAR VESICLES OF GLIOBLASTOMA CANCER CELLS IN RESPONSE TO ONCOLYTIC VIRUS IMMUNOTHERAPY
    Authors:
    Agnieszka Bronisz , Klaudia Kiel , Arpita Balakrishnan , Maciej Przybylski , E Chiocca , Jakub Godlewski
    Conference:
    Neuro-Oncology (rok: 2024, tom: 19th Meeting of the European Association of Neuro-Oncology, strony: 27 (Supplement_5); Page v67), Wydawca: Oxford University Press on behalf of the Society for Neuro-Oncology
    Data:
    konferencja 17–20.10.2024
    Status:
    Published
    DOI:
    10.1093/neuonc/noae144.219 - link to the publication

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