Projects funded by the NCN


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144 projects found matching your search criteria :

  1. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. New positive allosteric modulators of EAAT2 glutamate transporter as candidates for treatment of neurological and psychi...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Krzysztof Kamiński

    Uniwersytet Jagielloński, Collegium Medicum

  3. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Przepiórska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Partial agonists of alpha-2 adrenoceptors as new perspective of the effective and safe in reducting body weight and obes...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Magdalena Dudek

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  5. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Maciej Spiegel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

  6. Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Maciej Wnuk

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  7. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Florczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  8. Biomedical and chemometric assessment of the new analytical platform in the study of endogenous substances as potential ...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Lucyna Konieczna

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  9. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  10. New immunomodulators of BTLA-HVEM complex as potential therapeutics in systemic lupus erythematosus

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Anna Wardowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  11. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. The role of intestinal CYP2E1 in pathophysiology of the gastrointestinal tract disorders: new therapies for leaky gut sy...

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Maciej Sałaga

    Uniwersytet Medyczny w Łodzi

  14. New graphene-based approach targeting the prion-like propagation of α-synuclein in Parkinson's disease.

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kujawska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  15. New synthetic resveratrol derivatives with potential anti-ageing and anti-cancer properties

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: dr Justyna Mikuła-Pietrasik

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

  16. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  17. New 3-methoxypropanamide derivatives in search of effective substances for the treatment of neurological diseases - epil...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marcin Jakubiec

    Uniwersytet Jagielloński, Collegium Medicum

  18. Development of new implantable drug forms, biodegradable nanofibers containing selected betulin derivatives in order to ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Janusz Kasperczyk

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

  19. The development of the new safe and controlled anticoagulant therapy with the use of cationically-modified polymers in t...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Andrzej Mogielnicki

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  20. New antimycotic polycations - synthesis, chemical characterization, toxicity and antifungal spectrum

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Kamil Kamiński

    Uniwersytet Jagielloński, Wydział Chemii

  21. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Dawid Panek

    Uniwersytet Jagielloński, Collegium Medicum

  22. A new class of antimicrobial compounds. Design, synthesis and study of the mechanism of action.

    Call: PRELUDIUM BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  23. New generation teranostatic nanocarriers for detection, diagnosis andneuroprotective treatment of ischemic stroke brain ...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Piotr Warszyński

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera Polskiej Akademii Nauk

  24. Influence of the route of administration of new psychoactive substances on their metabolic profile

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Magdalena Popławska

    Narodowy Instytut Leków

  25. A new approach to imaging and rapid microbiome identification in evaluation radiotherapy effects

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Dorota Gabryś

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy, Oddział w Gliwicach

  26. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  27. New therapies of opioid use disorder

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Wojciech Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

  28. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Przemysław Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  29. Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Janusz Dąbrowski

    Uniwersytet Jagielloński, Wydział Chemii

  30. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Marek Jamrozik

    Uniwersytet Jagielloński, Collegium Medicum

  31. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  32. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  33. Processing fluid: A new laboratory tool for diagnostic and basic investigation

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Hanna Turlewicz-Podbielska

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  34. New iron chelators from thiosemicarbazone group in photodynamic therapy

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Robert Gawecki

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  35. Fluorine substitution – a new algorithm for increasing biological activity

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Wojciech Pietruś

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  38. Assessment of the hepatoprotective effect of AP39, a new H2S donor, in a model of autoimmune hepatitis in mice.

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Katarzyna Przejczowska-Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  39. Pharmacological modulation of histamine H3 and H4 receptors - a new perspective in the treatment of neuropathic pain

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Katarzyna Popiołek-Barczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. DEVELOPMENT AND VALIDATION OF NEW LC-MS/MS METHOD FOR DETERMINATION OF UNBOUND TACROLIMUS IN PLASMA IN CYP 3A5 EXPRESSOR...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Karola Warzyszyńska

    Warszawski Uniwersytet Medyczny

  41. Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Zofia Mazerska

    Politechnika Gdańska

  42. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Marcin Drop

    Uniwersytet Jagielloński, Collegium Medicum

  43. DEVELOPMENT OF NEW CLASS PHOTOACTIVATED ANTICANCER-ANTIFUNGAL COMPOUNDS: CONJUGATES OF GOLD NANOPARTICLE-SUPPORTED QUINO...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Oleh Demchuk

    Sieć Badawcza ŁUKASIEWICZ - Instytut Farmaceutyczny

  44. Development of new and more efficient treatment against mesothelioma utilizing oncolytic adenovirus armed with ICOS liga...

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny

  45. Gut microbiota dependent modulation of therapeutic response and side effects to irinotecan and new camptothecin analogue...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jerzy Ostrowski

    Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy

  46. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Evaluation of the effects of long-term administration of new anticonvulsant drug-candidate.

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Anna Makuch-Kocka

    Uniwersytet Medyczny w Lublinie, Wydział Nauk o Zdrowiu

  48. Research of a new small-molecule 1,2,4-triazine derivative (MM-129) - assessment of anti-neoplastic activity and safety ...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Dariusz Pawlak

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  49. New derivatives of plant carboxylic acid as active components of biopreparations safe for human and natural environment

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Włodzimierz Lewandowski

    Politechnika Białostocka, Wydział Budownictwa i Nauk o Środowisku

  50. Searching for new mechanisms of substance use or stress disoreders

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: dr Wojciech Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej