Projects funded by the NCN

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151 projects found matching your search criteria :

  1. Cellular and molecular basis of antifungal activity of metallacarboranes against Candida albicans

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Konrad Kubiński

    Katolicki Uniwersytet Lubelski Jana Pawła II

  2. Molecular mechanisms underlying the liver injury induced by ulipristal acetate treatment

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Aleksandra Natalia Łupińska

    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

  3. Analytical methods for the determination of contaminants in dairy products using electrochemical multisensors platform w...

    Call: DAINA 3 , Panel: NZ7

    Principal investigator: dr Krzysztof Robert Noworyta

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  4. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  5. Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Sebastian Demkowicz

    Politechnika Gdańska

  6. Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

    Call: OPUS 26 (LAP) , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  7. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  8. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Magdalena Wujak

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  9. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Danuta Dudzik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  10. Prioritizing diagnostics and therapeutics of human prion diseases through integrative omics

    Call: WEAVE-UNISONO , Panel: NZ2

    Principal investigator: prof. Beata Sikorska

    Uniwersytet Medyczny w Łodzi

  11. Compounds modulating function of telomeric proteins TRF1 and TRF2

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Maciej Wojciech Bagiński

    Politechnika Gdańska, Wydział Chemiczny

  12. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Alex Jun Matsuda

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  14. Unveiling the molecular signature underlying resistance to CD19 CAR-T therapy in malignant cells.

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marta Krawczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  15. Chemosensors with molecularly imprinted polymers for determination of antiviral active drug substances in body fluids - ...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr Krzysztof Robert Noworyta

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  16. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  17. Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Stefano Volinia

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  18. The impact of physical activity on brain resilience to chronic stress and the mediating role of blood-brain barrier.

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: dr Marta Maria Nowacka-Chmielewska

    Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

  19. Novel mechanism of lead toxicity - a perspective of molecular biology

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Natalia Pawlas

    Instytut Medycyny Pracy i Zdrowia Środowiskowego

  20. The assessment of purity and identity confirmation of extracellular vesicles withcapillary electrophoresis

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Aleksandra Steć

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  21. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  22. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  23. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Maciej Spiegel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

  25. PFAS exposure and premature ovarian insufficiency: molecular mechanism.

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Anna Ptak

    Uniwersytet Jagielloński, Wydział Biologii

  26. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Bartłomiej Pochwat

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Understanding the molecular and ecological interactions between viruses and eriophyoid mites

    Call: POLONEZ BIS 1 , Panel: NZ9

    Principal investigator: dr Tobiasz Zygmunt Druciarek

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  28. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Joanna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  29. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  30. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  31. Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro...

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr Łukasz Dariusz Skalniak

    Uniwersytet Jagielloński, Wydział Chemii

  32. New graphene-based approach targeting the prion-like propagation of α-synuclein in Parkinson's disease.

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kujawska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  33. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  34. In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Anna Karolina Pogorzelska

    Narodowy Instytut Leków

  35. Correlations between supramolecular structure, molecular dynamics, physico-chemical stability, and solubility in neat Ac...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Karolina Jurkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  36. Molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotroph...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Wiesław Ziółkowski

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  37. Enzymes of the L-methionine biosynthetic pathway as novel moleculartargets for antifungal chemotherapy

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Iwona Aniela Gabriel

    Politechnika Gdańska, Wydział Chemiczny

  38. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Anna Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  39. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. Development of an in vitro model for the evaluation of phototoxicity of drugs with different affinity to melanin using a...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr hab. Jakub Rok

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

  41. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  42. Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Olga Iga Wronikowska-Denysiuk

    Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

  43. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  44. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Marta Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  45. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Andrzej Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  46. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Eryka Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Allergic inflammation in particular types of work-related asthma in the context of exposure to low and high molecular we...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Agnieszka Anna Lipińska-Ojrzanowska

    Instytut Medycyny Pracy im. prof. dr. med. Jerzego Nofera

  48. Identification of molecular mechanism of Escherichia coli response to antimicrobial blue light inactivation by genome-wi...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: dr Aleksandra Małgorzata Rapacka-Zdończyk

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  49. Individual biological response of breast cancer tumours to proton irradiation in correlation with molecular and microenv...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Julian Czesław Malicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  50. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

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