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8 projects found matching your search criteria:

1. 1. Allosteric inhibitors of proteasome - optimization of the structure of PR39 analogs in order to achieve greater efficien…

   Principal investigator: Małgorzata Giżyńska

   Uniwersytet Gdański, Wydział Chemii

   Call: PRELUDIUM 12, Panel: ST5

2. 2. The search for novel human proteasome inhibitors and fluorogenic substrates.

   Principal investigator: dr Dawid Dębowski

   Uniwersytet Gdański, Wydział Chemii

   Call: SONATA 1, Panel: ST5

3. 3. Determination of arginase-1 as a potential drug target in the treatment of multiple myeloma and in reducing proteasome i…

   Principal investigator: prof. Jakub Adam Gołąb

   Warszawski Uniwersytet Medyczny, Wydział Lekarski

   Call: OPUS 13, Panel: NZ6

4. 4. Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors…

   Principal investigator: prof. Tadeusz Jerzy Robak

   Uniwersytet Medyczny w Łodzi, Wydział Lekarski

   Call: OPUS 12, Panel: NZ5

5. 5. Using X-ray crystallography for localization of the sites of binding of allosteric inhibitors and activators within the …

   Principal investigator: Julia Witkowska

   Uniwersytet Gdański, Wydział Chemii

   Call: PRELUDIUM 9, Panel: NZ1

6. 6. Effects of proteasome inhibition on mitochondrial homeostasis.

   Principal investigator: prof. Agnieszka Małgorzata Chacińska

   Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

   Call: OPUS 17, Panel: NZ5

7. 7. Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass pr…

   Principal investigator: Tadeusz Franciszek Kubicki

   Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

   Call: PRELUDIUM 15, Panel: NZ5

8. 8. Investigation of the antitumor potential of stimulator of interferon genes (STING) - an adaptor protein in innate immune…

   Principal investigator: Olga Sokołowska

   Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

   Call: PRELUDIUM 9, Panel: NZ6