Projects funded by the NCN

Functionalized carbohydrates pharmacophores as a putative antituberculosis drugs - the mechanism of action.

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

The studies on microevolution markers of Mycobacterium bovis BCG Moreau substrain used for BCG immunization against tube...

Call: PRELUDIUM 8 , Panel: NZ7

Principal investigator: Katarzyna Krysztopa-Grzybowska

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

The role of IL8 in pathogenesis of tubercle bacili.

Call: HARMONIA 1 , Panel: NZ6

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Implication of orphan response regulatory proteins in the physiology and virulence of Mycobacterium tuberculosis.

Call: SONATA 6 , Panel: NZ6

Principal investigator: dr Renata Anna Płocińska

Instytut Biologii Medycznej PAN

Identification of the acetyl coenzyme A carboxylation mechanism i pathogenic and nonpathogenic mycobacterial species

Call: PRELUDIUM 3 , Panel: NZ2

Principal investigator: dr Jakub Pawełczyk

Instytut Biologii Medycznej PAN

Inhibitors of the non-mevalonate isoprenoid biosynthesis pathway - a new class of antibiotics against tuberculosis and m...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Ignacy Przemysław Janicki

Centrum Badań Molekularnych i Makromolekularnych PAN

Demonstration of the key role of vitamin B12 uptake in regulating Mycobacterium tuberculosis virulence lipids synthesis ...

Call: SONATA BIS 14 , Panel: NZ6

Principal investigator: dr Jakub Pawełczyk

Instytut Biologii Medycznej PAN

The Potential of Mycobacterium tuberculosis Phase-Specific Antigens for Targeted TB Diagnosis

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr Shima Mahmoudi

Politechnika Śląska

Metabolomic comparison of Mycobacterium tuberculosis and Mycobacterium marinum model organisms in response to antimicrob...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Marcin Karol Ziomek

Uniwersytet Medyczny w Lublinie

Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Make an old drug great again – isoniazid/rifamycin-boron clusters conjugates – synthesis and antitubercular activity....

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

Instytut Biologii Medycznej PAN

Mycobacterium tuberculosis factors affecting the frequency of tuberculosis transmission

Call: OPUS 18 , Panel: NZ7

Principal investigator: prof. Ewa Maria Augustynowicz-Kopeć

Instytut Gruźlicy i Chorób Płuc

Structural insights into the involvement of the RNA degradosome in trans-translation in the light of the antimicrobial a...

Call: SONATA BIS 9 , Panel: NZ1

Principal investigator: dr Przemysław Adam Płociński

Uniwersytet Łódzki

The use of evolutionary patterns in the optimization of chemotherapy of tuberculosis

Call: SONATA BIS 9 , Panel: NZ6

Principal investigator: dr Alina Ewa Minias

Instytut Biologii Medycznej PAN

Deciphering the role of putative protein factors involved in the mycobacterial DNA strand break repairs

Call: OPUS 17 , Panel: NZ1

Principal investigator: dr Przemysław Adam Płociński

Instytut Biologii Medycznej PAN

Fighting antibiotic-resistant superbugs with anti-persister compounds targeting the strigent response

Call: UNISONO , Panel: NZ6

Principal investigator: dr hab. Ewa Laskowska

Uniwersytet Gdański

Genomic insights into the mechanisms of drug resistance, virulence and transmission of Mycobacterium tuberculosis strain...

Call: DAINA 1 , Panel: NZ6

Principal investigator: dr Tomasz Jagielski

Uniwersytet Warszawski, Wydział Biologii

The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Bożena Renata Dziadek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Immune and metabolomic signatures in chidhood Mycobacterium tuberculosis infections

Call: OPUS 11 , Panel: NZ7

Principal investigator: dr Magdalena Ewa Druszczyńska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Theranostics with nanoporous metal-organic frameworks for inhalable therapy of tuberculosis

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Gabriela Małgorzata Wyszogrodzka

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Molecular and functional analysis of interleukin 18 (IL-18) its receptor (IL-18R) and IL-18- binding protein (IL-18BP) i...

Call: PRELUDIUM 10 , Panel: NZ6

Principal investigator: Sebastian Wawrocki

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

The role of core RNA decay machinery in regulation of metabolism of Mycobacterium tuberculosis

Call: SONATA 10 , Panel: NZ1

Principal investigator: dr Przemysław Adam Płociński

Instytut Biologii Medycznej PAN

RecA independent response of tubercle bacilli to DNA damage

Call: OPUS 10 , Panel: NZ6

Principal investigator: dr hab. Anna Brzostek

Instytut Biologii Medycznej PAN

Vitamin B12 and mycobacterial persistence.

Call: SONATA 10 , Panel: NZ6

Principal investigator: dr Alina Ewa Minias

Instytut Biologii Medycznej PAN