Projects funded by the NCN

Role of protein kinase G type I alpha in the regulation of filtration barrier in glomerular dysfunction.

Call: SONATA BIS 4 , Panel: NZ4

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Structural studies based on low sequence similarity of G protein-coupled receptors activated by hormones and allosteric ...

Call: SONATA 4 , Panel: NZ1

Principal investigator: dr Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I ...

Call: OPUS 3 , Panel: NZ4

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Damian Jacenik

Uniwersytet Łódzki

Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Proteolytic processing of adhesion G-protein coupled receptors through proteases

Call: WEAVE-UNISONO , Panel: NZ1

Principal investigator: dr Renata Mężyk-Kopeć

Uniwersytet Jagielloński

"I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

Call: OPUS 2 , Panel: NZ1

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

Call: PRELUDIUM 21 , Panel: NZ4

Principal investigator: Aleksandra Ryk

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Rational engineering of E. coli penicillin G acylase for quorum quenching-based bacterial control as an effective strate...

Call: PRELUDIUM 20 , Panel: NZ2

Principal investigator: dr Bartłomiej Wojciech Surpeta

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Self-learning systems in the design of compounds modulating GPCR receptors activation.

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

Expression and function of Regulator of G Protein Signaling (RGS) proteins in physiological and pathophysiological condi...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr hab. Maciej Stawnisław Sałaga

Uniwersytet Medyczny w Łodzi

The role of alternative EF-G's in translation regulation during antibiotic biosynthesis in Myxococcus xanthus

Call: OPUS 19 , Panel: NZ2

Principal investigator: dr hab. Agata Lucyna Starosta

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

Call: SONATA 14 , Panel: NZ7

Principal investigator: dr Artur Wnorowski

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological ...

Call: SONATA 14 , Panel: ST5

Principal investigator: dr Justyna Piekielna-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

Call: SONATINA 2 , Panel: NZ7

Principal investigator: dr Sabina Marta Podlewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

Call: OPUS 14 , Panel: NZ7

Principal investigator: dr hab. Agnieszka Anna Kaczor

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

The effect of membrane domains on the G protein-lipid interactions

Call: OPUS 12 , Panel: NZ1

Principal investigator: dr Agnieszka Polit

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Agents affecting the rate of food tolerance development in children with cow's milk protein allergy

Call: PRELUDIUM 11 , Panel: NZ7

Principal investigator: Małgorzata Kaczorowska

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Nauk o Zdrowiu

Molecular mechanism of interactions between GPCRs and G protein.

Call: PRELUDIUM 10 , Panel: NZ2

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk