Projects funded by the NCN
Rational engineering of E. coli penicillin G acylase for quorum quenching-based bacterial control as an effective strategy against antibiotic resistance and biofouling
2021/41/N/NZ2/01365
Keywords:
quorum quenching serine N-terminal hydrolase biofouling antibiotic resistance penicillin G acylase N-acyl-homoserine lactone acylase protein engineering
Descriptors:
- NZ2_008:
- NZ2_010:
- NZ1_009:
Panel:
NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution :
Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii
woj. wielkopolskie
Principal investigator (from the host institution):
dr Bartłomiej Wojciech Surpeta
Number of co-investigators in the project: 2
Call: PRELUDIUM 20 - announced on 2021-03-15
Amount awarded: 43 432 PLN
Project start date (Y-m-d): 2022-01-17
Project end date (Y-m-d): 2024-01-16
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Common Dynamic Determinants Govern Quorum Quenching Activity in N-Terminal Serine HydrolasesAuthors:Bartlomiej Surpeta, Michal Grulich, Andrea Palyzová, Helena Marešová, Jan BrezovskyAcademic press:ACS Catalysis (rok: 2022, tom: 12, strony: 6359–6374), Wydawca: Americal Chemical SocietyStatus:PublishedDOI:10.1021/acscatal.2c00569 - link to the publication