Projects funded by the NCN

Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Emilia Aleksandra Sługocka

Uniwersytet Jagielloński, Collegium Medicum

INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Daria Paulina Zdżalik-Bielecka

Uniwersytet Warszawski, Wydział Biologii

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Designing Active Inhibitors of SARS-CoV-2 Methyltransferases

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Alex Jun Matsuda

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Decrypting the "sulfation code" of glycosaminoglycans for understanding their function in the extracellular matrix

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Chemosensors with molecularly imprinted polymers for determination of antiviral active drug substances in body fluids - ...

Call: OPUS 25 , Panel: NZ7

Principal investigator: dr Krzysztof Robert Noworyta

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Potential of TH cell profiling in personalized multiple sclerosis treatmentplanning.

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Donskow-Łysoniewska

Uczelnia Łazarskiego

Effect of the chronic treatment with lamotrigine on changes in expression of genes related to seizure processes in the s...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Kinga Katarzyna Borowicz

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

Call: PRELUDIUM BIS 4 , Panel: NZ7

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Three-phase drug carriers - design towards a prolonged release, development of a transport model and its verification. C...

Call: PRELUDIUM BIS 4 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

Hybrid materials responsive to external stimuli for local drug delivery in endometriosis treatment - analysis of selecte...

Call: SONATA 18 , Panel: ST5

Principal investigator: dr Olga Urbanek-Świderska

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Digital tools in L2 and L3 vocabulary acquisition. A cross-linguistic investigation

Call: OPUS 24 (LAP) , Panel: HS2

Principal investigator: dr hab. Agnieszka Maria Otwinowska-Kasztelanic

Uniwersytet Warszawski, Wydział Neofilologii

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Regulatory network and interactome of inner membrane drug/metabolite transporters in bacteria – implications for physiol...

Call: OPUS 23 , Panel: NZ2

Principal investigator: dr hab. Aneta Agnieszka Bartosik

Instytut Biochemii i Biofizyki PAN

Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Magdalena Alicja Strachowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

In search of the neural signature of a native and a second language. Using fMRI to investigate a relationship between a ...

Call: PRELUDIUM 21 , Panel: HS6

Principal investigator: Agata Jadwiga Wolna

Uniwersytet Jagielloński, Wydział Filozoficzny

Role of natural products in overcoming drug resistance in Mycobacterium tuberculosis

Call: OPUS 23 , Panel: NZ7

Principal investigator: dr Elwira Zofia Sieniawska

Uniwersytet Medyczny w Lublinie

Dysfunction of NFE2L1 and other family members causes damage in dopaminergic neuron function through dysregulated transc...

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Kamila Łuczyńska

Instytut Genetyki i Hodowli Zwierząt PAN

In Dialogue with the Extreme. The Reception of Paul Celan in the Italian Poetry from the mid-20th Century

Call: OPUS 23 , Panel: HS2

Principal investigator: dr hab. Alessandro Baldacci

Uniwersytet Warszawski, Wydział Neofilologii

Patchwork Parliaments. Post-imperial Field of Power in the Second Republic of Poland, Greater Romania and the Kingdom of...

Call: OPUS 23 , Panel: HS6

Principal investigator: dr Wiktor Henryk Marzec

Uniwersytet Warszawski, Instytut Studiów Społecznych im. prof. Roberta B. Zajonca

Reserved antibiotics and critical priority pathogens in hospital wastewater as an indicator of sanitary-epidemiological ...

Call: OPUS 23 , Panel: NZ7

Principal investigator: prof. Ewa Korzeniewska

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Geoinżynierii

Enzyme Responsive Nanoscale Supramolecular Capsules with Application in Anticancer Drug Delivery

Call: POLONEZ BIS 2 , Panel: ST4

Principal investigator: dr Venkateswarulu Mangili

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Maciej Spiegel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

MOF-antidote": Novel detoxification materials based on metal organic-frameworks for drugs of abuse removal - synthesis, ...

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr hab. Przemysław Jakub Jodłowski

Politechnika Krakowska im. Tadeusza Kościuszki

Biological roles of transcriptional networks activated in the brain by psychotropic drugs

Call: PRELUDIUM BIS 3 , Panel: NZ7

Principal investigator: dr hab. Michał Korostyński

Instytut Farmakologii PAN

The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in t...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Anna Janina Krasowska

Uniwersytet Wrocławski, Wydział Biotechnologii

New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Anna Katarzyna Florczak-Substyk

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Cinemagoing in German-occupied Poland: Cinema programming and film preferences of multi-ethnic urban audiences during Wo...

Call: OPUS 22 , Panel: HS2

Principal investigator: dr hab. Andrzej Dębski

Uniwersytet Wrocławski, Centrum Studiów Niemieckich i Europejskich im. Willy Brandta

The role of the immune checkpoints in the pathomechanism of depressive disorders.

Call: OPUS 22 , Panel: NZ6

Principal investigator: prof. Marta Wanda Kubera

Instytut Farmakologii PAN

Non-canonical pre-mRNA splicing participates in the editing of CNBP mutant allele in myotonic dystrophy type 2 (DM2)

Call: PRELUDIUM BIS 3 , Panel: NZ1

Principal investigator: dr hab. Marzena Wojciechowska

Instytut Chemii Bioorganicznej PAN

New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

Improvement of therapeutic safety of parenteral nutrition in cancer patients - the interplay between supportive drugs an...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Szymon Tomczak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Nationwide Survey of 19-year old adult Polish men: Intergenerational changes of biological traits in relation to socio-e...

Call: OPUS 21 , Panel: HS3

Principal investigator: prof. Sławomir Marek Kozieł

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

IFIT proteins in the regulation of inflammatory responses

Call: OPUS 21 , Panel: NZ2

Principal investigator: dr Maria Wiktoria Górna

Uniwersytet Warszawski, Wydział Chemii

Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Joanna Elżbieta Kałafut

Uniwersytet Medyczny w Lublinie

New 3-methoxypropanamide derivatives in search of effective substances for the treatment of neurological diseases - epil...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Marcin Konrad Jakubiec

Uniwersytet Jagielloński, Collegium Medicum

Phonation in L1 and L2 speech

Call: OPUS 21 , Panel: HS2

Principal investigator: dr hab. Geoffrey Schwartz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Anglistyki

Development of new implantable drug forms, biodegradable nanofibers containing selected betulin derivatives in order to ...

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Janusz Edward Kasperczyk

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

Novel BODIPY derivatives and ruthenium complexes conjugates as photosensitizers for bacterial inactivation in the in viv...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Weronika Porolnik

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Anna Karolina Pogorzelska

Narodowy Instytut Leków

Development of methods of isotope-labeled standards preparation for their quantitative analysis by LC-MS in selected dru...

Call: PRELUDIUM 20 , Panel: ST4

Principal investigator: Paulina Zamiara

Uniwersytet Wrocławski, Wydział Chemii

Benchmarking Human Tissue Culture Systems that Mimic the Tumor Microenvironment

Call: OPUS 21 , Panel: NZ7

Principal investigator: prof. Matthias Nees

Uniwersytet Medyczny w Lublinie

Self-learning systems in the design of compounds modulating GPCR receptors activation.

Call: OPUS 20 , Panel: NZ2

Principal investigator: dr hab. Dorota Latek

Uniwersytet Warszawski, Wydział Chemii

AXL receptor signaling in cancer cell growth and drug resistance

Call: OPUS 20 , Panel: NZ3

Principal investigator: prof. Marta Elżbieta Miączyńska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Parallel quantitative evaluation of targetability, cellular uptake, and intracellular drug release for the establishment...

Call: OPUS 20 (LAP) , Panel: ST5

Principal investigator: prof. Adolfo Rivero Müller

Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

The role of vitamin D receptor in 5-fluorouracil responsiveness of colorectal cancer cells

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Magdalena - Milczarek

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Anna Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Delivery of immuno-activators to phagocytic cells in order to obtain an anti-tumor response

Call: OPUS 20 , Panel: NZ7

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Entangled in common rights. The impact of conflicts over common rights and common lands on socio-economic changes in Wes...

Call: SONATA 16 , Panel: HS3

Principal investigator: dr Joachim Popek

Uniwersytet Rzeszowski, Wydział Humanistyczny