Projects funded by the NCN
Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer
2022/45/N/NZ5/01371
Keywords:
ABC transporters multi-drug resistance PARP1/HPF1 complex gene regulation ADP-ribosylation
Descriptors:
- NZ5_007:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 21 - announced on 2022-03-28
Amount awarded: 139 920 PLN
Project start date (Y-m-d): 2023-02-15
Project end date (Y-m-d): 2025-02-14
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- SMARCA1 regulates PARP1-dependent ABC transporters expression and mediates doxorubicin resistance in triple-negative breast cancerAuthors:Karolina Gronkowska, Kinga Kołacz-Milewska, Sebastian Skoczylas, Éva Nagy, Damian Jacenik, Lóránt Székvölgyi, Agnieszka Robaszkiewicz, Magdalena StrachowskaAcademic press:Biomedicine & Pharmacotherapy (rok: 2025, tom: 192, strony: 46037), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.biopha.2025.118698 - link to the publication