Search results

1. Molecular insights into NAD+ metabolism in Huntington's disease: role in pathophysiology and preclinical assessment of t…

Principal investigator: dr hab. Marta Urszula Tomczyk

Gdański Uniwersytet Medyczny

Call: OPUS 28, Panel: NZ5

2. Identification of novel disease modifiers in Huntington's disease: neuro-glia interactions in the patient-derived multid…

Principal investigator: dr Agnieszka Marta Krzyżosiak

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: SONATA BIS 11, Panel: NZ3

3. Molecular mechanisms of genistein-mediated autophagy stimulation, and its cellular and physiological effects in Huntingt…

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański, Wydział Biologii

Call: OPUS 19, Panel: NZ2

4. Linking abnormal Ca2+ signaling and the unfolded protein response with Huntington's disease pathology in both YAC128 mou…

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 17, Panel: NZ3

5. Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc…

Principal investigator: dr hab. Maciej Figiel

Instytut Chemii Bioorganicznej PAN

Call: OPUS 16, Panel: NZ3

6. Role of arginase 2 in the function of the striatum and in the pathogenesis of Huntington's disease

Principal investigator: dr Michał Tadeusz Węgrzynowicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA BIS 8, Panel: NZ1

7. Modulation of mutant huntingtin level by genistein in the mouse model of Huntington's disease and its effects on psychom…

Principal investigator: Karolina Pierzynowska

Uniwersytet Gdański, Wydział Biologii

Call: PRELUDIUM 13, Panel: NZ2

8. Changes in human skin cells mitochondria carrying mutations causing Huntington's diseasae

Principal investigator: Paulina Jędrak

Uniwersytet Gdański, Wydział Biologii

Call: PRELUDIUM 9, Panel: NZ2

9. MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

Principal investigator: dr Emilia Barbara Kozłowska

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 9, Panel: NZ2

10. Role of CacyBP/SIP in the dysregulation of beta-catenin ubiquitination in YAC128 mouse model of Huntington's disease

Principal investigator: dr Magdalena Czeredys

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: SONATA 8, Panel: NZ3

11. The role of mitochondrial DNA and epigenetic factors in the pathogenesis of Huntington's disease

Principal investigator: prof. Janusz Limon

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: OPUS 2, Panel: NZ2

12. VDAC channel as a target of huntingtin in the etiology of Huntington's disease

Principal investigator: prof. Hanna Małgorzata Kmita

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: OPUS 1, Panel: NZ3

13. The use of artificial miRNAs in the therapy of Huntington's Disease

Principal investigator: dr Anna Kotowska-Zimmer

Instytut Chemii Bioorganicznej PAN

Call: PRELUDIUM 20, Panel: NZ1

14. Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo…

Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

Uniwersytet Warszawski

Call: JPND Call 2022, Panel: NZ2

15. Comprehensive analysis of the therapeutic potential of oligonucleotides for the treatment of polyglutamine diseases

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Call: SONATA 9, Panel: NZ5

16. Searching for new therapeutic targets in polyglutamine diseases

Principal investigator: prof. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ2

17. Human iPSC-derived cortico-striatal assembloids as a new model to studyneurodevelopmental pathologies induced by mutant …

Principal investigator: dr Magdalena Czeredys

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 25, Panel: NZ3

18. Investigation of DNA double-strand break repair mechanisms in microsatellite regions using the CRISPR/Cas system

Principal investigator: dr hab. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 15, Panel: NZ1

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