Projects funded by the NCN

MIST: Artificial intelligence-assisted design of experiments as a tool to streamline the development of siRNA-lipid nano...

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr hab. Paulina Krystyna Skupin-Mrugalska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

RNACTiON: microRNAs and siRNA- mediators in communication between common wheat and pathogenic and symbiotic fungi

Call: OPUS 24 , Panel: NZ9

Principal investigator: dr hab. Lidia Błaszczyk

Instytut Genetyki Roślin PAN

A framework for de novo modeling of RNA structures using restraints derived from experimental data

Call: SONATA 17 , Panel: NZ1

Principal investigator: dr Sunandan Mukherjee

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Functional analysis of bHLH137 in beet - defining the role in response to salinity and salt stress tolerance.

Call: SONATA 17 , Panel: NZ9

Principal investigator: dr Monika Skorupa

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

Identification and analysis of mechanisms controlling steady-state levels and quality of mitochondrial mRNA

Call: SONATA BIS 11 , Panel: NZ2

Principal investigator: dr hab. Roman Józef Szczęsny

Instytut Biochemii i Biofizyki PAN

RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Novel aspects of virulence mechanisms of HopBF1, a bacterial effector that targets host HSP90 protein

Call: OPUS 19 , Panel: NZ1

Principal investigator: dr hab. Magdalena Krzymowska

Instytut Biochemii i Biofizyki PAN

Tyrosine-modified polyethylenimine polymers as a promising vectors for siRNA delivery in synergistic cancer immunotherap...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Małgorzata Kubczak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Key genes/proteins in pollen tube growth - the analysis of calnexin post-transcriptional gene silencing effects in in vi...

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Anna Suwińska

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

Genome-wide siRNA screening for proteins involved in the maintenance of human mitochondrial genome

Call: SONATA 14 , Panel: NZ2

Principal investigator: dr Łukasz Stanisław Borowski

Uniwersytet Warszawski, Wydział Biologii

Analysis of the human SKI complex, a central player in cytoplasmic RNA decay and surveillance pathways

Call: SONATA BIS 7 , Panel: NZ1

Principal investigator: dr hab. Rafał Bogusław Tomecki

Instytut Biochemii i Biofizyki PAN

Reprogramming antitumor innate immunity in gliomas with osteopontin/Spp1 interfering peptides and nanovehicles-delivered...

Call: OPUS 13 , Panel: NZ3

Principal investigator: dr Aleksandra Ellert-Miklaszewska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Preparation and physico-chemical characterization of transfection carriers based on polycationic surfactants.

Call: PRELUDIUM 12 , Panel: ST4

Principal investigator: Weronika Justyna Andrzejewska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

Modified siRNAs, ribozymes and CRISPR/Cas system as strategies for influenza A virus inhibition. Application and compari...

Call: PRELUDIUM 11 , Panel: NZ1

Principal investigator: dr Julita Piasecka

Instytut Chemii Bioorganicznej PAN

Tecto-RNA nano-structures for gene expression regulation in a model system

Call: OPUS 10 , Panel: ST5

Principal investigator: dr hab. Arkadiusz Chworoś

Centrum Badań Molekularnych i Makromolekularnych PAN

The participation of low-molecular regulatory RNAs and their target genes in the development of generative organs in yel...

Call: SONATA 10 , Panel: NZ9

Principal investigator: dr Paulina Glazińska

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych

In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

Call: OPUS 10 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej PAN

Design and synthesis of pH- and redox-responsive dimeric dendrons as a nanotools for transporting siRNA or drugs into gl...

Call: OPUS 10 , Panel: ST5

Principal investigator: prof. Zofia Lipkowska

Instytut Chemii Organicznej Polska Akademia Nauk

Modeling 3D structures and dynamics of RNA complexes with metal ions, with particular emphasis on the formation of non-c...

Call: SONATA 9 , Panel: NZ1

Principal investigator: dr Dorota Anna Niedziałek

Instytut Biochemii i Biofizyki PAN

Mechanisms underlying the targeting of coding sequence repeats by microRNA-like inhibitors

Call: OPUS 8 , Panel: NZ1

Principal investigator: dr Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Genom-wide siRNA screenings for identification of new factors and pathways of human mitochondrial RNA degradation

Call: SONATA 7 , Panel: NZ2

Principal investigator: dr Roman Józef Szczęsny

Instytut Biochemii i Biofizyki PAN

Essential features of miRNA precursors required for release of homogenous siRNAs from shRNA-miR vectors.

Call: PRELUDIUM 6 , Panel: NZ1

Principal investigator: dr Paulina Małgorzata Gałka-Marciniak

Instytut Chemii Bioorganicznej PAN

Thermodynamic insights into design of functionally optimized modified siRNAs and their experimental verification.

Call: SONATA BIS 3 , Panel: NZ1

Principal investigator: dr hab. Anna Pasternak

Instytut Chemii Bioorganicznej PAN

The selective gene silencing, as the advanced research tool in evaluation of AngII influence on tumorigenesis in endomet...

Call: OPUS 5 , Panel: NZ4

Principal investigator: dr hab. Agnieszka Wanda Piastowska-Ciesielska

Uniwersytet Medyczny w Łodzi, Wydział Nauk Biomedycznych i Kształcenia Podyplomowego

The study of the role of mGluR8 in cancer cells - a potential target for new antitumor strategies

Call: OPUS 3 , Panel: NZ3

Principal investigator: dr Danuta Jantas

Instytut Farmakologii PAN

Conjugated linoleic acid (CLA)-induced transcriptional activation of PPAR-an investigation of molecular machanisms of pu...

Call: OPUS 2 , Panel: NZ9

Principal investigator: prof. Teresa Leszczyńska

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Technologii Żywności

Legends of St Catherine of Siena in late medieval French literature - critical edition of texts and a philological study

Call: OPUS 2 , Panel: HS2

Principal investigator: dr hab. Piotr Tylus

POLSKA AKADEMIA UMIEJĘTNOŚCI

Investigation of the RNA secondary structure in vivo with employment of high-throughput sequencing techniques

Call: SONATA 2 , Panel: NZ2

Principal investigator: dr Marek Żywicki

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii UAM

The synthesis and physicochemical analiysis of new delivery systems for gene therapy and siRNA transfection

Call: OPUS 1 , Panel: ST5

Principal investigator: dr hab. Maciej Leszek Kozak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki